chemotherapy 2 7

Tag: "chemotherapy" at biology news

Math model predicts cancer behavior

...Quaranta said. The findings suggest that current chemotherapy approaches which create a harsh microenvironment in the tumor may leave behind the most aggressive and invasive tumor cells. "In the immediate term we may be diminishing tumor burden, but the long term effect is to have a much nastier tumor than th...

Radiation after surgery doubles survival time for some lung cancer patients

...and spine ?who receive radiation after surgery and chemotherapy live twice as long as patients who do not receive ...tudy, ANITA 1, which examined the effectiveness of chemotherapy after surgery in 840 non-small cell lung cancer patients and found that additional chemotherapy afte...

Science researchers genetically transform immune cells into tumor fighters

...tiplied these cells in the laboratory. After using chemotherapy to clear out a patient's old T cells, the researchers repopulated the patients' immune systems with these new fighters. But some people with melanoma don't have these tumor-fighting T cells, and in other types of cancer it's difficult to identify T...

Gene key to taste bud development identified

...urgery for correction. Cancer patients receiving chemotherapy or radiation therapy often report the loss of taste during treatments. These therapies target cells that are dividing, making them effective in killing cancer cells but also causing the unwanted side effect of killing taste buds. When the cancer trea...

St. Jude announces breakthrough in eye cancer treatment

... the first example of local delivery of a targeted chemotherapy drug for any childhood cancer, Dyer said. Targe...n the most effective known combination of standard chemotherapy drugs. "The findings suggest that this treatment not only could offer children with retinoblastoma...

Common cold virus may kill breast cancer cells

...ells ?this would be an improvement on conventional chemotherapy and radiation treatment, which also impact on normal body cells. "In theory, the virus is able to selectively target and destroy many different types of cancer cells, including breast cancers, whilst leaving normal cells unaffected," she said. Deb...

Tumor cells evade death through autophagy

...equently. Autophagy is initiated in tumor cells by chemotherapy and radiation, but it is not known if this contributes to tumor cell death or helps tumor cells survive the anti-cancer therapy. However, in a study using a mouse model of B cell lymphomas, researchers from the University of Pennsylvania have now sho...

Sunshine pill for prostate cancer in 2009

... the advanced stages of prostate cancer along with chemotherapy drugs. Drug makers came up with the idea because ...oved survival rates, 9 months over patients taking chemotherapy drugs (taxotere) alone. 'On average, patients in the advanced stage of the disease survive about 18...

Dual gene therapy suppresses lung cancer in preclinical test

...either of genes or of genes with other biologic or chemotherapy agents. "We certainly hope this approach will be more effective but we also think it's likely to be much less toxic, with fewer side effects, than other types of combined cancer therapy," Roth says. "These genes don't have much effect on normal ti...

Researchers first to map gene that regulates adult stem cell growth

... the stem cell count in cancer patients undergoing chemotherapy and bone marrow transplantation. The rese...ible treatments for patients." One big obstacle chemotherapy patients face is stem cell loss after treatments. This limits the dosage amount and types of chemoth...

Researchers urge monitoring of bone health during chemotherapy

...ication often used to reduce toxic side effects of chemotherapy induced bone loss and helped tumors grow in bone. ...rowth it allows patients to undergo more intensive chemotherapy regimens in which anticancer agents are given at more frequent intervals. Studies have suggested the...

UCSF brain tumor vaccine trial shows promising results

...ociated with traditional cancer treatments such as chemotherapy and radiation therapy. Vitespen has been granted f...or a second opinion after undergoing radiation and chemotherapy elsewhere for treatment of a glioma. At UCSF she learned that part of the tumor was still present, ...

Destructive enzyme shows a benevolent side

...ress. The response might help cancer cells survive chemotherapy and radiation therapy. The study examined a rece... low oxygen (which can occur within large tumors), chemotherapy or radiation therapy. The study, led by researchers at Ohio State University's Comprehensive Canc...

Molecular differences between early and advanced melanomas could provide new drug targets

...ow downward, the tumors become highly resistant to chemotherapy and radiation and the five-year survival rate falls rapidly, to 64 percent if the disease has reached the lymph nodes and 16 percent if it has spread to other organs. The discovery of Akt's significant role in the progression of melanomas was made...

Breakthrough vaccine to treat chemo-resistant ovarian cancer

...te a patient-specific vaccine and is combined with chemotherapy delivered directly into the abdominal cavity. Ovarian cancer, one of the hardest cancers to detect in the early stages, is a very complex disease that is often resistant to chemotherapy. Cancer Treatment Centers of America will offer this new tr...

Study calculates patient time costs associated with cancer care

...time spent at physician and emergency room visits, chemotherapy treatments, radiation therapy, hospitalizations, outpatient surgeries, and imaging procedures. They then estimated how long each patient spent traveling to, waiting for, and receiving care. The net costs were calculated using a dollar value of $15.23...

Gut research yields new anti-cancer approach

...ugh some of the same mechanisms as the blockbuster chemotherapy Taxol, but with key differences. While studying w...ubule not an option for colorectal cancer, current chemotherapy regimens feature 5-fluorouracil (5-FU) in combination with other chemotherapy drugs (oxaliplatin, ir...

Scientists identify pancreatic cancer stem cells

...ome preliminary research, standard treatments like chemotherapy and radiation may not be touching these cells," said Simeone. "If that is why pancreatic cancer is so hard to treat, a new approach might be to design a drug that specifically targets pancreatic cancer stem cells without interfering with normal stem ...

Researchers wake up viruses inside tumors to image and then destroy cancers

...700 agents until they hit upon Velcade, a targeted chemotherapy drug already approved for use in multiple myeloma. "We were both surprised and lucky," he says. "Velcade is a proteasome inhibitor, but it also induces the lytic cycle thereby activating the TK in the Epstein-Barr virus. Once the TK is activated, we...

Gene thought to assist chemo may help cancer thrive

A gene thought to be essential in helping chemotherapy kill cancer cells, may actually help them thrive. ... Some of the cancer patients had been treated with chemotherapy prior to surgery, and some had not. At this point researchers didn't consider whether the patients a...

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