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Tag: "chronic" at biology news

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...y invited three of the world's foremost experts on chronic lymphocytic leukemia (CLL) to write an authoritati... theories about the development and progression of chronic lymphocytic leukemia require revision. With new molecular and protein markers now identified, patien...

Scientists Replicate Hepatitis C Virus in Laboratory

...cent of acute hepatitis cases, 60 to 70 percent of chronic hepatitis cases, and up to 50 percent of cases of cirrhosis, end-stage liver disease, and liver cancer. Almost 4 million Americans, or 1.8 percent of the U.S. population, have antibodies to HCV indicating ongoing or previous infection with the virus....

Scientists detect probable genetic cause of some Parkinson's disease cases

... completing other simpletasks. The disease is both chronic and progressive. Incidence of thedisease increases with age, with an average onset at about 60 years....

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...andcertain cancers and develops during a number of chronic diseases, theresearchers said.Until now, however, a cell's response to iron deprivation was poorlyunderstood. In the Duke study, Thiele and his Duke colleagues at theSarah W. Stedman Nutrition and Metabolism Center demonstrated that theactivity of mo...

Enzyme allows B cells to resist death, leading to leukemia

B cell chronic lymphocytic leukemia (B-CLL)is the most common leukemia in adults and is characterized by theprogressive accumulation of mature B lymphocytes in the blood, bonemarrow, and lymphatic tissues. It is believed that in the early stagesof disease, B-CLL is...

Studies reveal methods viruses use to sidestep immune system

...ed to shut down HCV replication. Hepatitis C is a chronic disease that affects 4 million people in the United States, making it the nation's most common blood-borne infection. It is transmitted primarily through intravenous drug use, blood transfusions or blood products, as well as through sexual contact an...

Alcohol's effects on gene expression in the central nervous system

...chniques confirmed earlier reports indicating that chronic alcohol exposure/withdrawal differentially alters ...ht into cellular changes that occur over time with chronic alcohol drinking and repeated withdrawals." Collectively speaking, added McBride, findings presente...

The very unexpected life and death of a leukemic cell

B cell chronic lymphocytic leukemia (CLL) is an incurable disease...urements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells View the PDF of this article at: https://www.the-jci.org/press/2340...

Boosting HIV screening can increase survival and is cost effective

...commonly employed screening interventions in other chronic conditions, including breast cancer, colorectal cancer, diabetes and hypertension. Paltiel said that even in settings with HIV infection levels similar to the U.S. general population, one-time screening could deliver excellent return on investment. ...

Asthma gene clusters identified

...e of asthma," she said. Asthma is the most common chronic disease of childhood affecting 20 million Americans, according the Centers for Disease Control. Experts know that environmental factors can lead to asthmatic conditions in children, but they also know that genetics contributes to susceptibility. Ther...

Potential treatments for neurofibromatosis

... leave its patients miserable and debilitated with chronic itching or pain from disfiguring tumors. Infants affected by the disease face possible paralysis or damage to the brain and other organs. The disease frustrates doctors because there's no effective treatment even though the responsible gene was iden...

Norovirus, AIDS vaccine and Hepatitis Virus

... One class of interferons (alpha) is used to treat chronic infection with HBV and HCV. There is a vaccine ava... may be therapeutically useful in the treatment of chronic HBV or HCV infection." (M.D. Robek, B.S. Boyd, F.V. Chisari. 2005. Lambda interferon inhibits hepat...

Chemists identify immune system mechanism for methamphetamine binges

...confirmed in human studies, could help explain why chronic users go on long binges with the illicit drug, also known as speed. The study could lead to new treatments for the drug's addiction, they say. Recent studies by others have documented the drug's apparent ability to suppress the immune system, making...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...and deer, which suffer from a prion disease called chronic wasting disease. Surewicz stresses, however, prion infection between species is still rare. "Fortunately, transmission by eating is very ineffective. There have been hundreds of thousands of bovine spongiform encephalopathy cases, for example, and l...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

... rather invest in compounds aimed at patients with chronic conditions such as high cholesterol or diabetes, not in drugs designed to be used for a week or two and then stopped once an infection clears, he said. Now UF researchers have devised a patent-pending method that combines testing of various drug con...

FDA Clears the Way for Generic Versions of Transdermal Patches to Treat Chronic Pain

...stem) used to treat patients suffering from severe chronic pain that cannot be managed with alternative analg...90. It is currently approved for the management of chronic pain in patients who require continuous opioid analgesia for pain that cannot be managed by acetamin...

Scientists Propose Sweeping Changes to Naming of Bird Neurosystems to Acknowledge Their True Brainpower

...stem) used to treat patients suffering from severe chronic pain that cannot be managed with alternative analg...90. It is currently approved for the management of chronic pain in patients who require continuous opioid analgesia for pain that cannot be managed by acetamin...

Rare surgery performed to remove pancreas, prevent diabetes

...s pancreas to eliminate constant, severe pain from chronic pancreatitis. The patient, Leonard Stewart, 47, o...e pancreas, directs a clinic for the management of chronic pancreatitis, is chief of gastrointestinal surgery and co-director of the UAB Pancreaticobiliary Cen...

Strongest proof yet found for prion hypothesis

...iant Creutzfeldt-Jakob Syndrome, scrapie, kuru and chronic wasting disease. This controversial "prion hypothesis" was proposed by Stanley Prusiner in 1982, and led to Prusiner receiving the Nobel Prize in Medicine in 1997. Until now, however, scientists have been unable to confirm its validity by causing a ...

Emergence of cancer as major cause of childhood death in developing countries is not being adequately addressed

...n and many international charities don’t even list chronic diseases, including cancer, as health priorities on their agendas.?/p> The increasing pediatric cancer death rate in countries with limited resources is especially tragic because strategies exist that could be used to ensure wider access to effec...

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