To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
...ed tuberculosis (TB) and typhoid fever, controlled cholera and gonorrhea, reduced staphylococcal dysentery, and lowered the incidence of many other pandemic bacterial infections. These antibiotics are basically natural chemicals (or derivatives of natural chemicals) produced by other bacteria or fungi in the...Active Vaccine Prevents Mice From Developing Prion Disease
... several animal vaccines and in human vaccines for cholera and typhoid fever. Among mice vaccinated prior to prion exposure, approximately 30% remained alive and symptom-free for 500 days, according to the study. By comparison, mice that didn't receive the vaccine survived only an average of 185 days, and al...Say what? Bacterial conversation stoppers
...eria that mixes with E. coli in human guts. When cholera bacteria sense a quorum, they turn off their toxin...uelched much of the quorum-sensing response of the cholera bacteria, although the effect was not as dramatic as with the marine bacteria. "The real take-home ......le, others have shown that the bacteria that cause cholera express protein toxins only when they detect bile salts in the host's intestine. It will be interesting to see whether those bacteria also increase the replication of the genes necessary for disease." The bacterium A. tumefaciens employs a large t...Small molecule inhibitor of cholera discovered
...Gulf states and Guatemala have raised the risks of cholera outbreaks, researchers at Harvard Medical School h...ve identified a new type of antibiotic against the cholera bacteria. While traditional antibiotics kill bacteria outright by interfering with processes essenti...Effective, safe anthrax vaccine can be grown in tobacco plants
... and hepatitis, and improving vaccines for plague, cholera and other bioterrorism agents. Daniell is developing a new technology that would enable vaccines to be administered orally and allow effective and less expensive treatments to be more accessible worldwide. He believes fruits and vegetables such as c...Scientists design potent anthrax toxin inhibitor
...nique could be used to design better therapies for cholera and other diseases," says NIH Director Elias A. Ze...researchers also created a polyvalent inhibitor of cholera toxin that functioned well in test-tube experiments. In the next phase of their research, Drs. Kane...Anthrax inhibitor counteracts toxin, may lead to new therapeutics
...g strategy by designing a polyvalent inhibitor for cholera toxin, demonstrating that this approach also could be used successfully to enhance the potency of polyvalent inhibitors directed to this target and, they suggest, others. They note the work also could be useful for creating specific target recognitio...U-M researchers take new approach to defeating Gram-negative bugs
...er-known Gram negatives are salmonella, gonorrhea, cholera and meningicoccal meningitis, along with the bacteria that caused the black plague. Woodard and his collaborators worked on E. coli in part because it is one of the more common Gram-negative bacteria, and it is considered by researchers the gold sta...Bacteria have their own immune system protecting against outside DNA
...reign DNA, bacteria that cause typhoid, dysentery, cholera and plague have evolved from harmless organisms into feared pathogens," explained Dr. William Navarre, a senior fellow at the UW and primary author of the study. "This research gives us an explanation of how pathogenic bacteria have evolved over mill......day, testing air, water or food for pathogens like cholera and dysentery must be done one pathogen at a time....o humans by themselves. But the gene producing the cholera toxin is harmful. These genes serve as good markers for detection. Hashsham's device will be designe...