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Tag: "charge" at biology news

Turn-ons and turn-offs for neurons

...in the brain. Indeed, the epigenetic mechanisms in charge of switching genes “on” or “off” play an essential role when our brain learns and stores information, and when our brain reacts to injury and disease. ...

New designer lipid-like peptide with lipid nanostructures for drug delivery systems

...crystalline nanostructures. Moreover, the surface charge density of lipidic nanostructures can be varied in a simple manner. Dr. Anan Yaghmur, first author of the study, comments on the study, “the addition of small amounts of designer lipid-like peptides is sufficient to form systems with excellent po...

Fascinating spider silk

...otonated, which gives them a negative charge. This charge weakens the interactions between the hydrophobic, lipophilic regions of the proteins, which are necessary for oligomerization. "Our insights form a foundation for the establishment of an effective spinning process for the production genetically en...

Rapid, Low-Cost DNA Testing

...their opposites. An anion with a negative electric charge will attract positive charges, a cation with a positive charge will attract negative charges. Single-stranded DNA adsorbs on negatively charged citrate ions on the...

Gene that makes people 'early to bed and early to rise' demystified

...cid change associated with FASPS, which alters the charge of the residue, alters the ability of PER2 to regulate its own transcription. PER2 presumably manages such regulation through interaction with other proteins since it doesn't bind DNA itself, they said. The findings led the researchers to suggest ...

Failure to meet United Nations sanitation target could affect millions of the world's poorest

...n many countries there is simply no institution in charge of developing and enforcing sanitation policies. "But there's also a lack of leadership in stepping out and saying, this is a national crisis, it's a matter of dignity, and I'm going to change it," she said. "This is not surprising-championing excret...

Chemical switch triggers critical cell activities

...s simple switch could control comparable relays in charge of several different biochemical activities that keep cells alive and functioning normally." Schulman, a Howard Hughes Medical Institute (HHMI) investigator, is senior author of the Nature report. Scientists already knew that E1 momentarily juggl...

Tears reveal some of their deepest secrets to researchers

... lipid components. This technique adds an electric charge to microscopic droplets of the oily substance, which allows the instrument to detect different components based on electrical charges and mass. Nichols points out that researchers have used other techniques, such as chromatography, to characterize...

Microfluidic chip helps solve cellular mating puzzle

.... Only one of them, called Fus3, appeared to be in charge of the courtship process, while the other was thought to be moonlighting away from its main job in another signaling pathway. "The role of the second type of MAPK was unclear," said Saurabh Paliwal, a doctoral student in Levchenko’s lab and l...

Ultrathin films deliver DNA as possible gene therapy tool

...r. Because the polymers carry a positive electric charge that is attractive to DNA, each polymer layer also "primes" the surface to accept the next layer of DNA. While electrostatic forces between the layers keep the film stable in dry, room-temperature conditions, the polymers break down easily in a wet ...

A sweet step toward new cancer therapies

...s, rather lopping off branches. By using metals as charge carriers, the researchers were able to do just that, yielding valuable structural information. In a project that continues to build on this line of work, Hakansson is collaborating with U-M Health System cancer surgeon Diane Simeone to investigate...

ASU researchers test antibacterial effects of healing clays

...y? Organic compounds or other species of any or no charge are possible. This interlayer, as the peanut butter and jelly are termed, can vary in width and composition depending on the kinds of waters and elements present when it was formed. It is this interlayer where much of the elemental variability betwee...

Report calls for improved monoclonal antibodies against solid tumors

... investigated the optimal antibody size, shape and charge to penetrate certain types of solid tumors. Researchers have also examined how antibodies, including monoclonal therapies, behave in the human body; to understand how and how often therapies should be administered. Given these advances in our kno...

Quantum dots reviewed -- Could these nanoparticles hold the cure to cancer?

...owever, this paper is available to access free of charge in its entirety at http://www.azonano.com/Details.asp?ArticleID=1726 ...

Researchers add to understanding of how brain cells communicate

...kes a tiny piece of cell membrane and measures the charge that flows through one open channel. They were able to use the remarkable precision of the patch clamp to see exactly when the magnesium ion entered and exited the ion channel. "Because of our currently limited understanding of NR1/2D receptors, dr...

Microcapsules like it hot and salty

...This depends on the composition and the electrical charge of the polymer shell: If it shrinks, it is possible to encapsulate very small molecules. With the powerful supply of energy from raising the temperature, the bonds between the polymer molecules with opposite charges are loosened and as a resu...

K-Staters design and build a low-cost remote sensing tool for environmental studies

...aphy and a remote sensing expert. Schinstock is in charge of developing the airframe and the remote control systems for the sensing tool, while Ham and Goodin will put it to work once it's flight worthy. According to the researchers, the sensing tool/unmanned aerial vehicle should be capable of "flying low...

'Sticky' mice lead to discovery of new cause of neurodegenerative disease

...The researchers found that the mutant enzyme would charge an incorrect amino acid, serine, which resembles alanine, to tRNAs meant to carry only alanine. That meant that these tRNAs, said to be mischarged, would incorporate the incorrect amino acid into proteins. Although proteins begin as long strings of a...

How plants avoid feeling the burn

...en done before for any biomolecule: to control the charge of the biomolecule while measuring its ability to hold a current. By holding a carotenoid under potential control, Fisher could control whether the biomolecule was in a neutral state or in the charged state (the oxidized state), while simultaneousl...

Researchers win money to develop breath test to detect breast cancer

...face to fill and become dense. Then, an electrical charge would be applied so that the straight particles would bend, thus ejecting the metabolites so that multiple tests could be done in the same device. You can detect the metabolites through a change in conductance or optically The idea materialized when...

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