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Tag: "chromosome" at biology news

Housecat-sized Siberian tiger cubs get collared

...y pregnancy are dependent on a cluster of genes on chromosome 19 called the Luteinizing Hormone/Chorionic Gonad...2,000-4,000 live births and involves a deletion on chromosome 22. The deletion is mediated by rare repetitive sequences that flank genes crucial for proper devel...

Study hints at role of stem cell genes in testicular, breast cancers

...e genes -- NANOG, STELLAR and GDF3 ?are located on chromosome 12, at a site designated 12p13. Because seminoma...ture, and have duplications in genetic material on chromosome 12p13 that are associated with invasive seminoma (though no genes have been linked to the malignancy...

Customized gene chip provides rapid detection of genetic changes in children's cancer

...ory previously established that LOH in a region of chromosome 11 allows aggressive neuroblastoma to take hold. The new microarray can detect such gene defects on chromosome 11 and other genetic regions implicated in neuroblastoma. Microarrays are silicon chips that contai...

Plant wounds trigger bacteria

...plasmid is a ring of DNA that is separate from the chromosome and is not essential for the bacterium's survival but is required for tumor growth. The plasmid can also transmit itself from one bacterial cell to another when the two cells touch one another, in bacterial congress. The plasmid recognizes organic c...

Building a better mouse model of lung cancer: FHIT counts

... one of several tumor suppressor genes residing on chromosome 3 in humans that, when working normally, keep any ...ond tumor suppressor gene, VHL, which also sits on chromosome 3 in humans. (Mice with loss of both copies of VHL do not survive.) "We chose this gene because VHL...

Normal chromosome ends elicit a limited DNA damage response

...s repair machinery is designed to fix. But mending chromosome ends, or telomeres, would set the stage for the de..., they wondered, why didn't the presumably exposed chromosome ends trigger a DNA damage response? Turns out they do, at least to a limited extend. "During a s...

A little telomerase isn't enough

...een the health of stem cells and the length of the chromosome ends within them. Chromosome ends, or telomeres, ...fabric from fraying. Each time a cell divides, its chromosome ends get a little shorter, and eventually the cell can no longer divide because its critical genetic...

Delaware scientists make significant advance in study of small RNAs

...ts to examine any gene or region of an Arabidopsis chromosome for matches to small RNAs. Science is a prestigious journal published by the American Association for the Advancement of Science. The paper's first and second authors are Cheng Lu, a molecular biology postdoctoral researcher, and Shivakundan Singh T...

Double trouble: Cells with duplicate genomes can trigger tumors

...only have too many centrosomes and a near triploid chromosome number (one and a half times the normal chromosome content). Because the cells with extra chromosomes and centrosomes are biologically different from n...

Scientists pinpoint inflammation gene

...researchers has discovered that a specific gene on chromosome 15 regulates inflammation, a finding with implications for a wide range of disorders, including cancer, cardiovascular disease, diabetes, obesity, Alzheimer's, and infections. The findings are published in the October 9 online issue of Nature Geneti...

Cells from amniotic fluid used to tissue-engineer a new trachea

...men elect to have amniotic fluid drawn to test for chromosome defects, the procedure known as amniocentesis. And when a prenatal ultrasound exam reveals fetal malformations, amniocentesis is usually recommended. Complications are rare. "In many cases, the amniotic fluid is collected anyway," says Fauza. "It's ...

Looking for the genes that affect a person's level of response to alcohol

...p; Experimental Research has found that a gene on chromosome 10 ?in particular, the KCNMA1 gene ?is potentially...mosomal regions. Results indicate that an area on chromosome 10 is potentially linked to LR, in particular, the KCNMA1 gene. These results are particularly inte...

Gene increases risk of tuberculosis

... study found that a particular region on the human chromosome 17 was associated with increased risk of developin... a protein called MCP-1 (the MCP-1 gene resides of chromosome 17). The genetic change was a tiny one, with the DNA sequence differing by only a single nucleotide...

Researchers show key protein necessary for normal development of red blood cells

...n humans, there are four globin genes clustered on chromosome 11 in the order in which they are "turned on" or expressed. These genes include the epsilon-globin gene, two gamma-globin genes and the beta-globin gene. Lloyd said that during fetal development, the embryonic epsilon-globin gene is active first, fol...

New methods offer insight into regulatory DNA

...me regions. The second was 35million base-pairs of chromosome 21 sequence: three copies of chromosome 21 lead to Down Syndrome. The third was a region of chromosome 20 ?10 million base-pairs ?that is kn...

Scientists fetch useful information from dog genome publications

...amount of information. "We present a new model of chromosome evolution that accounts for the extensive breakage...onsistent with our finding that a variant on the X chromosome plays a role in skeletal size determination." ...

Dog genome sequenced

...amount of information. "We present a new model of chromosome evolution that accounts for the extensive breakage...onsistent with our finding that a variant on the X chromosome plays a role in skeletal size determination." ...

Patterns in genome organization may partially explain how microbial cells work

...y to determine if a particular gene or area of the chromosome was segregated in any particular way inside the ce...ngth of a variety of periodicities associated with chromosome position. Just as the wavelet analysis identified significant increases in sea surface temperatures;...

Researchers map of genetic variations implicated in disease

...mplex (MHC) consists of hundreds of genes on human chromosome 6 that are important in most autoimmune conditions...y far the largest genetic contribution by a single chromosome region. For example, the MHC accounts for at least 30% of the familial aggregation in type 1 diabete...

Three new species of lemurs identified

... been identified from morphological differences or chromosome profiles ?the methods usually used to define speci...ied individual lemurs on the basis of either their chromosome profile, called a 'karyotype', or the sequence of the mitochondrial cytochrome b gene. The team anal...

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