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Tag: "chemotherapy" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...ivering a wide range of drugs ?from painkillers to chemotherapy cocktails ?to specific areas of the body, potentially resulting in improved treatment outcomes and perhaps saving lives, the researchers say. The molecule also shows promise for a wide range of other applications, including the removal of environmen...

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

... to the lymph nodes and chest wall) to a course of chemotherapy after radical mastectomy in premenopausal women wi... Center in Montreal, and colleagues found that the chemotherapy and radiation regimen, compared with chemotherapy alone, was associated with improvement in all end ...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

... to the lymph nodes and chest wall) to a course of chemotherapy after radical mastectomy in premenopausal women wi... Center in Montreal, and colleagues found that the chemotherapy and radiation regimen, compared with chemotherapy alone, was associated with improvement in all end ...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...essive course. In these cases, patients do require chemotherapy and have a lifespan of only about six to eight years after diagnosis despite treatment. Scientists, including Drs. Chiorazzi, Rai and others at North Shore-LIJ, as well as other research groups in Bethesda, MD, San Diego, CA, and Barcelona, Spain, h...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...onal techniques if the tumor was responding to the chemotherapy or radiation therapy. This has potential to spare patients from weeks of a grueling treatment regimen that's not working and gives doctors the opportunity to switch patients early on to a therapy that may be more effective. Results of the study appe...

Gene variations explain drug dose required to control seizures

...s' genetic makeup might also influence the dose of chemotherapy needed to successfully fight a tumor, while minimizing often intolerable side effects. ...

Purdue proves concept of using nano-materials for drug discovery

...ponsible for cancer's ability to resist anti-tumor chemotherapy drugs. These proteins act as tiny pumps that quickly remove chemotherapy drugs from tumor cells, making the treatment less effective. Cancer cells exposed to chemotherapy dr...

Taking Aim With Nanoparticle PEBBLEs

...cells when triggered by exposure to light. Unlike chemotherapy drugs that attack tumors by invading cancer cells ...he cell, PEBBLEs avoid a problem that thwarts many chemotherapy drugs. "The really bad cancer cells get immune to chemotherapy drugs ?they pump the drugs back out,...

Researchers add new tool to tumor-treatment arsenal

..."The use of DNA-damaging agents has revolutionized chemotherapy against a wide variety of cancers," says Dr. Thomas. "However, a narrow therapeutic window, combined with possible severe side effects, has greatly limited their broader use." These factors, says Dr. Thomas, have probably contributed to recent repor...

Potential Cure for Lymphoma in HIV patients

...ent-relatedcomplications. The ability of high dose chemotherapy as demonstrated inthis pilot study to effectively ...ents had undergone previousstandard-dose frontline chemotherapy for their lymphoma, but themajority either failed to achieve a complete remission or had relapsedaft...

Breast Cancer May Be 'Uniquely Sensitive' To Inhibitors Of PI3K Pathway

... drugs in combinationwith other treatments such as chemotherapy may significantly advancebreast cancer care,?he says....

Genetic Variation Visualization - From EMBL

... drugs in combinationwith other treatments such as chemotherapy may significantly advancebreast cancer care,?he says....

New Mixing Method for Microchip-Sized Labs

... drugs in combinationwith other treatments such as chemotherapy may significantly advancebreast cancer care,?he says....

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

...a that takes a fraction of the time of traditional chemotherapy with fewer side effects caused tumors to shrink in...hat's been used for follicular lymphoma, including chemotherapy regimens that take months to complete. It's very well-tolerated by patients and we saw complete remi...

Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin

...irectly to a tumor, enabling us to actually see if chemotherapy is really going to its intended target." This work takes advantage of years of effort in the Therien laboratory focused on the design of highly fluorescent compounds. Polymersomes, which were developed by Penn professors Daniel A. Hammer and Dennis ...

Effective Cancer Treatments Follow The Clock

...ay provide a rationale for adjusting the timing of chemotherapy to make it less toxic. “There is one more very important clinical application of these findings,?Antoch said, “as they provide a rationale for developing drugs that can enhance the therapeutic index through the modulation of the circadian clock. We h...

Potential treatments for neurofibromatosis

...challenging to treat surgically, and radiation and chemotherapy don't help," said Dr. Clapp. ...

Pulsating ultrasound enhances gene therapy for tumors

...ast permeable cancers and does not respond well to chemotherapy or radiation. However, these types of tumors have responded to certain types of therapeutic genes. "This procedure is hypothetically generic for enhancing delivery to all tissues," Dr. Frenkel said. "Previous studies by Dr. Li have shown that pulsed...

Nanoparticles offer new hope for detection and treatment

...ether a tumor was still growing after radiation or chemotherapy treatments. Although this study focused on melanoma tumors, the researchers believe the technology should work for most solid tumors, because all tumors must recruit new blood vessels to obtain nutrients as they grow. Nevertheless, melanoma has uni...

Buying Time Through Hibernation on Demand

...ke them a less-vulnerable target for radiation and chemotherapy and thus spare normal tissue during high-dose cancer therapy. "Right now in most forms of cancer treatment we're killing off the normal cells long before we're killing off the tumor cells. By inducing metabolic hibernation in healthy tissue we'd at ...

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