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Tag: "clone" at biology news

Scientists clone mice from adult skin stem cells

...at adult stem cells taken from skin can be used to clone mice using a procedure called nuclear transfer. Th...e scientists have tried to use adult stem cells to clone mice. Experiments using adult hematopoetic stem cells ?the cells in the bone marrow that all blood c...

Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine

...and time-consuming process required to isolate and clone the antigens for vaccine development. In workin...Wistar Institute have now developed a novel way to clone an antigen recognized by a helper T cell. Already, Herlyn's group has used the new cloning technique...

Cancer researchers add spice to research against rare neuromuscular disease

...ewer treatments. In 1988 Chang was the first to clone the androgen receptor, and he was the first to discover that the protein needs molecular allies called co-factors to accomplish many of its tasks. Now more than 70 co-factors are known, offering many new targets to potentially stop conditions like Ke...

Cloned mice created from fully differentiated cells, a milestone in cloning research

... could develop to the blastocyst stage and not one clone was produced. With such odds, it's hard to believe that Dolly and other cloned animals could have possibly been derived from adult stem cells. Much more likely is that these animals were derived from fully differentiated tissue cells," Dr. Yang argue...

The power of one: A simpler, cheaper method for cell fusion

...ease-specific antibodies and has helped scientists clone mammals. The current technique for electrofusion requires a pricey electrical pulse-generator, which could cost as much as $13,000. Lu's technology, on the other hand, uses a $100 DC power supply, which, unlike the specialized generator, can be us...

Scientists crack genetic secrets of human egg

...e a known function yet," Cibelli said. "Now we can clone these genes and put them into cells and see if they may have a role in the creation of stem cells - without fertilization or destruction of human embryos." Cibelli believes some of those genes know the big secrets - such as when a cell should slow ...

Genetic study of Neanderthal DNA reveals early split between humans and Neanderthals

... well as the new parallel pyrosequencing method to clone and insert missing fragmented DNA and create a library of Neanderthal DNA. Unlike the libraries used to sequence the human genome, which contained only human DNA fragments, the Neanderthal DNA library is riddled with contamination from microbes tha...

Cloning techniques produce FDA-approved antibiotic

...t William W. Metcalf, the researchers were able to clone the essential genes for fosfomycin synthesis and then produce it in a non-native host, potentially in much larger quantities. After isolating the genetic information from fosfomycin's native host, Streptomyces fradiae, certain genes were inactivate...

P(acman) takes a bite out of deciphering Drosophila DNA

...o the strategy, which facilitates the scientist to clone large chunks of DNA and subsequently allows them to make specific mutations anywhere he or she wants in the gene. The third technique allows the researcher to pinpoint where he or she wants to the mutant gene to go in the genetic blueprint of the...

Eminent inventor of DNA fingerprinting gains new recognition

...even able to tell us whether Dolly was in fact the clone of another sheep. "The new discipline of forensic molecular biology is therefore a direct outcome of Jeffreys' research, but his discoveries have also opened up other doors, for example the ability to determine whether someone is a carrier of certai...

Leptin found to control appetite and limb development in frogs

...er's lab had some puzzles to solve to successfully clone the frog gene. But once they solved those issues and put the gene into E. coli bacteria to make quantities of leptin, the frog protein turned out to be functionally very similar to the human version, Denver notes. "It would appear that leptin and i...

Ten years later, Dolly is still making headlines

... team of scientists who were first to successfully clone an animal, Dolly the sheep, ten years ago, will speak about his plans to clone embryos to alter disease genes in humans. Wilmut will be joined by two other leaders in biotechnolog...

UAB researchers confirm HIV-1 originated in wild chimpanzees

...es. The UAB investigators went on to molecularly clone and sequence the complete viral genomes from four individual chimpanzees. According to UAB post-doctoral researcher Brandon Keele, Ph.D., lead author of the report, "this allowed for unprecedented genetic comparisons to be done between HIV-1 and its ...

MIT researchers build tiny batteries with viruses

...irus to grow the electrode material, we can easily clone millions of identical copies of the virus to use in assembling our batteries. "For the metal oxide we chose cobalt oxide because it has very good specific capacity, which will produce batteries with high energy density," meaning it can store two or ...

Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections

...kin and soft tissue infections are due to a single clone or strain of MRSA called USA300. As noted in the accompanying editorial, MRSA appears to have emerged as a cause of community-acquired skin infections in other U.S. communities as well. As noted by Dr. Blumberg and other Emory and Grady authors, ...

Removing DNA repair gene causes metabolic syndrome

...nterest in NEIL1 was initiated by their efforts to clone and crystallize homologs to the Escherichia coli endonuclease VIII gene. E. coli endonuclease VIII is part of a pathway of enzymes involved in repairing DNA damaged by free radicals that trigger oxidative stress on cell molecules. As a consequence of...

Cloned stem cells prove identical to fertilized stem cells

...hy scientists generally believe that attempting to clone a human being is morally reprehensible. But are the cloned embryo's stem cells beleaguered by the same defects? Studies have demonstrated that a small number of stem cells in the blastocyst appear to be spared this faulty reprogramming. When stem ...

New study to explore cellular circuitry

...r exact copies of the genes of the yeast cell, one clone for each known protein present in the cell. What makes the set of clones useful is that each one manufactures large amounts of a single protein with a "tag" attached. One common application of the library is to separate the tagged proteins from all...

UIC developing drug for SARS

...hijacking the machinery of the cells it infects to clone itself over and over again. One of the first steps in that process is the production of a long chain of proteins, all of which are needed for the virus to propagate. Two enzymes, or proteases, clip the chain to release the individual proteins, the p...

Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005

Scientists in Belgium have discovered how to clone human embryos from eggs that have been matured in the laboratory. Their discovery should make it easier for scientists to create embryonic stem cell lines from cloned embryos and develop them to provide eggs and sperm for infertile couples, the 21st ...

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