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Tag: "chromosomal" at biology news

First frozen egg baby born in Canada

...ous abortion increases significantly. The risks of chromosomal abnormalities, such as Down's syndrome, are also higher in babies produced by older women. Finally, current egg donor programs require matching the menstrual cycle of egg recipients; this problem can be eliminated with egg freezing. ...

Beyond lithium for bipolar disorder

...d PACAP in the brain and is known to be close to a chromosomal region that genetic studies have shown to be associated with a higher risk of bipolar disorder. PACAP protein is found throughout the central nervous system, said the researchers. They cited studies demonstrating that mice in which the gene is knock...

Alcohol's effects on gene expression in the central nervous system

...ing has also been used to identify chromosomes and chromosomal regions that influence alcohol drinking and response to alcohol." # Intracranial self-administration of ethanol into the posterior ventral tegmental area (VTA) of alcohol-preferring rats produced results suggesting that the reinforcing effects of al...

Needling Chromosomes Reveals Cell Division Secret

...es chromosome imbalances thatcan lead to cancer or chromosomal abnormalitiesthat cause birthdefects."According to Nicklas, it was known that the two sister chromatidsadhered to one another and released at the appropriate time during celldivision. However, that understanding was based on biochemicalexperiments th...

Yale Scientists Find MicroRNA Regulates Ras Cancer Gene

...ural and separately transcribed RNA that maps to a chromosomal region associated with lung cancer as a regulator of Ras expression. DNA of plants and animals contains sequences encoding microRNAs, important regulators of development, that control processes determining cell type and cell death. "The let-7 micro...

Novel Enzyme Shows Potential As An Anti-HIV Target

... copy its RNA genome into DNA and infiltrate human chromosomal DNA. Once the virus is integrated (now called a provirus), its genes can be transcribed. Adept as HIV is in exploiting its host’s molecular resources, the virus can’t establish a foothold without the services of its skeleton crew. The HIV transcript...

Breakthrough Microarray-based Technology for the Study of Cancer

...nomic hybridization (CGH),which undergoes dramatic chromosomal changes, including loss,duplication and the transl...y allows for the use of total genomic DNA todetect chromosomal changes across the entire genome. The Platformenables amplification or non-amplification of total ge...

New binding target for oncogenic viral protein

...rotein called Fbw7. The Fbw7 gene is located in a chromosomal region that is deleted in up to 30% of human tumors. "Fbw7 is itself an important tumor suppressor which makes it an attractive choice for inactivation by Large T," explained Dr. Markus Welcker, the study's first author. The research appears as the ...

Man and mouse share genome structures

...genomes, finding similar patterns along equivalent chromosomal regions, even where the underlying DNA sequences are different. Bernstein and Schreiber began to develop the analytical techniques several years earlier, working with the smaller yeast genome. To investigate the much larger human genome, they collab...

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