Effective Cancer Treatments Follow The Clock
...most active point in its cycle.?/p> Biological clocks function in the brain as well as lung, liver, heart and skeletal muscles. They operate on a 24-hour, circadian (Latin for "about a day") cycle that governs functions like sleeping and waking, rest and activity, fluid balance, body temperature, cardia...Glow-in-the-dark zebrafish at UH hold keys to biological clocks
... something in their genetic makeup that gets their clocks ticking without parental influence, however, we de...chance of identifying mutant fish whose biological clocks run fast or slow, providing the ability to trace the specific genes that create the anomaly. Putting...Researchers Identify Cause of Early Bird Sleep Disorder
...ircadian clock, and suggest that mammalian and fly clocks may have different regulatory mechanisms, despite the highly conserved nature of their individual components," the research team wrote in Nature. Such studies may help unravel some of the fundamental mysteries of how circadian rhythms are established...How monarch butterflies are wired for navigation
...adian clock in the butterfly brain. Such circadian clocks govern the approximately 24 hour activity and metabolic cycles of animals from the simplest insects to humans. Reppert and his colleagues found that key genes responsible for the clock's molecular "ticks" were expressed in a brain region called the d...Gene controlling circadian rhythms linked to drug addiction
The gene that regulates the body's main biological clocks also may play a pivotal role in drug addiction, researchers at UT Southwestern Medical Center have found. The Clock gene not only controls the body's circadian rhythms, including sleep and wakefulness, body temperature, hormone levels, blood pressur...What Makes The Brain Tick, Tick, Tick: Researchers Gaining New Insights Into Brain's Internal Clock
...erstanding all its functions. The brain's internal clocks coordinate a vast array of activities from communi...one of the brain's most important, and mysterious, clocks -- the one governing timing intervals in the seconds to minutes range. Such interval timing occupies...A resetting signal keeps circadian rhythm on track in Drosophila fruit flies
... clock. The results showed clearly that these two clocks always remained coupled in a network that was gove...re state-of-the art. Fortunately, their circadian clocks and even neural mechanisms are quite conserved with mammals." "We were curious about how these brai...Clock molecule's sensitivity to lithium sheds light on bipolar disorder
...cells in the incubator need to have their internal clocks reset, maybe this is what happens in some people w...says Lazar. "One effect of lithium may be to reset clocks that become stuck when Rev-erb levels build up." These results point to Rev-erb as a lithium-sensi...More evidence mammals, fruit flies share make-up on function of biological clocks
...nly used for research on biological, or circadian, clocks because of the relative ease of finding mutants with non-24-hour rhythms and then identifying the genes underlying the altered behavior. These studies in fruit flies have allowed the identification of similar "clock genes" in mammals, which function ...Protein shown to rally biological clock
...n the other. Together these neurons are intrinsic clocks in communication with each other to keep 24-hour time. It had been thought that GABA was the prime candidate for the rallying role. All SCN neurons make this inhibitory neurotransmitter, and it had been shown that giving GABA daily at 8 a.m. to ...Chronic jet-lag conditions hasten death in aged mice
...omplex. Past research has indicated that circadian clocks govern physiological rhythms in a great variety of tissues in the body, and that different aspects of the physiological clock can adjust to schedule changes at different rates. The researchers speculate that the internal lack of synchrony among diffe...How does your brain tell time?
... we didn’t have access to the plethora of watches, clocks and cell phones at our disposal? For ...ut the brain, and do not resemble the conventional clocks we wear on our wrists," said Buonomano. Because time-related information is critical to understan...Gene that makes people 'early to bed and early to rise' demystified
...ps to explain just how their bodies' natural alarm clocks get set to such an early wake-up time. In studies...middle of the night, to synchronize their internal clocks with their regular or changing daily routines, the researchers said. Someday "people with jet lag ...Keeping the body in sync -- The stability of cellular clocks
...ses the tools of physics to show how our circadian clocks manage to keep accurate time in the noisy cellular...ipheral organs in the body have their own cellular clocks that are reset on a daily basis by a central master clock in the brain. The operation of the cellula...Caribbean frogs started with a single, ancient voyage on a raft from South America
... species with molecular-clock methods. "Molecular clocks work by counting the number of DNA-sequence mutations separating two species and then dividing that number by the rate of change, which is established with the help of fossils and geologic information," explained Hedges. The study's DNA research r...