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Tag: "channels" at biology news

Study ties 'new' cell-death mechanism to developmental and degenerative brain disorders

...ve led to speculation that voltage-gated potassium channels could be involved in human neurodegenerative disease, but proof has been lacking," Pulst said. "This is the first time neurodegeneration has been directly linked to potassium channel mutations." In the Nature Genetics article, the researchers descr...

Cellular scale drug delivery from the inside out

...y possible. The spheres have thousands of parallel channels running completely through them. Through capillary...up molecules of the drug to be delivered. When the channels are filled, the ends of channels are "capped" to safely seal the drug inside. Once the caps are in p...

New technique helps researchers determine amino-acid charge

...cking. All cells have membrane proteins that form channels to allow water and/or ions to pass through. Malfunctions have been linked to such problems as hypertension, abnormal insulin secretion, abnormal heart conditions and brain seizures. As a result, these membrane proteins are often targeted by drug trea...

What can change in the brain? Electrical synapses, research shows

... ago. The function and importance of these protein channels - which allow for lightening-quick signals to pass between neurons via ionic current - is only beginning to be understood. Last year, the Connors lab published research showing that electrical synapses help set the brain's master circadian clock. ...

Sahara's edge studied from ground, air and space to improve water management

...superior in geometric resolution and the number of channels or polarisations to the capability of presently orbiting satellites - will also be used to anticipate the performance and usefulness of future satellite sensors. Aquifer and TIGER The Aquifer Project has in addition to SASS a second working area...

New understanding of regeneration gained by Forsyth scientists

...nding how cells communicate through gap junctional channels we can gain a greater understanding of how we can possibly direct this process in tissues that don't currently regenerate; this has clear applications towards induction of regeneration in biomedical settings." Dr. Levin and his team ultimately hope t...

Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace

...es sensitive to the opening and closing of calcium channels on neurons. The scientists created an imaging grid across the glomeruli and measured the ratio of fluorescence versus nonfluorescence over time. Galán then used advanced mathematical techniques to process the images and create a matrix of the extent...

Membrane research opens window to benefits for plants, humans

...conserved in them. "Plant cells close their water channels in response to drought stress in order to preserve... the structural difference between open and closed channels is telling. When open, the protein allows water to go through; when closed, its pore size is reduced...

Machinery of the 'marijuana munchies'

...he endocannabinoid effects by inhibiting pore-like channels in the neurons that regulate the flow of calcium into the neurons. Such calcium is necessary for the synthesis of endocannabinoids. In further studies of mice genetically altered to be leptin deficient, the researchers found the DSI to be more prolo...

Molecular cabal contributes to stroke damage

...n sensation, "a similar coupling between these two channels is likely to occur in these diseases as well." ...

'Nanospheres' that block pain of sensitive teeth

...ntine is made up of thousands of tiny fluid-filled channels which radiate outwards from the nerve endings at t... and physical contact can cause the fluid in these channels to move ?in or out ?triggering the nerve endings and causing sharp pain. If these channels (or 'tu...

Stem cells' electric abilities might help their safe clinical use

...ins have discovered the presence of functional ion channels in human embryonic stem cells (ESCs). These ion channels act like electrical wires and permit ESCs, versatile cells that possess the unique ability to become...

Retinal scans eyed for New Mexico show cattle

...oard. At that time, all animals entering marketing channels must be identified. Now, a final report on both NMSU animal ID technology studies is being compiled for USDA, Encinias said."In the future, we need to look at just how long the RFID tags last under New Mexico's varied and sometimes brutal climate c...

NHGRI expands effort to revolutionize sequencing technologies

...current, as it passes through a membrane with tiny channels known as nanopores. Jene A. Golovchenko, Ph.D., Harvard University, Cambridge, Mass. $5.2 million (3 years) "Electronic Sequencing in Nanopores" The objective of this project is to develop a general utility instrument to provide inexpensive sequenc...

Drugs from the deep blue

... also gone fishing for drugs that modulate calcium channels within cells, in collaboration with Isaac Pessah, ...eath, he said. Pharmaceuticals that affect calcium channels range from drugs given to organ transplant patients to suppress the immune system, to treatments for...

Freeze-dried mats of microbes awaken in Antarctic streambed

...ng held Aug. 7 to Aug. 12 in Montreal. The river channels under study feature intermittent streams that link...f glaciers, open expanses of barren ground, stream channels and permanently ice-covered lakes. The life forms inhabiting the area include microorganisms, mosses...

Cells direct membrane traffic by channel width

...rins, a class of proteins that form trans-membrane channels in cell walls in all forms of life. They allow for...nel. Side-by-side in computer-generated images the channels appear virtually identical. The Beckman teamed pushed glycerol through the channels, calculated the ...

Enzyme affects hypertension by controlling salt levels in body

...well known to lead to the activation of sodium ion channels in kidney cells. "The kidney plays a very importa.... "Sodium comes into the kidney cell through these channels and is then returned to blood circulation through another sodium transporter," he said. "The sodium ...

Water management in cells

...nciple is known as osmosis. Cells activate various channels to remove excess water and salt or osmotically act...hanges are facilitated by the presence of specific channels that transport water. Slow organic reaction In addition to water channels and ion channels, org...

Protein structure key for AIDS, cell function

...cium messenger molecules, each of which then opens channels for the release of calcium from specific stores, or reservoirs, within cell organelles. High intensity X-rays made it possible to pass photons through a protein crystal to reveal its structure. Cornell's synchrotron produces beams of X-rays millions...

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