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Tag: "chemotherapy" at biology news

Preclinical study of a new brain tumor therapy

...for GBM. There are few existing options aside from chemotherapy and surgery to remove the tumor, and it is rare that these treatments stop the cancer from recurring. Given the prevalence of EGFR in cells of other cancer types (such as breast cancer and lung cancer), the approach pioneered in this study may be app...

Combination therapy improves AIDS-related lymphoma outcome

Combining aggressive HIV therapy and chemotherapy significantly improves the survival rates of HIV-p...tive patients on HAART while they are treated with chemotherapy for ARL, oncologists are hesitant to expose HIV patients to hypothetical drug toxicities related to ...

Parents need to be educated about HPV vaccinations for daughters

...ed disease, principally in the form of concomitant chemotherapy and radiotherapy." Professor Kitchener concluded: "HPV vaccines provide hope for major international programmes of primary prevention." ...

Cellular scale drug delivery from the inside out

Delivering a dose of chemotherapy drugs to specific cancer cells without the risk of... only cancer cells could be targeted with powerful chemotherapy drugs such as Taxol or doxorubicin, while the nanospheres inside the normal cells would remain cappe...

BiovaxID?yields 89 percent survival in patients with aggressive non-Hodgkins

...dministered six cycles of dose-adjusted EPOCH-R, a chemotherapy regimen that includes Rituxan® (rituximab). Of th... at least three months after completing their last chemotherapy and Rituxan treatments. Upon the 46-month (3.8-year) follow-up, the overall survival rate was 89%. T...

Light activated anticancer drug targeted to DNA using cisplatin like sub-units

One of the most effective chemotherapy drugs against cancer is cisplatin because it attaches to cancer DNA and disrupts repair. However, it also kills healthy tissue. Many scientists are creating alternative drugs or cisplatin analogs in attempts to find treatments without side effects. O...

Predicting success

...re they are needed. Normally, a material such as a chemotherapy drug crosses into a tissue on the principle of con...e in cancer tissues is at levels that could render chemotherapy ineffective. Their research, which led to the method, was done with MRI equipment similar to that fo...

Chemotherapy gel may fight breast cancer and reduce breast deformity

...e to radiation therapy that would not only release chemotherapy slowly to kill the cancerous cells left behind aft...he researchers encapsulated a common breast cancer chemotherapy drug, doxorubicin, in microspheres, or beads, and then mixed them with a gelatin made of a polymer s...

Nanotechnology may find disease before it starts

...e rest of the body," Rosol said. "The problem with chemotherapy is that the drug affects the whole body, causing a host of problems such as hair loss, diarrhea and anemia." ...

Botox could help target resistant tumors for treatment

...vant to cancer therapy, providing an open door for chemotherapy and radiation treatments, according to a study pub...or perfusion and oxygenation temporarily." While chemotherapy and radiation treatments have remained the standard of care, tumor cells of most cancer types have s...

Predicting chemotherapy outcome

...tients who subsequently responded well to combined chemotherapy and patients who were resistant to the therapy. Th...out before the patients were treated with combined chemotherapy of folinic acid, 5-fluorouracil and irinotecan. Imbeaud and colleagues identified 679 genes that we...

UCLA scientists uncover mechanism of response to targeted therapy

...t kill them." It could be paired with conventional chemotherapy or with another targeted therapy, such as an angio...I-779 would stop the growth of the cancer, and the chemotherapy would be used to kill the cancer cells or the angiogenesis inhibitor could be administered to cut of...

St. Jude projects 90 percent cure rate for ALL

...k the enzyme TPMT are more sensitive to thiopurine chemotherapy drugs and are more likely to suffer damage to the body's blood-producing cells. Evans subsequently discovered the genetic cause and developed a gene-based test that permits clinicians to identify children who should be treated with lower doses of thi...

How can we protect patients with weakened immune systems from influenza?

...ses in children receiving different intensities of chemotherapy for solid tumors and two types of leukemia. Anothe...ed with a novel type of stem cell transplant. Both chemotherapy and stem cell transplants involve suppressing the patients' immune defenses. A third group of patien...

New test to detect rare proteins in blood

...f Her2/neu correlate with a lower response rate to chemotherapy and shorter survival time after relapse. The Greene lab developed mouse models that carry cancer cells overexpressing Her2/neu. When these cells are implanted into animals they form tumors exactly like breast tumors in humans. Using ELISA, the rese...

Can dogs smell cancer?

...mmogram, or CAT scan and had not yet undergone any chemotherapy treatment. During the study, the dogs were presented with breath samples from the cancer patients and the controls, captured in a special tube. Dogs were trained to give a positive identification of a cancer patient by sitting or lying down directly ...

'Shuttling' protein possibly key to resilience of cancer cells

... play a crucial role in cancer's ability to resist chemotherapy and radiation treatment and that also may be invol...ght be developed to target cancer stem cells while chemotherapy or radiation is administered, Hu said. Research findings are detailed in a paper appearing this mon...

Faults in newly discovered breast stem cells may lead to tumours

...st cancer cells have been apparently eliminated by chemotherapy sometimes experience a recurrence of their cancer.... an errant stem-like cell may be more resistant to chemotherapy because it divides more slowly. So while chemotherapy can eliminate the bulk of cancer cells, the tu...

Data published in PNAS show antibodies can be made 10 times more toxic to cancer cells

...noclonal antibodies have important advantages over chemotherapy and small molecule drug treatments for cancer, such as their specificity in targeting tumor cells and low toxicity. There are currently eight approved anticancer antibody products on the market today and many more are in development. Unfortunately, m...

Molecular force field helps cancer cells defend against attack

...ive barrier that deflects damage from radiation or chemotherapy and promotes tumor cell survival. But in laboratory experiments, UF scientists were able to block the union, and the malignant cells died. The findings are opening new avenues of research that could lead to improved cancer therapies, the researchers ...

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