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Tag: "characterize" at biology news

Man and mouse share genome structures

...ia. Bernstein hopes to apply the new technology to characterize chromatin structure in leukemic cells and gain insight into the molecular basis of disease. "The human genome still has many surprises lurking within it," said Lander, director of the Broad Institute and senior author on the study. "One of the most ...

W.M. Keck Foundation funds study of friendly microbes

...terial metabolism in the intestine. The goal is to characterize previously unknown chemical compounds that play important roles in regulating the properties of the microbial community and human physiology. To do so, the researchers will use a new type of mass spectrometer with an unprecedented capacity to accurat...

Growth in the sea comes down to a struggle for iron

...oard both vessels, they made these measurements to characterize how the phytoplankton responded to the iron enrichment over a 32-day period. They also ran experiments on deck to learn how available the iron was in the patch, how diatoms were growing and coming together in multi-cellular aggregations. They studied...

PANTHER Protein Classification System Database 5.0

...lied Biosystems Expression Array System to further characterize agene of interest. Additionally, the PANTHER system workspace isintegrated with the Applied Biosystems e-commerce site so users canorder corresponding Applied Biosystems TaqMan® Gene Expression and SNPGenotyping Assays for further experimentation.?Fo...

UCSD discovery may help extend life of natural pesticide

... it genetically, in making it possible to find and characterize the structure of the long sought-after Bt receptor. However, their results apply to insects as well. Michael Adang and Stephan Garczynski, coauthors and entomologists at the University of Georgia, showed that the glycolipid receptor is present in the...

Study of genomic DNA leads to new advances in cancer diagnostics

...a purpose. The authors also used flow cytometry to characterize melanomas of varying invasiveness. Further study will be required to determine the specificity and sensitivity of these methods before they are used in the clinical setting. Physicians and researchers alike know that how a cancer cell interacts with...

LUCA technologies confirms real-time methane generation

...cess occurring today. Luca is actively working to characterize Geobioreactors and the microbial consortia that populate them, as well as to understand the metabolic processes by which those consortia generate methane. The company expects to evaluate specific Geobioreactors and their potential for conversion to m...

Chemicals in tattoo inks need closer scrutiny

...fessor of chemistry at NAU ?has two main goals: to characterize the diversity of tattoo inks, and to determine if any inks pose health threats in the form of heavy metals or other potentially dangerous chemicals. Overall, the study covers 17 inks from five different manufacturers. "We chose to study five differe...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

...s RNA. Telomerase has been extremely difficult to characterize structurally because of its size and complexity, and its low level in normal cells. "This is a unique RNA structure, with distinctive features of RNA folding," said Feigon, who determined the structure with Theimer and Blois using nuclear magnetic r...

Doctors closer to using gene analysis to help trauma patients

...is multisystem organ failure. It’s a way to better characterize the nature of the immuno-inflammatory response to trauma.?/p> Dr. Ronald G. Tompkins, a surgeon and biomedical engineer at Massachusetts General Hospital, is leading the effort to develop standard operating procedures for the care of burn and tra...

Gov't Creates Gene Database of Normal Human Tissues

...rocesses." Thus it becomes strategically useful to characterize this essential backdrop. "The normal organ database provides a platform that may help scientists find new targets in the cells of previously incurable cancers. The driving force of research in our section is to translate genomic information to the cl...

Scientists identify genes responsible for 'black rot' disease in vegetables

...atories in China have collaborated on a project to characterize the causative agent of "black rot" disease, which ...sertions, and deletions. In order to functionally characterize Xcc and identify genes implicated in its pathogenicity, the researchers then screened an Xcc transpo...

Atmosphere may cleanse itself better than previously thought

... The laser technique, however, enabled the team to characterize the minute quantities of radiation absorbed by a substance called methyl hydroperoxide when it breaks up in sunlight and forms OH radicals. Methyl hydroperoxide is one of the substances that can absorb light in the lower UV spectrum, and the team the...

U. Iowa researchers improve Huntington's disease symptoms in mice

...sychiatric disturbances and cognitive decline that characterize this disease. "Many of the current approaches aimed at treating HD are indirect and target the symptoms of the disease. RNA interference gives us the first opportunity to attack the fundamental problem and reduce protein expression from the disease ...

Lipids get new comprehensive classification system

...ys: "The goals of the LIPID MAPS initiative are to characterize known lipids and identify new ones, to quantitate the temporal and spatial changes in lipids that occur with cellular metabolism, and to develop bioinformatics approaches that establish dynamic lipid networks. In order to coordinate their efforts wit...

Unique library of plant genes germinates, takes root at UNC

... far too expensive and time-consuming, however, to characterize the genomes of all of them experimentally. "Many plants are impractical to work with experimentally because they have genomes full of material that serves no known function," Vision said. "For example, the lily genome is roughly 40 times the size of...

International Team Determines Geographic Origin of Leprosy

... of the leprosy bacterium will allow clinicians to characterize at a molecular level the M. leprae strain infecting a leprosy patient, which will show whether the patient has a new infection or if the previous infection was incompletely treated and has returned. This, in turn, will aid efforts to fully treat pati...

Scientists discover that three molecules may be developed into new Alzheimer's drugs

...rons in the brain that, along with senile plaques, characterize Alzheimer's disease. The tangles are made of "tau," a protein that is also present normally in the brain. "Tau goes wrong and becomes pathological when it becomes intensely phosphorylated," said Kosik. "This means that many phosphate groups attach t...

Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels

...rons in the brain that, along with senile plaques, characterize Alzheimer's disease. The tangles are made of "tau," a protein that is also present normally in the brain. "Tau goes wrong and becomes pathological when it becomes intensely phosphorylated," said Kosik. "This means that many phosphate groups attach t...

New protein vital for immune response is found in surprise location

...nown. Researchers have been trying to identify and characterize the proteins involved in an effort to better understand the nature of viral infection and how to combat it. Dr. Chen said he and his group believe MAVS is among a group of molecules that play a role in activating other proteins - including IRF-3 and...

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