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Tag: "clinical" at biology news

Prenatal Stress Keeps Infants, Toddlers up at Night, Study Says

...carry-over to the child, OConnor said. Still, more clinical research is needed to see how we can best promote healthy pregnancies and healthy babies. The ALSPAC study, part of the WHO-initiated European Longitudinal Study of Pregnancy and Childhood, is funded by the Wellcome Trust, the National Institutes ...

Scratch no more: Gene for itch sensation discovered

... itch sensation and possibly move that research to clinical applications fairly soon."...

Enzyme delivered in smaller package protects cells from radiation damage

...dy irradiation, and in preparation for a potential clinical trial of systemic MnSOD in humans, the University ..., whose group is currently conducting a phase I/II clinical trial in lung cancer patients consisting of twice-weekly swallowed MnSOD for protection of the esoph...

Blood test may help signal tumor's remission, return in throat cancer patients

...p turn off NF-kappaB are currently being tested in clinical trials at NIH and elsewhere. The researchers note that a few of the patients experienced elevations in cytokine levels related to other illnesses or injuries, and not to throat cancer; therefore, they caution that further studies are needed in lar...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

...nitored blood counts, renal and liver function and clinical signs and symptoms. They then performed statistica...dent of an individual’s hepatic reserve, tumor and clinical factors,” the authors report. Though the study was limited by a small patient cohort, and the fa...

Old memory traces in brain may trigger chronic pain

...results, the next step will be to test the drug in clinical trials, Apkarian said. “When we do this in a clinical trial, we expect people to say I still have the pain, but it’s not bothering me anymore,” Apkarian s...

Modeling the restless brain

...rsons. Sporns said this research could lead to clinical applications, offering new diagnostic tools for brain disorders such as Alzheimer's disease that are known to affect the brain's connections. It also could help explain why humans do not think alike. "If fluctuations in brain activity are shaped ...

Research team identifies new Alzheimer's gene

...ture of how life works and ultimately allow better clinical management of patients,” said Dr. Dietrich Stephan... will enable Kronos to develop a test that aids in clinical diagnosis and help determine a person’s genetic predisposition for developing Alzheimer’s disease. ...

Studies to find better ways to preserve human eggs, ovarian tissue under way

...ysterectomy for benign disease, says Dr. Song, MCG clinical associate professor at MCG and director of research for Augusta-based Xytex Research/Xytex International. Collaborators at the University of Texas Health Science Center and M.D. Anderson Cancer Center are doing the same. With some of the tis...

Brain holds clues to bipolar disorder

...oved medications many of which are being tested in clinical trials. Mary Phillips, M.D., professor of psychiatry at the University of Pittsburgh School of Medicine and director of functional neuroimaging in emotional disorders at Western Psychiatric Institute and Clinic of UPMC, will discuss the emerging r...

Brightening prospects of using fluorescent nanotubes in medical applications

...archers will begin considering ways to use them in clinical applications.” The figure of merit for fluorescence is quantum efficiency: the ratio of the number of photons of light that a device emits to the number of photons it absorbs in the process. The VINSE team reports that they can produce populations ...

Research shows cord blood comparable to matched bone marrow

...tes. The study was done by extensive review of clinical data from transplant centers around the country and reported to the CIBMTR at the Medical College of Wisconsin, Milwaukee and the National Cord Blood Program at the New York Blood Center. The analysis included transplant outcomes in 785 children youn...

Breakthrough developments in rheumatoid arthritis reported

...rch subjects with rheumatoid arthritis. With these clinical features at his side, he turns to the basic building blocks of life – the human genome – to figure out what makes these people susceptible to the disabling inflammatory condition. Dr. Gregersen has finally closed the circle between key genes identi...

'Lucky 13' as new gene discovery offers further hope for childhood blindness

... Hospital, London, recently announced the start of clinical trials for a gene therapy involving injecting gene...our findings, together with the recently announced clinical trials, hold great promise." Mutations in LCA5 are relatively rare. As it is a recessive gene, a ...

Newly discovered antibody may be body's natural defense against Alzheimer's

...sbyterian/Weill Cornell and associate professor of clinical neurology at Weill Cornell Medical College. Dr...loid levels in Alzheimer's patients in our Phase I clinical trial were much more profound than we expected," Dr. Relkin explains. "We couldn't readily explain t...

Researchers shed light on mechanism of action used by anti-cancer drug

...eral such targeted agents are currently undergoing clinical evaluation in patients with various malignancies....

Study finds mix of disease processes at work in brains of most people with dementia

...ess, however, an individual’s likelihood of having clinical signs of dementia increases with the number of dif...heir brains upon death. The current study compared clinical and autopsy data on the first 141 participants who have died. Annual physical and psychological e...

454 sequencing identifies HIV drug resistance at early stage

... HIV variants in samples from an earlier performed clinical trial. The work, presented today by Michael Kozal...se resistant HIV strains which will lead to better clinical responses in patients.” While treatment of HIV has been largely successful, with dramatic increas...

University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts

...‘off-the-shelf,’ which is an essential element for clinical translation,” he explained. ...

Potent possibilities for parasite attack

...losely related organisms to cause vastly different clinical outcomes is a major quest for researchers and in t...nfection and the host genome plays a major role in clinical outcome." The results picked up another surprising finding: the team could assign a function to o...

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