Researchers publish first marsupial genome sequence
...ess lifestyle, often shuttling themselves from one chromosome to another," said the study's first author Tarjei Mikkelsen, a Broad Institute researcher. "It is now clear that in their travels, they are disseminating crucial genetic innovations around the genome." Other important findings to emerge from the ...Baumann Lab defines proteins that distinguish chromosome ends from DNA double-strand breaks
... paper offering insight into the way cells protect chromosome ends from misguided repair. Published in tomorro...ional manner." It has long been understood that chromosome ends are distinct from DNA double-strand breaks and that the cellular machinery that repairs DNA bre...Genetic roots of bipolar disorder revealed by first genome-wide study of illness
...ch of the enzyme is produced. The DGKH gene is on chromosome 13. Several other genes detected in the study produce proteins involved in this and other biochemical pathways thought to play a role in bipolar disorder. Understanding the effects that variations of these genes have on brain-cell function could ...New technique will produce a better chromosome map
...Nature Methods. Fruit flies are well suited for chromosome studies because some of their cells contain gigant...uide to the chromosomes. Traditional methods of chromosome preparation have limited usefulness for those hoping to sort out how the bands and interbands relate...Understanding why C. difficile causes disease -- it's hungry
... is studying a five-gene region of the bacterium’s chromosome known as the tcd locus. Two of the genes code for the toxins the bacterium produces that cause disease and a third gene codes for a protein that makes a hole in the organism’s cell envelope to let the toxins out. The last two genes are of greatest ...Modified mushrooms may yield human drugs
... cell, and integrates the introduced gene into the chromosome of the mushroom. Next, the researchers exposed the mushroom cells to hygromycin. The antibiotic kills all the normal cells, separating out those that have been genetically altered for resistance. The test demonstrates that if a second gene, in......gnposts.” In the new method, loxP is inserted in a chromosome on one mouse, and in a different position on the same chromosome in a second mouse, which also has a gene named Cre in its cells. When the mice are bred, an offsprin...Exploring the dark matter of the genome
...ot. Centromeres play a crucial role in controlling chromosome duplication during cell division. Telomeres are a ...at one intensively studied and puzzling problem in chromosome biology will benefit enormously from the new findings: epigenetics -- the inheritance of traits and ...Genetic factors are linked to fever following smallpox vaccination
...usters in the interleukin-1 (IL-1) gene complex on chromosome 2 and the interleukin-18 gene on chromosome 11. The interleukins, and especially the IL-1 gene complex, are groups of molecules associated with...Physicist cracks women's random but always lucky choice of X chromosome
...s always lucky. Human males have both a X and a Y chromosome but females have two X chromosomes. This means tha...de gene called XIST which, if activated, seals the chromosome behind a barrier of RNA preventing the activation of any other gene. Researchers believe that this s...Researchers shed light on shrinking of chromosomes
...ell division and helps preventing fatal defects in chromosome separation. Now researchers from the European Mole...ology Laboratory (EMBL) for the first time tracked chromosome condensation in mammalian cells over the entire course of cell division. In this week’s advanced onl...Identified main genetic variants involved in response to HIV
.... These variations are located in the short arm of chromosome 6 in genes controlling HLA-B and HLA-C molecular s...pates in viral replication, and is also located in chromosome 6. Genetic variants associated to genes encoding HLA-B and HLA-C molecular systems would explain u...