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Tag: "cirrhosis" at biology news

Risk of lymphoma increases with hepatitis C virus infection

...ct, among other means. HCV is also known to cause cirrhosis and liver cancer. "Although the risk of developing lymphomas is small, our research suggests that screening of HCV-infected individuals could identify conditions which may lead to cancer. It might then be possible to prevent progression to lymph...

Double the death rate from cirrhosis for 'blue collar' men

...amined death rates among Australian men from liver cirrhosis between 1981 and 2002. Their results were publis...cause of their heavy and binge drinking. Liver cirrhosis accounted for 3.3 percent of all deaths among men aged between 15 and 64 in Australia in 2002 (543) ...

Protein found that slows hepatitis C growth in liver cells

...om that treatment fails are at high risk for fatal cirrhosis or liver cancer. In the United States, about half of all liver cancer cases occur in people infected by hepatitis C virus. The UTMB scientists reported their findings in the April 20 issue of the Journal of Biological Chemistry. Their article is e...

New test helps identify hepatitis C patients at high risk of developing cirrhosis

...ntify patients who are at high risk of developing cirrhosis from chronic hepatitis C infection. That means hi...e better off delaying treatment. "Management of cirrhosis patients is challenging," said Ramsey Cheung, MD, associate professor of medicine at the school and...

Light wine intake is associated with longer life expectancy in men

...ay cause accidents and diseases such as cancer and cirrhosis of the liver, even though this was not observed in our study. Since alcohol consumption can be addictive, starting to drink alcohol because of its positive health benefits is not advised." How alcohol or wine might affect cardiovascular risk merit...

Interaction between lymph and liver cells may affect immune response

...ions associated with loss of fenestrations such as cirrhosis and old age," the authors conclude. "We have shown [in previous studies] that old age is associated with dramatic reductions in the fenestrations of LSECs therefore the altered immune responses of older people might in part be mechanistically linked ...

Molecular 'on/off switch' controls immune defenses against viruses

....S. residents and is the nation's leading cause of cirrhosis and liver cancer. In 2005 Dr. Gale and his team completed several breakthrough studies on hepatitis C, discovering that the RIG-I protein binds to viral genetic material. Then, RIG-I changes its shape and sends signals to other proteins that spur...

Statins stop hepatitis C virus from replicating

...ercent face a threat of the disease progressing to cirrhosis and liver cancer. Based on recent reports that one statin, lovastatin, inhibits HCV replication, researchers led by Masanori Ikeda of Okayama University in Japan, tested other statins in search of a more effective anti-HCV therapy. Using the OR6 cel...

Texas scientists discover how a hepatitis C protein promotes liver cancer

...ts. Those who fail treatment are at risk for fatal cirrhosis or developing liver cancer. Researchers have known for a long time that hepatitis C virus infection can lead to liver cancer. But how the virus goes about this has been unclear. The UTMB group discovered that the tumor-suppressing retinoblastoma p...

Investigating 'brain shrinkage' in alcoholics

...?particularly the alcohol, thiamine deficiency and cirrhosis ?are linked and probably contribute in a complex w...unction. Structural and functional changes seen in cirrhosis of the liver are also potentially reversible if treated. Furthermore, thiamine deficiency can be tre...

Identification of specific genes predicts which patients will respond to Hepatitis C treatment

...er time the viral infection leads to liver damage, cirrhosis and/or liver cancer. It is currently the leading indication for liver transplants. Liver biopsies were performed on the 31 chronic HCV patients before treatment, and were compared to 20 biopsies from healthy, uninfected livers. 16 patients did not r...

FDA Approves New Treatment for Chronic Hepatitis B

...the liver. The virus can cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure, and death. According to the Centers for Disease Control and Prevention, approximately 1.25 million Americans are chronically infected with the HBV virus. Baraclude slows the progression of chroni...

UCLA study assesses cost-effectiveness of Hepatitis B drugs

...enarios including viral resistance, development of cirrhosis and other factors affecting treatment. Health cost...nic hepatitis B disease can lead to liver failure, cirrhosis or cancer of the liver. About 90 percent of healthy adults who are infected with Hepatitis B recover...

Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis

...n the process that spans from hepatic steatosis to cirrhosis and hepatocarcinoma. NASH is one of the most common causes of elevated aminotransfereases in patients referred for evaluation to hepatologists. Obesity and type-2 diabetes are associated to NASH. Since the prevalence of these diseases is increasing, ...

Surprising findings reported about iron overload

...et organs that may result in complications such as cirrhosis of the liver, liver cancer, arthritis, diabetes, impotence and heart failure. "The finding that Asians and Pacific Islanders have high levels of iron in the blood is surprising because they also have the lowest prevalence of the particular gene muta...

Research Gives Hope For Liver Damage

...d increase in the number of men aged 45-54dying of cirrhosis since 1970 and a threefold increase in women of th...atients with advanced liverfibrosis (scarring) and cirrhosis (end stage scarring of the liver).Currently, we have no effective treatment for liver cirrhosis whic...

Studies reveal methods viruses use to sidestep immune system

...through sexual contact and is the leading cause of cirrhosis and liver cancer. UT Southwestern Medical Scientist Training Program (MSTP) student Eileen Foy was an author on all three papers. MSTP student Rhea Sumpter and postdoctoral researcher Dr. Yueh-Ming Loo were authors on two of the papers. Postdoctoral...

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