Cellular scale drug delivery from the inside out
...o carry drugs inside living cells, Ames Laboratory chemist Victor Lin is studying different methods to control whether or not the particle delivers its pharmaceutical payload. "First, the nanospheres are only about 200 nanometers in diameter, roughly the size of a virus, so they won't trigger an immune res...Pair of studies offer new clues to combat antibiotic resistance
... co-author Timothy C. Meredith, Ph.D., a medicinal chemist who conducted the research as a doctoral student at the University of Michigan with Ron Woodard, Ph.D., a professor of medicinal chemistry at the university. Meredith is currently a researcher at Harvard Medical School in Boston. Gram-negative bacte...Sea coral's trick helps scientists tag proteins
...abeling in 1994, said Marc Zimmer, a computational chemist at Connecticut College and author of Glowing Genes: A Revolution in Biotechnology (2005). Since then, HHMI investigator Roger Tsien has developed a veritable rainbow of refined high-performance GFP mutants. A major breakthrough in fluorescent prote...Creation of antibiotic in test tube holds promise for better antibiotics
...anying Perspectives article in Science, written by chemist David W. Christianson of the University of Pennsylvania, suggests that nisin's five thioether rings may turn out to be golden "in the never-ending search for blockbuster antibiotics." ...Scientists find Antarctic ozone hole to recover later than expected
...n a weekly basis," said Steven Montzka, a research chemist in the Global Monitoring Division at NOAA's Earth Systems Research Laboratory in Boulder, and co-author of the paper. "We make calculations with that information to determine how gases containing chlorine and bromine that have life spans in the atmos...Rice scientists make first nanoscale pH meter
...pH units. The term "pH" was coined by the Danish chemist Søren Sørensen in 1909 as a convenient way of expressing a solution's acidity. pH ranges from one ?the most acidic ?to 14 ?the most alkaline. ...Mosquito spray increases toxicity of pyrethroids in creek, study finds
...esearcher in integrative biology; Abdou Mekebri, a chemist at the California Department of Fish and Game; and R. Scott Ogle, a toxicologist at Pacific EcoRisk. Pyrethroids have risen to dominance as organophosphate pesticides, including diazinon and chlorpyrifos, are phased out due to concerns over their e...Nanowire arrays can detect signals along individual neurons
...and dendrites of live mammalian neurons. Harvard chemist Charles M. Lieber and colleagues report on this marriage of nanowires and neurons this week in the journal Science. "We describe the first artificial synapses between nanoelectronic devices and individual mammalian neurons, and also the first linki...Exxon Valdez oil found in tidal feeding grounds of ducks, sea otters
...Science & Technology . The study, by research chemist Jeffrey Short and colleagues at the National Marine Fisheries Service in Juneau, Alaska, is also scheduled to appear in the June 15 print issue of the journal. "This study shows that it is very plausible that exposure to Exxon Valdez oil is having ...Triple threat polymer captures and releases
A chemist at Washington University in St. Louis has developed a remarkable nanostructured material that can repel pests , sweeten the air, and some day might even be used as a timed drug delivery system –as a nasal spray, for instance. Karen L. Wooley, Ph.D....With record resolution and sensitivity, tool images how life organizes in a cell membrane
...ey're organized, according to Stanford biophysical chemist Steven Boxer. With colleagues at Stanford, the Uni...tells you which component is which. I'll put on my chemist hat now. When a chemist says, 'I know what's there,' he or she means, 'I know chemically what's ther...An artificial cornea is in sight, thanks to biomimetic hydrogels
...esion to the material. Michael Carrasco, a peptide chemist at Santa Clara University, consulted about surface modifications for cellular adhesion. The researchers are now testing the material for biocompatibility in animal models. Animals have tolerated artificial corneas with no problems in trials as long...BC catalyst discovery promises faster, cheaper drug production
...ican health care consumer," said John M. Schwab, a chemist at the National Institute of General Medical Science,which supported the work. ...Edible coatings will be the packaging of the future
...sweeping and aluminium foil. The Pamplona research chemist holds that WPI films are the packaging of the future, although the commercial exploitation of the application is yet to materialize. There are many possibilities ?on the one hand, they will prolong the useful life of foodstuffs in a healthy way and, ...Bacteria in small sea life yield new way to make potential cancer drugs
Researchers led by a University of Utah medicinal chemist have developed a novel method to make drugs for cancer and other diseases from bacteria found in sponges and other small ocean creatures. In a study published Sunday, Nov. 5, in Nature Chemical Biology online, researchers examined symbiotic bacteri...Dopamine used to prompt nerve tissue to regrow
When Yadong Wang, a chemist by training, first ventured into nerve regeneration two years ago, he didn't know that his peers would have considered him crazy. His idea was simple: Because neural circuits use electrical signals often conducted by neurotransmitters (chemical mess...Faster, low cost sequencing technologies needed to drive era of personalized medicine
...ncer, heart disease, diabetes and obesity. ASU chemist Peiming Zhang and his collaborator Jian Gu have been awarded a $897,000 grant under this program for an ambitious DNA sequencing project that combines physics, chemistry and nanotechnology with engineering. The researchers have been charged with the...A sweet step toward new cancer therapies
...que developed by University of Michigan analytical chemist Kristina Hakansson sets the stage for new cancer diagnosis and treatment options. A growing body of evidence points to assemblies of sugars called glycans attached to proteins on cancer cell surfaces as accomplices in the growth and spread of tumors...Nanotechnology meets biology and DNA finds its groove
... C. Schwartz, a UW-Madison genomics researcher and chemist and the senior author of the PNAS paper. "And in order to read the molecule, you have to present the molecule." To attack the problem, Schwartz and his colleagues turned to nanotechnology, the branch of engineering that deals with the design and m...A chemist at Washington University in St. Louis is making molecules the new-fashioned way ?selectively harnessing thousands of minuscule electrodes on a tiny computer chip that do chemical reactions and yield molecules that bind to receptor sites. Kevin Moelle...