Sugar helps control cell division
...lawson, Ph.D., a postdoctoral fellow in biological chemistry in Johns Hopkins' Institute for Basic Biomedical Sciences. "In contrast, our experiments show that by increasing or decreasing the amount of sugar attached to proteins, the cell cycle is disrupted and isn't salvageable unless O-GlcNAc levels are fixe......his information will help Arun Ghosh, professor of chemistry at UIC, build protease inhibitors, like the prototype he assembled earlier, through what is called structure-based drug design. He will create computer images of each enzyme coupled with compounds anticipated to obstruct the pockets, revealing whethe...Rensselaer researchers develop approach that predicts protein separation behavior
...n a computer," said Curt M. Breneman, professor of chemistry and chemical biology at Rensselaer. "The ability to predict the separation behavior of a particular protein directly from its structure has considerable implications for biotechnology processes," said Steven Cramer, professor of chemical and biologi...Stem cell training program to make its Stanford debut
...n you make that so-called hybrid molecule, all the chemistry associated with the original compound changes,?said Noel. He explained that the addition of a prenyl group, also known as prenylation, produces a relatively large change in the chemical’s biological properties. “The molecule becomes a little bit more...Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure
...n you make that so-called hybrid molecule, all the chemistry associated with the original compound changes,?said Noel. He explained that the addition of a prenyl group, also known as prenylation, produces a relatively large change in the chemical’s biological properties. “The molecule becomes a little bit more...Thinking the pain away? Study shows the brain's painkillers may cause 'placebo effect'
...ew study is the first to pinpoint a specific brain chemistry mechanism for a pain-related placebo effect. It may help explain why so many people say they get relief from therapies and remedies with no actual physical benefit. And, it may lead to better use of cognitive, or psychological, therapy for people wit...Harmless virus may hold key to more effective HIV drug discovery
...biologists," said Weiss, an assistant professor of chemistry and molecular biology and biochemistry. "By recruiting a harmless virus, we're learning how HIV will respond to new classes of anti-viral drugs before these compounds are tested in the clinic, which is currently an expensive and time-consuming proces...Major advance made on DNA structure
...her early and profoundly important work in protein chemistry was done by Linus Pauling, an OSU alumnus and himself the recipient of two Nobel Prizes. However, Watson and Crick actually identified only one structure of DNA, called B-DNA, when in fact there are many others ?one of which was discovered and anoth...Breakthrough: Scientists create world's tiniest organic particles
...e, William R. Kenan Jr. Distinguished professor of chemistry and chemical engineering at UNC and N.C. State Uni...American Chemical Society. Other authors -- all in chemistry at UNC -- are Drs. Jason P. Rolland and Ginger M. Denison, recent Ph.D. recipients; Drs. Benjamin W....Bad aftertaste? New sensory on/off switch may 'cure' bane of artificial sweetener search
...ost doctoral associate in chemistry; Virginia Tech chemistry undergraduate students Jerita Dubash, of Ashburn, Va., and Matthew Jeletic, of Centreville, Va., graduate students David F. Zigler, of Sterling, Ill., Julie Heinecke, of Powhatan, Va., and Ran Miao, of Zhangzhou City, China, and biology professor Bre...Virginia Tech group adds tools to DNA-targeted anti-cancer drugs
...ost doctoral associate in chemistry; Virginia Tech chemistry undergraduate students Jerita Dubash, of Ashburn, Va., and Matthew Jeletic, of Centreville, Va., graduate students David F. Zigler, of Sterling, Ill., Julie Heinecke, of Powhatan, Va., and Ran Miao, of Zhangzhou City, China, and biology professor Bre...By creating molecular bridge, scientists change function of a protein
...iology at Illinois. He also is an affiliate in the chemistry and bioengineering departments. ...MIT engineers an anti-cancer smart bomb
...loon with chemotherapy agents. A "stealth" surface chemistry allows the nanocells to evade the immune system, while their size (200 nanometers) makes them preferentially taken into the tumor. They are small enough to pass through tumor vessels, but too large for the pores of normal vessels. Once the nanocell ...Life detection instrument passes key test on road to Mars
...bsolute proof of life," said Mathies, professor of chemistry at UC Berkeley and Skelley's research advisor. "We've shown on Earth, in the most Mars-like environment available, that this instrument is a thousand times better at detecting biomarkers than any instrument put on Mars before." The instrument has be...Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines
... chemistry, and Sarah Chobot and Andrew Wojtovich, chemistry undergraduates in the College of Arts and Sciences. The research was supported by funds from the Department of Energy, the National Institutes of Health, the National Heart, Lung, and Blood Institute’s Proteomics Initiative, the Whitaker Foundation,...Atmosphere may cleanse itself better than previously thought
...ofessor of both earth and atmospheric sciences and chemistry in Purdue’s College of Science. "We now have a bet...cause the models are underestimating the amount of chemistry that’s happening," said Sinha, who is an associate professor of chemistry and biochemistry. "It coul...Innovative coating could give medical implants a longer life
...idely studied antifouling polymer. "We had a rich chemistry available to us when designing this polymer," said Messersmith. "The chemical characteristics of the antifouling component are similar to polyethylene glycol but it lasts longer because it is a peptoid and enzyme resistant. Plus, the structure of the...Chemists synthesize molecule that helps body battle cancers, malaria
...ts performance," said David Y. Gin, a professor of chemistry at Illinois. Gin and his collaborators describe their work in a paper that has been accepted for publication in the Journal of the American Chemical Society, and posted on its Web site. An extremely powerful adjuvant, QS-21A enhances the potency of ...Purdue researchers use enzyme to clip 'DNA wires'
... assistant professor of biomedical engineering and chemistry at Purdue. DNA, or deoxyribonucleic acid, has an overall negative charge, so it might be used in a process called self-assembly to create electronic devices. When placed in a solution with magnetic particles that have a positive charge, the particle......ongly to rocks," said Li, who is an expert in wood chemistry and adhesives in the OSU Department of Wood Scienc...rce." Li decided to look much more closely at the chemistry of the mussels' byssus, which are small threads that attach them to rocks and other surfaces. The by...