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Tag: "chemotherapy" at biology news

U-M team recovers ancient whale in Egyptian desert

...ke them a less-vulnerable target for radiation and chemotherapy and thus spare normal tissue during high-dose cancer therapy. "Right now in most forms of cancer treatment we're killing off the normal cells long before we're killing off the tumor cells. By inducing metabolic hibernation in healthy tissue we'd at ...

First frozen egg baby born in Canada

...ncer to preserve their fertility before undergoing chemotherapy and radiotherapy, which can cause infertility and premature menopause," says Dr. Lucy Gilbert, Director of Gynecological Oncology at the MUHC. Over the past two years, 16 cancer patients have had their eggs frozen at the MUHC. "Egg freezing also allo...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

...to rebuild the blood system of patients undergoing chemotherapy and radiation for cancer. Opferman completed work ... leukemia from undergoing apoptosis in response to chemotherapy or radiation. This makes the leukemia cells resistant to treatments designed to damage the cell so i...

Two are better than one

...ling. In response, the cell halts growth and, when chemotherapy is used in combination with the immunotherapy, it dies. According to Sela, the study sheds light on the synergy at work in the antibody-receptor therapy system. The results demonstrate that with the right combination of antibodies, receptor degradat...

Discovery may lead to better Candidiasis drug

...ith weakened immune systems caused by antibiotics, chemotherapy or by diseases such as AIDS. Thrush also affects many denture wearers. The condition can be treated with antifungal medication in otherwise healthy people, said Edgerton, but it is difficult to treat in persons with compromised immunity and can be d...

Same-Sex Mating Discovered in a Toxic Fungus

...systems are crippled by immunosuppressive drugs or chemotherapy -- and people with HIV/AIDS. The fungus' global importance as a health threat has therefore risen in parallel with the increased use of such therapies and with the worldwide HIV/AIDS pandemic. In plants and animals, sexual identity is governed by se...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

... with cancer the opportunity to have children when chemotherapy and radiation treatments rob them of their fertili...cs in Istanbul, Turkey. Cancer treatments such as chemotherapy and radiation therapy can cause damage to a woman's reproductive system and leave her unable to have...

Chromosome Deletion Predicts Aggressive Neuroblastoma

...they should recommend a more aggressive regimen of chemotherapy to fight the cancer. Edward F. Attiyeh, M.D., a pediatric oncology fellow at The Children's Hospital of Philadelphia, reported on a study of 915 patients in a presentation today at the American Society of Clinical Oncology annual meeting in Orlando,...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...e new targeted therapy Tarceva and the widely used chemotherapy drug Taxol are effectively killing tumor cells. Th...not decreased as in the Tarceva finding - then the chemotherapy drug Taxol appears to effectively kill breast cancer cells. Taxol, used to treat a wide spectrum of...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...bevacizumab (Avastin? in combination with standard chemotherapy had a longer time period before their cancer progressed than patients who received the same chemotherapy without bevacizumab. The clinical trial was sponsored by the National Cancer Institute (NCI), part ...

Disease progression model of pancreatic cancer developed by Penn researchers

...al of cancers, with a one-year survival rate after chemotherapy of only 17 to 28 percent of patients, according to the National Cancer Institute. Sunil R. Hingorani, MD, PhD, and David A. Tuveson, MD, PhD, both in the Departments of Medicine and Cancer Biology, and colleagues, engineered mice to express two muta...

New polysaccharide may help combat multidrug resistance in cancer

...uronan antagonists can be used in conjunction with chemotherapy such that much lower and less toxic doses of chemotherapeutic agents can be used." ...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

...ays of intervening and preventing the evolution of chemotherapy resistance in these cancer cells. Last year Romesberg was awarded a Department of Defense Breast Cancer Research Program Idea Award of $563,100 to identify the genes in Saccharomyces cerevisiae yeast and human cells that induce mutations that can tra...

'Smart drug' targets deadly brain cancer

...sually treated with surgery, radiation therapy and chemotherapy -- and median survival is 12 to 16 months. For patients in whom the disease recurs, the prognosis is indeed dismal: there are no good treatment options. The Next Step Mayo Clinic researchers are continuing to investigate the implications of their f...

NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma

.... This immunotherapy consisted of a combination of chemotherapy and reintroduction of their own (autologous) activ... Next, patients were treated for two days with the chemotherapy agent cyclophosphamide followed by five days of fludarabine. The chemotherapy drugs were used to red...

UCLA cancer researchers shake loose hidden biomarker

Using a common chemotherapy agent, researchers at UCLA's Jonsson Cancer Center...karan and his team employed a commonly used cancer chemotherapy agent, which destroys the microtubules. "These patients are getting chemotherapy anyway, and once w...

MIT engineers an anti-cancer smart bomb

...earch team. "The fundamental challenges in cancer chemotherapy are its toxicity to healthy cells and drug resista...ies. The next obvious solution would be combining chemotherapy and anti-angiogenesis--dropping the bombs while cutting the supply lines. But combination therapy co...

Stem cells in bone marrow replenish mouse ovaries

...ovaries of normal mice and mice that had undergone chemotherapy appeared nearly identical, Tilly and colleagues discovered. Expression of a germ cell marker in bone marrow fluctuated regularly with the female mouse's estrous cycle, much like the cyclical rise and fall of certain hormones. Further results suggest...

Major breakthrough in the treatment of cancers and infectious diseases

...hese medications could be used in combination with chemotherapy and radiotherapy to improve the effectiveness of anti-cancer treatments. Teams around the world have been trying without success for many years to develop methods to increase NK cell activity. In this light, the discovery of Dr. Veillette's team open...

USC researchers determine mechanism of action of chemotherapy drug

The chemotherapy drug motexafin gadolinium (brand name: Xcytrin, manufactured by Pharmacyclics, Inc.) works to thwart cancer cells by disrupting key enzymes involved in cellular metabolism, according to a team of researchers led by Joseph Hacia, Ph.D., assistant prof...

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