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Tag: "chemically" at biology news

New miniaturised chip dramatically reduces time taken for DNA analysis

...hemical sensors. These can identify a substance by chemically interacting with it and converting this interaction into an electrical current that they measure. To detect DNA, the new miniaturised electrochemical genosensors have a probe containing DNA fragments that complement the DNA they aim to detect. For e...

Random gene expression may drive HIV into hiding

... into the host genome. At this point, Tat must be chemically modified before it can encourage transcription of more HIV, and random thermal fluctuations in the cell can influence if and when these chemical modifications take place. Because of Tat's positive-feedback loop, "these fluctuations can be amplified ...

New tool reveals secrets of migrating cells

...migrations have been inferred from observations of chemically fixed tissue at different stages of development. "Two-photon imaging is going to change literally forever the way that we do biological science," said Witt, a developmental immunologist. "In the past, we'd take organs out, smush them up and basicall...

Harmless virus may hold key to more effective HIV drug discovery

...on of Nef mutational variants. The results suggest chemically simpler, more flexible compounds could better accommodate viral mutations. The research is part of a UCI program aimed at expanding the anti-HIV drug arsenal. The program includes National Academy of Sciences member Larry Overman in the Department ...

Structures of marine toxins provide insight into their effectiveness as cancer drugs

...ered to be as effective as possible. "In order to chemically synthesize a better drug, it is a good idea to know how the natural compound works," he says. "Scientists who study natural products take their cues from what nature has already done. We're adding deep biochemical meaning to this area." He adds th...

Discovery of T-cell 'traffic control' boosts new drug promise

...periment, Goetzl's and Rosen's labs showed that by chemically displacing S1P, its natural braking effect is released, stimulating T cell traffic into lymph nodes. Because this also blocks S1P's chemotactic influence, migration of T cells out of the lymph nodes is greatly reduced. T cells are essentially sequest...

Molecular miners find pain relief drugs from the sea

...solely from the DNA sequence. The peptide was then chemically synthesised in large quantities suitable for biological testing. This same approach is now being used by Metabolic Pharmaceuticals to synthesise gram amounts of ACV1 needed for the planned human clinical trials for diabetic neuropathy. "With an incr...

UF researchers kill resistant bugs one bandage at a time

...ch year. This microbicidal coating - which can be chemically bonded to gauze bandages, socks and even hospital ... A patent is pending on the researchers' method of chemically bonding the substance to fabrics and other materials. This method allows the substance to be efficie...

Hunt for human genes involved in cell division under way

...se a method called 'RNA interference (RNAi)' where chemically synthesized RNA molecules are used to target and s...presents the first use of a genome-wide library of chemically synthesized siRNAs in academic research and these partners have provided us with the tools to carry ...

Breakthrough in micro-device fabrication combines biology and synthetic chemistry

...rating that biologically derived structures can be chemically modified without changing the starting shapes or fine features, we have opened the door for new research and development in the processing and application of many devices that would otherwise be very difficult or expensive to produce." ...

Researchers find molecule that inhibits regrowth of spinal nerve cells

...in the damaged area, but components of myelin also chemically prevent nerve cells from regrowing there as well. ... past 10 years to identify elements in myelin that chemically inhibit the regeneration of nerve cells, Dr. Parada said. Three individual components ?the molecules...

Scientists discover new way to look at how molecules twist and turn on water

...roach that has broad implications for a variety of chemically and biologically important applications." "With the head groups of these molecules happy to be surrounded by water molecules at the water surface and their tails preferring to stick up out of the water, extending into the air or an adjacent oily lay...

Method slashes quantum dot costs by 80 percent

... cadmium and selenium compounds are injected. They chemically decompose and recombine as pure CdSe nanoparticles. Once these nanocrystals form, scientists can adjust their optical properties by growing them to precisely the size they want by adjusting the cooking time. The solvent originally used for this proc...

The right drug at the right time

... cadmium and selenium compounds are injected. They chemically decompose and recombine as pure CdSe nanoparticles. Once these nanocrystals form, scientists can adjust their optical properties by growing them to precisely the size they want by adjusting the cooking time. The solvent originally used for this proc...

Researchers learn how blood vessel cells cope with their pressure-packed job

... that when an intracellular protein called Rho was chemically inhibited, stress fibers grew in the "wrong" direction; they grew parallel rather than perpendicular to the direction of cell stretching. Without Rho, the cells lost their ability to orient stress fibers properly. "Rho is a very important molecule," ...

New factor implicated in allergy and asthma attacks

...asthma attack. This factor is the damage caused by chemically hyperactive molecules known as "reactive oxygen species," which are spawned by interactions between a single pollen-carried enzyme and the cells that line airways. And, the researchers say, if an effective way can be found to reduce that damage--call...

War on terror meets war on cancer

...membranes and pores that the water inside cells is chemically identical to the water outside cells. Scientists from the University of Utah in Salt Lake City and Pacific Northwest National Laboratory in Richland, Wash., published the study the week of Monday Nov. 21 in the online edition of the journal Proceed...

NIAID researchers show how promising TB drug works

...newsreleases/2005/tb_pa_824.htm .) PA-824 must be chemically activated in the bacterium before it exerts its anti-tubercular effect, notes Dr. Barry. Earlier research had sketched out the first few steps in this process, but Dr. Barry and his colleagues wanted to pinpoint the precise protein that binds PA-824 ...

Genes involved in biofilms

... strategy arose during the development of a medium chemically defined in order to study how environmental signals affect the process of formation of the biofilm. Unexpectedly, most of the clinical strains of Staphylococcus aureus were unable to form biofilm in the synthetic medium, which suggested to us that ...

UCR environmental scientists propose chemical solution to cleaning California's Salton Sea

...d settling. The polymer acts as a coagulant aid by chemically bridging reactive groups and increasing floc size. ...

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