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Tag: "checkpoint" at biology news

New binding target for oncogenic viral protein

...arge T antigen. This protein corrupts the cellular checkpoint mechanisms that guard cell division and the transcription, replication and repair of DNA. T antigen also inactivates some of the most important proteins that protect cells against malignant transformation, including tumor suppressor proteins p53 and ...

Novel connection found between biological clock and cancer

...t result of action by an enzyme, called in mammals checkpoint kinase-2 (CHK2), whose normal role is exclusively ... homolog, the Neurospora version, of the mammalian checkpoint kinase. Moreover, the clock regulates expression of the period-4 gene. This closes a loop connectin...

MIT sheds light on how tumor cells form

... MIT researchers have discovered is a reason these checkpoint proteins may be unable to sense the defective cell...called microtubules. If they attach correctly, the checkpoint proteins give them the go-ahead to divide. If they don't, the checkpoint proteins are supposed to st...

Worm links cancer risk to ageing

...y that is. Professor Lithgow said: "If we look at checkpoint proteins as a gear, we have known for a long time ...r Lithgow now works, involved genetically removing checkpoint proteins in the microscopic worm C. elegans. By doing so, the researchers caused a 15-30% increase i...

Cancer stem cells linked to radiation resistance

...a specific cellular process called the "DNA damage checkpoint response" appears to enable cancer stem cells to s...oth study models, the team examined the DNA damage checkpoint response both before and after use of ionizing radiation treatments by testing for activation of the...

ATR checkpoint-activating DNA structure

... precisely define and manipulate the nature of the checkpoint activating structure in an experimental system will enable us to control, quantitative and probe checkpoint signaling responses in unprecedented ways." Using Xenopus egg extracts as a cell-free system, the...

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(Date:7/10/2014)... partners predict that western Lake Erie will have a ... the 2014 bloom season in late summer. However, the ... year,s intense bloom, and considerably less than the record-setting ... lake,s western basin and are classified by an estimate ... , Harmful algal blooms (HABs) were common in ...
(Date:7/10/2014)... Clarksburg, MDBrightFocus Foundation, a nonprofit organization funding cutting-edge, ... diseases of glaucoma and macular degeneration, today announced ... to 55 scientists in 19 U.S. states, the ... http://www.brightfocus.org/Grants2014 . , With these latest ... million in research funding in 2014. , The ...
(Date:7/10/2014)... collected by the Moderate Resolution Imaging Spectroradiometer (MODIS) aboard ... spot, which appears as a red mark, is an ... recognized temperatures higher than background. When accompanied by plumes ... are diagnostic for fire. , This area of ... from the fires, although the smoke released by any ...
Breaking Biology News(10 mins):NOAA, partners predict significant harmful algal bloom in western Lake Erie this summer 2NOAA, partners predict significant harmful algal bloom in western Lake Erie this summer 3BrightFocus Foundation announces 55 new grantees in Alzheimer's and vision research 2BrightFocus Foundation announces 55 new grantees in Alzheimer's and vision research 3
(Date:7/10/2014)... as tempting as full-fat equivalents could be heading ... how proteins can replace fats without affecting foodstuffs, ... Engineering and Physical Sciences Research Council (EPSRC), a ... Edinburgh has produced modified proteins that easily break ... behaviour of fats during food manufacture. The proteins ...
(Date:7/9/2014)... 2014 -- The World Health Organization recommends that youth ... to vigorous physical activity (MVPA) each day. Studies ... during school hours. Therefore, it stands to reason ... MVPA. In a new study scheduled for publication ... that time spent outdoors after school was positively associated ...
(Date:7/9/2014)... Perelman School of Medicine at the University of Pennsylvania ... received an $8 million grant from the National Cancer ... therapy (PDT) in patients with malignant pleural mesothelioma, a ... itself in the lining of the lungs and is ... will fund a clinical trial and additional studies looking ...
(Date:7/9/2014)... Studying the most common type of lung cancer, researchers ... a role in forming tumors. The new knowledge may ... these genetic changes already are available or are in ... , investigators from The Cancer Genome Atlas (TCGA), including ... Louis, Harvard Medical School and other institutions, studied tumors ...
(Date:7/9/2014)... used in policing injection drug users in Russia ... , A study, conducted by researchers from ... in collaboration with St. Petersburg Pavlov State University, ... on the health outcomes of a cohort of ... , Those who were arrested by police were ...
Breaking Medicine News(10 mins):Health News:Great tasting low-fat cheeses and cakes could soon be on the menu 2Health News:Go play outside! Outdoor time promotes physical activity in youth 2Health News:Penn mesothelioma program receives $8 million NCI grant 2Health News:Lung cancer study hints at new treatments 2Health News:BU researchers relate arrests with HIV risk environment 2
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