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Tag: "chemists" at biology news

A slight difference and significant similarities

...lture and Food, were tested. A team of biologists, chemists and computer scientists from Potsdam and Aberystwyth in Wales took part in the evaluation. ...

Structures of marine toxins provide insight into their effectiveness as cancer drugs

...cal meaning to this area." He adds that synthetic chemists hope that actin-based drugs might one day rival the success of Taxol, a powerful drug derived from a natural product that keeps breast-cancer cells from dividing. "Actin-based drugs have not yet been used as successful drugs as have those that targe...

NYU chemists use computer simulation to enhance understanding of DNA transcription

New York University chemists have employed a computer simulation whose results ...ns unclear. The research team, which included NYU chemists Tamar Schlick, Jian Sun (now at the Cornell Medical School), and Qing Zhang, analyzed a 12-nucleosom...

A radical solution for environmental pollution

...unusual---not the standard chemical reactions that chemists usually think about," said Marsh. "It turns out that the solution to metabolizing these very inert compounds is to harness the reactive chemistry of free radicals. To a chemist it's an elegant solution to a difficult problem---even if we still don't ...

Drugs from the deep blue

... be made more efficiently. "It's excited a lot of chemists and cancer biologists," Molinski said. Molinski's group has also gone fishing for drugs that modulate calcium channels within cells, in collaboration with Isaac Pessah, professor and director of the Center for Children's Environmental Health at the ...

UW-Madison scientists zero in on drugs' sweet spots

...l agents. Critically, the method allows medicinal chemists to investigate the biological effects of the many forms of sugars or carbohydrates found in nature. "There are many different variations of sugars -- they're all over the place in nature -- and they are very important. This method allows us to rapidl...

Many cats unaffected by catnip, C&EN reports

... multidisciplinary membership of more than 158,000 chemists and chemical engineers. It publishes numerous scientific journals and databases, convenes major research conferences and provides educational, science policy and career programs in chemistry. Its main offices are in Washington, D.C., and Columbus, Oh...

Biotechnology's newest chemical tool

...titute of Biotechnology in Vilnius, Lithuania, and chemists at the Institute of Organic Chemistry in Aachen, G... carbon atom attached to three hydrogens, known to chemists as a methyl group -- to specific bases within a DNA sequence, methyltransferases can effectively shu...

Katrina floodwaters not as toxic to humans as previously thought, study says

... multidisciplinary membership of more than 158,000 chemists and chemical engineers. It publishes numerous scientific journals and databases, convenes major research conferences and provides educational, science policy and career programs in chemistry. Its main offices are in Washington, D.C., and Columbus, Oh...

New technique helps researchers determine amino-acid charge

...sue of Nature, are expected to be welcome news for chemists and biophysicists, both experimentalists and theoreticians, because they have previously relied on theoretical estimations to predict protonation states -- whether an amino acid is charged or not. Appropriate experimental benchmarks also had been lac...

'Computer-chemistry' yields new insight into a puzzle of cell division

...ided by Duke computer scientists and computational chemists have identified the likely way two key enzymes dock in an intricate three-dimensional puzzle-fit to regulate cell division. Solving the docking puzzle could lead to anticancer drugs to block the runaway cell division behind some cancers, said the res...

MIT chemist discovers secret behind nature's medicines

...eate self-medications, such as anti-fungal agents, chemists have discovered the simple secret. Scientists alr... and bind to the iron, without the grand theatrics chemists had anticipated. After the iron and the chloride bind, the protein closes down around the active sit...

New University of Toronto research a 'pore' excuse for engineering

A new study by chemists and engineers at the University of Toronto describes a nanoscale material they've created that could help satisfy society's never-ending hunger for smaller digital devices and cellphones, and could even lead to new methods for delivering medications ...

AIDS drug from sunflowers

...roduction of DCQA a distinct possibility. Even now chemists can 'copy' the substance, albeit only with great difficulty. 'The tricky bit is transferring the caffeoyl groups to the quinic acid,' Ralf Theisen says. 'The plants probably only have one enzyme, which acts as a catalyst for this transfer. If we can ...

Creation of antibiotic in test tube holds promise for better antibiotics

... nisin efficiently," van der Donk said. "Synthetic chemists in the past needed 67 steps to make it, while nature uses just two enzymes. One of these is the cyclase whose activity we have demonstrated in this paper." The thioether rings vary in size from four to seven amino acids and provide sturdy protease-r...

New 'self-exploding' microcapsules could take sting out of drug delivery

Belgian chemists have developed "self-exploding" microcapsules that could one day precisely release drugs and vaccines inside the human body weeks or even months after injection. The study, by researchers at Ghent University and the Universit? Catholique de Louvain, ...

New lab technique churns out fungus' potential cancer fighter

...rry out tests. To bring about a new drug, organic chemists must produce a new chemical in enough quantity to test it under many different circumstances to tease out its modus operandi. Until now, no method existed to generate rasfonin, aside from growing more fungus--a time-consuming and terribly inefficient...

New lab technique churns out fungus' potential cancer fighter

...rry out tests. To bring about a new drug, organic chemists must produce a new chemical in enough quantity to test it under many different circumstances to tease out its modus operandi. Until now, no method existed to generate rasfonin, aside from growing more fungus--a time-consuming and terribly inefficient...

'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage

... it--has remained less clear. Now, computational chemists at the University of Georgia have discovered for t...Steven Wheeler. Call it a "pinball proton." While chemists have shown other causes of DNA damage, the report in PNAS is the first to report how protons, knocke...

Small molecule interactions were central to the origin of life

... supported by "prebiotic" syntheses carried out by chemists using modern apparatus and purified reagents, are highly unlikely. The creation of a molecule that can self-replicate requires the combination of diverse chemicals in a long sequence of reactions in a specific order, interspersed by complicated separ...

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