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Tag: "changes" at biology news

Exploring the molecular origin of blood clot flexibility

...del that can then be used to predict the effect of changes at one scale on clot properties at other scales. Such a model should be useful for developing prophylactic and therapeutic treatments for many aspects of cardiovascular disease and stroke, suggest the investigators. ...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...consistent with clinical experience. For CI-1040, changes in the MEK pathway were most strongly associated with response. Predictors based on combinations of molecular correlates of response were able to quantitatively predict individual cell line responses. "The concordance of our markers of response ...

Carnegie Mellon University research shows how sensory-deprived brain compensates

...n-depth studies of brain plasticity in response to changes in how an animal senses its environment. Ultimately, we want to understand at the molecular level the dynamic between sensory use and neural plasticity," Barth said. ...

Prenatal cocaine's lasting cellular effects

...e altered D1 receptor trafficking may underlie the changes in neuronal architecture and behavior that Stanwood and others have previously observed. What remains to be determined, he cautioned, is whether D1 receptor localization is affected in humans exposed to cocaine prenatally. If found in humans,...

Warming oceans threaten Antarctic glaciers

...the oceans. These glaciers are vulnerable to small changes in ocean temperature, such as those that have occu...s surface allows us to see the increasingly subtle changes within the ice sheets that will govern their future sea level contribution."...

The desert is dying

...s. The focus has been on desert borderlands, while changes in sparse but important vegetation resources within the desert core have been neglected. ...

Twin studies reveal genetic components leading to cardiac and kidney disease

... study shows that both elevated blood pressure and changes to the kidney’s filters are caused by genetic variation at multiple points along the adrenergic pathway. Links between adrenergic activity and renal injury could lead to novel approaches to predicting, preventing, diagnosing and treating kidney dise...

Mummy's amazing American maize

...aize and even worshipped it. "Given the immense changes that took place in South America following the arrival of the Europeans it is surprising that this crop has remained unaltered for hundreds of years." Using the new facilities in the Manchester Interdisciplinary Biocentre ?a cross-faculty institut...

Researchers first to map gene that regulates adult stem cell growth

... provide a better understanding of the age-related changes that occur in stem cells." ...

Scientists find new genetic clue to cause of Alzheimer's disease

...tively short segments of DNA where disease-causing changes could lie. The study did not, however, identify specific genetic changes that result in Alzheimer's. Richard Mayeux, M.D., of Columbia University, Lindsay Farrer, Ph.D., o...

Global 'sunscreen' has likely thinned, report NASA scientists

...ll of aerosols is due to human activity or natural changes will have to await the planned launch of NASA's Glory Mission in 2008. "One of Glory's two instruments, the Aerosol Polarimetry Sensor, will have the unique ability to measure globally the properties of natural and human-made aerosols to unprecede...

Antarctic warming to reduce animals at base of ecosystem, shift some penguin populations southward

...els that most observers fear. It will make drastic changes in fragile ecosystems throughout the world, especi...ystem's response to warming in the region includes changes in both the krill's abundance and availability. "The data implies that there may be less food th...

Growth hormone is not the anti-aging bullet for healthy adults

...at the synthetic hormone was associated with small changes in body composition but not in body weight or other clinically important outcomes. Further, people who took GH had increased rates of unhealthy side effects such as soft tissue swelling, joint pain, carpal tunnel syndrome, and, in men, abnormal bre...

Cheaper, better disease treatments expected from faster approach to developing antibodies

...enes that produce antibodies are introduced. These changes result in slightly altered antibodies that may attach more strongly to a disease protein. The interaction between the antibody and the disease protein blocks the protein from doing harm in the body, effectively short-cutting a disease process. Ge...

Inflammation may play role in metastasis of prostate cancer

...ancer metastisizes or not is determined by genetic changes within the cancer cell itself. But this hypothesis didn't explain why metastases appear many years after the initial tumor. "Our findings suggest that promoting inflammation of the cancerous tissue, for instance, by performing prostate biopsies, ...

QUT scientists on the way to sifting out a cure for HIV

.... "With this in mind we have introduced radical changes to the membrane texture because it is the membrane texture which is crucial to the separation efficiency of the material," he said. "It is scientifically known that a mesh structure is the most efficient form of filtration and we are the first gro...

Notorious cancer gene may work by destroying messenger

...y an unidentified enzyme. Contact with this enzyme changes the properties of PMR1, and this enables it to join with, or bind to, its target mRNA. Peng then used monoclonal antibodies to isolate PMR1 and the enzyme while the two were bound together, capturing both. After separating the two, the investigat...

Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find

...ne to traumatic spinal cord injuries due to: (1) changes in bone quality with aging (2) increasing prevalence of cervical spinal stenosis with older age (3) an increased rate of motor vehicle accidents per mile driven It is also believed that these older patients have an increased risk of mortality...

Scientists discover a new risk factor for Alzheimer's

...de polymorphisms, or SNPs, which are single-letter changes in a gene's sequence. They found that the Caucasia...studied, but did not actually pinpoint the precise changes in the gene that contribute to disease. "Now we need to go back and look in the regions around the c...

Swell gel could bring relief to back pain sufferers

...cidity - and can be injected through a syringe. It changes to a stiff gel at physiological pH values - that is, once it enters the body - due to absorption of water by the particles. During their investigations, the research team injected the material into a damaged bovine intervertebral disc and increase...

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