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Tag: "chronic" at biology news

Study shows interruption of antiretroviral therapy increases risk of disease and death

...etroviral therapy. As HIV/AIDS has evolved into a chronic disease without a cure, lifelong antiretroviral therapy has become the norm. Lifelong therapy, however, can be difficult to adhere to as well as expensive. For these reasons, there has been a concerted research effort to test treatment interruption s...

A new jump start for aging blood vessels

...ck and destroy tumor cells but can also exacerbate chronic inflammatory diseases. To date, no studies have i... of blood pressure. Second, blocking TNFa via chronic etanercept treatment decreased cell death in aged vessels, demonstrating that increased TNFa levels ...

UGA scientists unravel 'molecular inch-worm' structure of walking-pneumonia bacterium

...niae infections affect millions worldwide, causing chronic bronchitis and atypical or "walking pneumonia," a ...argets and therapies to stop walking pneumonia and chronic bronchitis infections in their tracks. Since the organelle is involved in colonization of epitheli...

Development of gene therapy

...ple in treating adenosine deaminase deficiency and chronic granulomatous disease. There are also initial indi... point to the efficacy of gene therapy in treating chronic lymphatic leukaemia and haemophilia B. But successes in clinical testing come with their share of se...

Five new technologies that promise to transform medicine

...rom the resizing of his wardrobe. Patients with chronic diseases who need regular medication will benefit from a miniature implant that monitors and transmits data on heart and breathing rates, blood pressure, and blood sugar levels. And further into the future are links smart pumps that, when signalled, ...

New biologic treatment for tennis elbow may replace surgery for chronic sufferers

...investigation of this novel biologic treatment for chronic severe elbow tendonitis in patients who have simply 'flunked out' of other treatments," says Dr. Mishra. "Ninety-three percent of patients in our study did well, which is as good a result as patients who have tendon surgery." "There is very litt...

Search on for treatment of slow-healing wounds

...ring a $2.9 million grant to find new ways to heal chronic wounds. The money will allow the center to fund ...r its investigation into the role biofilms play in chronic wounds. The money will be distributed over four years. Biofilms are bacteria that grab onto a sur...

New biochip helps study living cells, may speed drug development

...ving ion channel malfunction, such as epilepsy and chronic pain. About 15 percent of the drugs currently in development affect the activities of ion channels, he said, and their development is limited by the slower pace of current technology. The biochip would allow researchers to generate more data in a sho...

Gene therapy for hereditary lung disease advances

...lung damage occurs. Shortness of breath, wheezing, chronic cough and recurring chest colds are signs of the disease. It is important that alpha-1 patients avoid cigarette smoke, said Mark Brantly, M.D., a professor of medicine and molecular genetics and microbiology at UF's College of Medicine who develop...

Cigarette smoking impedes tendon-to-bone healing

... to 90 percent, depending on the size of the tear, chronic nature of the injury and the age of the patient, among other factors. "Especially during the first six weeks after surgery, tissue may be vulnerable to re-injury," says Leesa M. Galatz, M.D., first author of the study and assistant professor of or...

Dragonfly's metabolic disease provides clues about human obesity

...abolic disorders are known to be associated with a chronic inflammatory response, thought to be triggered by ...DS patients, with compromised immune systems, have chronic problems with Cryptosporidium (a protozoan parasite closely related to the one found in dragonflies)...

Brains can recover from alcoholic damage but patients should stop drinking as soon as possible

...at the brain can recover from the toxic insults of chronic alcoholism and substantiate the early measurable benefits of therapeutic sobriety. However, they also suggest that prolonged dependence on alcohol may limit rapid recovery from white matter brain injury. "Modern neuroimaging enables us to monitor ...

Effective HIV control may depend on viral protein targeted by immune cells

...erefore, the findings of this study, which reflect chronic HIV infection, might not apply in situations in which vaccination generates an immune response before infection occurs. "The possibility that there may be fundamental differences between the impact of Gag and non-Gag CD8 responses on the ability...

Pair of microRNA molecules controls major oncogene in most common leukemia

...ncogene responsible for a dangerous form of B-cell chronic lymphocytic leukemia (B-CLL), the most common huma...bitors might work as a future treatment for B-cell chronic lymphocytic leukemia, he said. These molecules could also be combined with 12 other miRNAs known to ...

Pleasure and pain: Study shows brain's 'pleasure chemical' is involved in response to pain too

...It may also yield clues to why some, but not other chronic pain patients may be prone to developing addiction...d use of opioid painkiller drugs among people with chronic pain. ...

Common cold virus leads to death in lung transplant patients

...rland, and 13 associates assessed the incidence of chronic rhinovirus infection and its potential clinical im...hinovirus," said Dr. Kaiser. "Two of the three had chronic upper respiratory tract infections. All three had relapsing lower respiratory infections, and two su...

UCSD researchers create roadmap to integrin activation

...e of the risk of serious bleeding complications in chronic use. In sharp contrast, drugs such as clopidogrel... two examples of antithrombotics that work well in chronic administration and are widely used for this purpose. "Drugs such as aspirin and clopidogrel work in...

New mechanism underlying pain found

...in. The clearer understanding of the root-cause of chronic neuropathic pain, and the preclinical validation of new targets for pharmaceutical therapies shown in this research, together present an opportunity for the development of new ways to treat the severe pain associated with such common conditions or di...

Antioxidant protects against lung damage in silicosis

...ct tissue injury), become elevated in the lungs of chronic silicosis patients and could represent a new treat... periods. The study included 27 male patients with chronic obstructive pulmonary disease and 27 healthy male volunteers as controls. The investigators also stu...

UCSD researchers discover internal compass of immune cell

...nflammatory bowel diseases, asthma, and many other chronic inflammatory diseases," said Junger. Conversely, drugs that boost these amplification systems and the internal compass could be used to coax neutrophils to migrate to infected wounds to improve wound healing. ...

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