Novel method reveals how menthol discovery could point towards new or improved pain therapies
...f temperature-activated ion channels can result in chronic pain syndromes," said Ardem Patapoutian, associate...these ion channels are considered targets to treat chronic inflammatory and neuropathic pain indications. Understanding how small molecules such as menthol af...Dogs keep dying: Many owners unaware of toxic dog food
...gns." She suspects that surviving dogs may develop chronic liver disease, perhaps liver cancer, and that many dogs that ate the tainted food appear healthy are nevertheless victims of liver damage. Yet many dog and kennel owners remain unaware that some 19 brands of Diamond, Country Value and Professional d...A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases
... could provide a method to treat a wide variety of chronic inflammatory diseases. "It appears that IL-25 ha...25 can be considered a "good" cytokine by limiting chronic inflammatory responses. At the same time, the ability of IL-25 to promote type 2 responses that dri...Efficiency, not more doctors, is the prescription for aging population
...s and fewer resources in managing of patients with chronic illnesses when compared to other academic medical ... The research focuses on the management of severe chronic illness because it is the area where health care resources are most heavily used--about half of Medi...New licensing agreement to maximize AIDS drug development
...Strakan, for the treatment of pain associated with chronic anal fissures. A similar formulation of Rectogesic is currently being sold in Australia, New Zealand, Singapore and South Korea. FortigelTM (testosterone gel), branded Tostrex® outside the United States, is marketed in Sweden for the treatment of m...Pennsylvania researchers find liver transplants provide metabolic cure for rare genetic disease
... and even sudden death. Over a patient's lifetime, chronic instability of blood amino acids can result in ser...splantation protects patients from these acute and chronic neurological complications. It is a reasonable alternative to nutritional therapy, particularly for ...Epstein-Barr virus may be associated with multiple sclerosis
... influence the risk for multiple sclerosis (MS), a chronic autoimmune disease that affects the central nervous system, according to background information in the article. Some studies have suggested that the Epstein-Barr virus, which affects up to 96 percent of Americans by the time they reach age 35 to 40 ...Big hips, big belly? It's in your genes, Joslin-led study shows
... influence the risk for multiple sclerosis (MS), a chronic autoimmune disease that affects the central nervous system, according to background information in the article. Some studies have suggested that the Epstein-Barr virus, which affects up to 96 percent of Americans by the time they reach age 35 to 40 ...All placebos not created alike
...an inert pill." The study of 270 individuals with chronic arm pain had two phases. In the first phase, 135 patients were given sham acupuncture, and another 135 patients were given a placebo pill for two weeks. During this period, investigators found no strong evidence for an enhanced effect with placebo ...New method enables gene disruption in destructive fungal pathogen
...Alternaria are involved in the development of such chronic airway diseases as asthma, allergy and chronic rhinosinusitis. Gene disruption methods could help in identifying molecules from the fungus that tri...A case of mistaken molecular identity
... But the parasite remains active inside them, in a chronic phase of infection, quietly invading cells and stimulating the immune system. As a result, people can develop heart and gastrointestinal problems months or years after being infected. Some 30,000 people die each year from Chagas disease, according to...Inflammation and drugs to control this activity studied in a variety of tumors sites
...erve University in Cleveland have evidence linking chronic inflammation in the prostate to a greater risk of .../or digital rectal examinations (DRE) suggest that chronic inflammation may be a significant risk factor in the development of prostate cancer. While connecti...How nice, brown rice: Study shows rice bran lowers blood pressure in rats
...isease. But the drugs can also carry side effects: chronic cough, allergic reactions, dizziness, even kidney problems. What if some component of our diet could work in similar fashion, with few or no side effects? Researchers at Tohoku University and Japan’s National Research Institute of Brewing demonstrat......cess. Fontana says, for example, that low-grade, chronic inflammation seems to mediate aging. Overweight and obese people tend to have higher levels of inflammation than lean people, so it makes sense that losing weight might increase average lifespan by lowering the risks of some age-related diseases, suc...Just the expectation of a mirthful laughter experience boosts endorphins 27 percent, HGH 87 percent
...wing a favorite funny video can offset symptoms of chronic stress, which can suppress various components of the immune responses, particularly those related to anti-viral and anti-tumor defenses. In addition, there appears to be a rebalancing of the Th1/Th2 immune response which suggestively could lead to re...New McGill research shows mice capable of empathy
...that social interaction plays an important role in chronic pain behaviour in humans," Dr. Mogil said, "then the mechanism underlying such effects can now be elucidated; why are we so affected by those around us?" Dr. Mogil, the E.P. Taylor Professor of Pain Studies at McGill, is a repatriated Canadian who ...New human retrovirus originated in mice
...f the defense mechanism; and other factors such as chronic inflammation may play a more direct role in the ca...he soil in which cancer arises." He added that the chronic inflammation from infection of stromal tissues may play a role in triggering such cancers. DeRisi o...Johns Hopkins lab scientists tame overactive CF protein
...e pancreas and the lungs, leading to malnutrition, chronic lung infections and lung damage. Cells have a built-in quality-control machinery called ERAD (endoplasmic reticulum-associated degradation), which chemically "marks" defective proteins for destruction and sends them to the cell's waste-disposal comp...UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery
...estore the gut mucosal immune system in those with chronic infections," Dandekar said. "In these patients the...treated within the weeks of exposure to those with chronic infection. They discovered that newly infected patients had fewer signs of inflammation at the begin......ms of poorly understood conditions like asthma and chronic pulmonary obstructive disease, leading to better treatments. ...