First human trial of antibacterial contact lens
...at biofilms account for at least two-thirds of all chronic bacterial infections. Biosignal and the Institute for Eye Research have tested antibiofilm compounds and generated proof of concept data in a broad range of product categories in the medical, industrial and consumer fields. ......e experience with what is known as medihoney. Even chronic wounds infected with multi-resistant bacteria often healed within a few weeks. In conjunction with colleagues from Düsseldorf, Homburg and Berlin they now want to test the experience gained in a large-scale study, as objective data on the curative pr...Mice lacking key immune component still control chronic viral infections
... a line of genetically engineered mice can control chronic herpes virus infections, researchers at Washington... immune system elements play a role in controlling chronic viral infections." The study will be published in the May issue of Public Library of Science Patho...New genes implicated in rheumatoid arthritis
...or genetic clues into rheumatoid arthritis (RA), a chronic inflammatory joint disease. While its specific cause is not yet known, RA has been linked to an inherited susceptibility. Interestingly, despite its strong genetic component, RA's occurrence among siblings seems to be random. In the quest to ide...DNA: Bacteria's survival ration
..., Finkel said. Biofilms, which have been linked to chronic infections, also may harbor nutritionally competent germs. If researchers succeeded in turning off nutritional competence in such pathogens, as Finkel did in E. coli, the advance might lay the groundwork for a new class of genetic antibiotics. The ...First human study confirms that immune cells can be a primary cause of bone loss in gum disease
...makes periodontal disease very distinct from other chronic infectious diseases. B cells are known to produce a weapon (antibody) that normally attacks bacteria and protects our body from bacterial infection. As a consequence of dense infiltration of B cells found in the gum, periodontally diseased patients m...How can identical twins be genetically different?
... July issue of Arthritis and Rheumatism. RA is a chronic inflammatory disease that damages joints. RA causes pain, loss of movement, and bone deformities. It affects 2.1 million Americans. There are many genetic factors that put people at a high-risk for developing RA, yet only 15 percent of identical twin...Cycles of cell death, proliferation key to liver cancer
...chemicals, including alcohol ¡V all of which cause chronic liver injury and inflammation. Although not common in the United States., the incidence of HCC is on an upward trajectory, with little hope for treatment or cure through chemotherapy, radiation or other traditional cancer treatments. "We now unders...Many cleaners, air fresheners may pose health risks when used indoors
...when the products are used regularly, resulting in chronic exposure, according to the study. The study is the first to measure emissions and concentrations of primary and secondary toxic compounds produced by these products under typical indoor use conditions, and it examines the potential hazards of small-...Mouse mimics chronic leukemia, will aid drug development
...e first real animal model for an incurable form of chronic leukemia and should greatly aid the development of...c mouse, develops a malignancy that closely mimics chronic lymphocytic leukemia (CLL). The lack of an animal model has greatly hampered the development of new ...Scientists aim to thwart use of flu as bioweapon
...ce, HIV infection is now more commonly viewed as a chronic infection thanks largely to improved treatment. Much of the improvement is due to early mathematical models that helped scientists and physicians understand and target the disease more effectively. "How flu infects the body and how the body responds...Nutrition a major factor in rise in twin pregnancies
...en awaiting IVF appear to prefer the prospect of a chronic adverse birth outcome rather than childlessness", said Mr. Scotland. "Having no child at all was valued significantly lower than having a child with physical, cognitive or visual impairments, but significantly higher than perinatal death. Our work...Five surprising facts about starvation that could change the international agenda
...veral examples of development that will reduce the chronic undernutrition that results in wasting of children. These include improving nutrition in pregnant and lactating women to prevent low-birthweight babies, effective protection against infectious disease, improved water and sanitation systems, promotion...How HIV 'exhausts' killer T cells
...lso likely have application in understanding other chronic viral diseases. The findings by Walker and h...by co-author Rafi Ahmed of Emory. Ahmed found that chronic viral infection actively inhibits T cells by switching on the cells' inhibitory PD-1 pathway. He als...A new tool against brain disease
...lso likely have application in understanding other chronic viral diseases. The findings by Walker and h...by co-author Rafi Ahmed of Emory. Ahmed found that chronic viral infection actively inhibits T cells by switching on the cells' inhibitory PD-1 pathway. He als...Novel therapy combinations gain ground in treating hepatitis
...nts with Chronic Hepatitis C [Abstract S1060] In chronic diseases like hepatitis, symptoms have a tendency ...the current standard of 48 weeks, in patients with chronic hepatitis C. Previous studies have shown that with 48 weeks of therapy, relapse rates are near 20 ...Pollution threatens coral health by preventing lesions from healing, UCF study shows
...al development and treated wastewater discharge as chronic problems along Florida's southeast coast. The loss of coral harms natural reef ecosystems and can hurt Florida's tourism economy if divers decide to go elsewhere. Reefs also help to protect coastal areas from hurricanes, as they break up storm sur...Study details hepatitis C ability to block immune system response
...wly infected annually. HCV is the leading cause of chronic liver disease including hepatic fibrosis, end-stage cirrhosis, and hepatocellular carcinoma. There is no vaccine available to prevent HCV, and current therapies are costly, have serious side effects and are curative in only a fraction of patients. Ac...New strategy rapidly identifies cancer targets
...g Gleevec, which Druker pioneered for treatment of chronic myelogenous leukemia. Since its approval in 2001, Gleevec has made CML a much more manageable disease. A new drug to inhibit JAK3 is already in development elsewhere, and, eventually, Druker sees a market filled with a dozen or more tyrosine kinas...Bedsores and bald hides: Novel roles revealed for a 'scaffolding' protein
...d may have implications for preventing or treating chronic wounds such as pressure or bed sores arising from long periods of immobility. Along with the pain and scarring, bed sores significantly increase health care costs in nursing homes and hospitals. A separate report by the same Hopkins group, publishe...