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Tag: "chemotherapy" at biology news

Dealing deadly cancers a knockout punch

...ing ability of reovirus plus cisplatin, a standard chemotherapy agent, in a mouse melanoma model that included bot...in can improve the anti-tumor activity of standard chemotherapy agents in advanced cancer patients without causing additional toxicity," said Dr. Karl Mettinger, Ch...

DNA repair proteins monitored at double-strand break

...ability to repair double-stranded breaks caused by chemotherapy or radiation. It could also suggest new strategies for enhancing repair of double-stranded DNA caused by radiation, natural oxidants in food or the body and other toxins that can cause disease and aging. "Prior to this work, there was no practical...

Targeting sugar on blood vessels may inhibit cancer growth

...of vasculature. The drug has been used along with chemotherapy in humans to successfully inhibit the growth of tumors in colon and lung cancers. "If novel drugs can be developed to target tumor heparan sulfate, we might be able to make a leap in cancer-fighting therapies, because several molecules critical to...

Cancer patients monitor fatigue in real time

...ressing symptoms cancer patients experience during chemotherapy and radiation treatment, but it's difficult for health care professionals to accurately assess its severity. Nurse researchers at the University of Illinois at Chicago are studying fatigue in cancer patients undergoing stem cell transplants using a ...

Surprising origin of cell's internal highways

...y altering microtubule dynamics. "Many classic chemotherapy strategies affect microtubules, although it's not quite clear how these drugs influence cancer cells differently than normal cells," said Kaverina. "Both microtubule regulation of proliferation and microtubule regulation of migration and invasion pro...

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents

...of Pittsburgh School of Medicine suggests that for chemotherapy to be truly effective in treating lung cancers, for example, it must be able to target a small subset of cancer stem cells, which they have shown share the same protective mechanisms as normal lung stem cells. They are presenting this ground-breaking...

Women well informed about breast cancer, yet lacking knowledge about current treatments

...o the survey, nearly all respondents were aware of chemotherapy and radiation. However, fewer than one out of four had heard of newer therapies such as aromatase inhibitors or monoclonal antibodies, nor were they informed about their benefits. Doctor-patient dialogue is vital If diagnosed, the majority o...

U-M researchers discover gene switched off in cancer can be turned on

...f time, which is unlike older and more traditional chemotherapy agents. Even if these new targeted therapies don’t cure the cancer, we can at least have long-term survival,” he adds. ...

Studies to find better ways to preserve human eggs, ovarian tissue under way

...cers often leaves women infertile because systemic chemotherapy and more focused radiation therapy, designed to kill rapidly spreading cancer cells, also can destroy dynamic reproductive tissue. “I don’t think when you are faced with the reality that you may die, your fertility is the most important thing you...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

...rus. For most patients whose cancer is inoperable, chemotherapy is one of the main treatment options, and still th...andomized controlled trial comparing two different chemotherapy regimens. One hundred and seventy patients (92 percent) had evidence of HBV infection. Of these, 12...

Blood test may help signal tumor's remission, return in throat cancer patients

... a useful tool for monitoring the effectiveness of chemotherapy and radiation treatment in people with advanced th...cline in several cancer-related proteins following chemotherapy and radiation treatment were more likely to remain in remission, while those who experienced a large...

St. Jude study solves mystery of mammalian ears

...causes for hearing loss, including side effects of chemotherapy for cancer. One strength of St. Jude is that researchers have the ability to ask some very basic questions about how the body works, and then use those answers to solve medical problems in the future.” The long-standing argument centers around oute...

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