Cardiologist's 'living chip' changes science of disease monitoring
...ceutical companies, which could use the biological chips to test potential drugs in the lab more quickly and accurately. In later generations, the chip ultimately could command implanted devices ?for example, a wireless defibrillator/pacemaker or an insulin pump ?to take action to correct a detected abnorm...MIT designs portable 'lab on a chip'
...e sample to a lab and waiting for the results. The chips are so small and cheap to make that they could be designed to be disposable, Bazant said, or they could be made implantable. Potential applications are not limited to military use - imagine going to a doctor's office and getting test results immedi...World's smallest cancer detection device
...rs, where they would remain for days or weeks. The chips would report remotely to scanners that would "read" them on the nature of the cells that infiltrate them--in particular, on whether metastatic cells are present that would call for more aggressive cancer therapy. In 2005, Einstein formed an allianc...Taking 'chips' to the next level of gene hunting
...cademy of Sciences. The most commonly used gene chips are glass slides that have arrayed on them neat gr... be done on an ever larger scale," says Boeke. The chips his team currently uses cost about $400 per experiment. If the amount of information can be quadrupl...NHGRI aims to make DNA sequencing faster, more cost effective
...d to construct high-density sample arrays on glass chips and to run sequencing by synthesis reactions on them in an automated, high-throughput fashion. ...Meeting the ethanol challenge: Scientists use supercomputer to target cellulose bottleneck
...erial, from corn stalks left after harvest to wood chips from papermills and fast-growing weeds. "Our simulations have given us a better understanding of the interactions between the enzyme complex and cellulose at the molecular level -- the computer model showed us how the binding portion of this enzy...Gene hunters close in on Lou Gehrig’s disease
...ll 555,352 SNPs in the genome of each subject. SNP chips are glass slides that resemble computer processor chips. They’re coated with tiny beads that “read?the SNPs scattered throughout the human genome. The researchers found 34 genetic variants that ALS patients were more likely to have compared to nor...Gene chips forecast ecological impacts of climate change
...re stress alone. Data presented will show how gene chips and other molecular approaches can assist in understanding how marine invertebrates are responding to the climate-change related multiple stressors in the world's oceans. Sunday, Feb. 18, 2007, 3:30 PM - 5:00 P.M. Hilton San Francisco, Ballroom ...Elucidation of the genome for diabetics with DNA chips
...almost half a million DNA mutations. Each of these chips can be used to dissect the entire genome of an ind...results from the analysis of very high-density DNA chips ?the first in the world for a common disease like DT2 ?demonstrate the validity of this approach. Th...Major gene study uncovers secrets of leukemia
...t. Jude team used microarrays, postage-stamp-sized chips that contain DNA fragments, which allowed researchers to investigate more than 350,000 markers called single nucleotide polymorphisms. Single nucleotide polymorphisms are individual variations in the DNA that are spaced across the human chromosomes. ...Genome sequencing reveals key to viable ethanol production
...m plant materials such as the corn stalks and wood chips is challenging because the plants?cellulose is a very tough substance to break down, making for an inefficient process. Wu’s technique may prove much more effective than traditional methods. Instead of using separate steps to break down biomass int...Technique monitors thousands of molecules simultaneously
... its behavior. The electrochemically addressable chips being used represent a new environment for synthetic organic chemistry, changing the way chemists and biomedical researchers make molecules, build molecular libraries and understand the mechanisms by which molecules bind to receptor sites. "We beli......ing larger sample populations, more powerful array chips that can distinguish more genetic markers, and more sophisticated methods of analyzing the data....