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Tag: "clock" at biology news

Sleepless for science: Flies show link between sleep, immune system in Stanford study

...he sick ones. "We want to know how the internal clock knows the animal is infected, and how does the imm... immunity. "The cool thing is that many of the clock genes are conserved between flies and vertebrates; we have 'period' and we have 'timeless'," said Sc...

Individual differences in a clock gene predict decline of performance during sleep deprivation

...now found that a genetic difference in a so-called clock gene, PERIOD3, makes some people particularly sens...ght. The findings highlight a possible role for clock genes in human sleep physiology and structure, and the influence these genes might have on performan...

Keeping the body in sync -- The stability of cellular clocks

...hat are reset on a daily basis by a central master clock in the brain. The operation of the cellular clocks...the coordinated action of a limited number of core clock genes. The oscillators work like this: the cell receives a signal from the master pacemaker in the h...

Gene that makes people 'early to bed and early to rise' demystified

...und that the mutant version of the Period 2 (Per2) clock gene--which is crucial for resetting the body's central clock in response to light--cannot be chemically modified by another enzyme that controls it. That failure...

DNA ends: Common tool, different job

...his progressive shortening to a genetic biological clock that winds down over time. In fact, when telomeres reach a "critical length," the cell can no longer multiply ?a characteristic sign of cellular senescence. In certain cells, such as our germ cells or baker's yeast cells, which need to divide ind...

How does your brain tell time?

...have believed that the brain possesses an internal clock that allows it to keep track of time. Now a UCLA study in the Feb. 1 edition of Neuron proposes a new model in which a series of physical changes to the brain’s cells helps the organ to monitor the passage of time. "The value of this research lie...

Chronic jet-lag conditions hasten death in aged mice

...y, and that different aspects of the physiological clock can adjust to schedule changes at different rates. The researchers speculate that the internal lack of synchrony among different physiological oscillations may have serious health consequences that are exacerbated in aged animals. ...

Negative effects of caffeine are stronger on daytime sleep than on nocturnal sleep

...shallow to override the signal from the biological clock that tells the body it should be awake at this time of day," explains Dr. Carrier. "We often use coffee and other sources of caffeine during the nighttime to counteract sleepiness generated by sleep deprivation, jet lag, and shift-work. However, this...

Pourquié lab identifies genes involved in formation of vertebral precursors

...spine and the role of an internal mechanism -- the clock oscillator -- that regulates the formation somites...e team used the mouse model to demonstrate how the clock drives the periodic expression of a large network of cyclic genes involved in cell signaling. Mutual...

Circadian gene helps the brain predict mealtime

...n the brain's ability to run its central circadian clock according to daylight. The researchers found that, interestingly, synchronization of timing between organs by scheduled meals is not affected by the Period 2 mutation, indicating that this gene is not crucial for scheduled food availability to af...

Protein shown to rally biological clock

...llying protein that signals the brain’s biological clock to coordinate daily rhythms in behavior and physiology. The finding clarifies the roles that both VIP and a neurotransmitter GABA play in synchronizing biological clocks, and sheds light on how mammals, in this case mice and rats. regulate circadi...

Diabetes research takes wing thanks to long-lived fruit fly

...? Perhaps it's possible to re-set the body's aging clock and maybe make someone live longer." It was Bohmann's questions about cancer-causing genes 20 years ago that led him to focus on JNK, a signaling system that plays a role not only in cancer but in many normal body processes. For several years he has...

Tigers get a business plan

...The Tigers Forever initiative begins today and the clock is running. ...

Novel connection found between biological clock and cancer

... implies a protective dimension for the biological clock in addition to its pacemaker functions that play s...thms and activities of life. "The notion that the clock regulates DNA-damage input and that mutation can affect the clock as well as the cell cycle is novel...

New fruit fly protein illuminates circadian response to light

...rstanding the process by which the body's internal clock synchronizes to light. Understanding how light aff...o future treatments of jetlag. The body's 24-hour clock controls a multitude of internal functions such as periods of sleep and wakefulness, body temperatur...

More evidence mammals, fruit flies share make-up on function of biological clocks

...toreceptor, which helps light reset the biological clock with changing seasons, or in jet lag-style experim... Cry assists in the 24-hour rhythmic expression of clock genes and has nothing to do with re-setting the clock. The researchers sought to determine additio...

New Research Shows Artificial Light at Night Stimulates Breast Cancer Growth in Laboratory Mice

...he body’s circadian rhythm, an internal biological clock that regulates sleep ?wake cycle, body temperature...nce is emerging that disruption of one’s circadian clock is associated with cancer in humans, and that interference with internal timekeeping can tip the bal...

Clock molecule's sensitivity to lithium sheds light on bipolar disorder

... is a critical component of the internal molecular clock in mammals. What's more, this molecule –called Rev...suggest a relationship between the human circadian clock and metabolism. Proteins are the gears of the clock, and not much is known about what regulates prot...

Travelers can avoid jet lag by resetting their body clocks

...to avoid jet lag by resetting their circadian body clock before crossing several time zones, according to n...isalignment between a person's internal biological clock and the external social environment. Both bright light and melatonin have successfully been used in...

A resetting signal keeps circadian rhythm on track in Drosophila fruit flies

...a molecular signal maintains coherence among brain clock cells that regulate daily activity of Drosophila m...is conclusion by speeding up only the morning cell clock or only the evening cell clock. The results showed clearly that these two clocks always remained co...

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