Big differences in duplicated DNA distinguish chimp and human genomes
... as 20,000 base pairs. They found that most of the change to the overall genome landscape between chimps and humans can be attributed to large segmental duplications. Such large-scale genetic events have altered more total base pairs - about 2.7 percent of the genome - than differences from single base-pair...Modified collagen could yield important medical applications
...tems and biocompatible coatings. Yu's goal is to change some of collagen's biochemical or mechanical prope...h collagen, these attached agents can dramatically change the way collagen behaves in the body. For example, collagen normally attracts cells to close up a wo...Unusual antibiotics show promise against deadly 'superbugs'
...tems and biocompatible coatings. Yu's goal is to change some of collagen's biochemical or mechanical prope...h collagen, these attached agents can dramatically change the way collagen behaves in the body. For example, collagen normally attracts cells to close up a wo...Achilles heel of the herpes virus possibly found
...the University of Michigan Medical School may help change that. An estimated 45 million Americans have genital herpes and millions more have the more visible oral variety. Once someone is infected, they're infected for a lifetime. New medicines for herpes infection are badly needed; currently, antiviral dr...Blink, and the brain misses it
... whether the act of blinking--independently of any change in light normally caused by eyelid closure--would influence the level of light-activated brain activity. The UCL scientists found that when volunteers were blinking, brain activity was suppressed in areas that respond to visual input, even though th...To translate touch, the brain can quickly rearrange its sense of the body
...dy's sensory systems produced a rapid and profound change in another sensory system: The brain had changed the way it interpreted the signals from the sense of touch. These links between different bodily senses show that the brain constantly updates its internal map, and they shed light on the dynamic and f...Newly discovered genetic disease sheds light on body's water balance
...nine at position 137 (R137). The single nucleotide change resulted in one baby having a change from arginine to cysteine (R137C). This same mutation was carried by his mother. The other child had...Purdue scientists may have found key to halting spinal cord damage
...ls are responsible." When a spine is damaged, the change in its ability to function follows a well-defined pattern. In response to the initial shock, the spine immediately becomes completely nonfunctional but then starts to recover quickly. Over the course of the next few days, in response to the secondary...New tool reveals secrets of migrating cells
...s of development. "Two-photon imaging is going to change literally forever the way that we do biological science," said Witt, a developmental immunologist. "In the past, we'd take organs out, smush them up and basically do biochemistry in test tubes, or watch their behavior in a single layer of cells. It's...Scientists discover that three molecules may be developed into new Alzheimer's drugs
...give a little bit of symptomatic relief, but don't change the inexorable progression of the disease." He said that new insights made over the past decade help to understand the molecular and genetic basis of the disease and these can now be built upon for the development of treatments. "There is no doubt t...Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
...give a little bit of symptomatic relief, but don't change the inexorable progression of the disease." He said that new insights made over the past decade help to understand the molecular and genetic basis of the disease and these can now be built upon for the development of treatments. "There is no doubt t...Going To Extremes To Improve Human Health
...as Exercise and Movement Science, underwent a name change in July 2004.) "In this current day of rapid discovery in genetics and cellular biology, it is more important than ever that some attention be focused on the research-training of individuals who will make sense of the explosion of available informat......known specialist on this big cat, "is not due to a change in numbers, but simply reflects the additional eff...a more intensive analysis of the data. Results may change slightly, but we think it's safe to say that the population appears stable." ...Redesigned protein accelerates blood clotting
...p factor VIII) with the potential, if replaced, to change the performance of entire protein. Researchers proved the theory in the current study by swapping out a glutamic acid naturally occurring at a specific point in a calcium binding site on factor VIII with 19 different amino acids. One of the replaceme...'Punctuated' evolution in the human genome
...thin human pericentromeric regions ?areas of rapid change in genomic structure." Pericentromeric regions are sequences of DNA that lie in close proximity to the centromere, which plays a critical role in chromosomal separation during cell division. Pericentromeric regions contain an abundance of segmental ...Snapin: A protein with therapy potential for autism
...environment and elsewhere in the body. "We need to change cypin's function for branching but not its other functions," Firestein said. "Rather than a drug that blocks cypin, we need a drug that affects the binding between the cypin and snapin. This is easier to design and cypin can still function with the o...Pregnant women at higher risk for HIV, Uganda study finds
... other HIV risk factors. "It is unlikely that the change in HIV risk we observed is due to sexual behaviors. It may be attributed to hormonal changes affecting the genital tract mucosa or immune responses," said Gray. ...New clue to cocaine addicts' quirky behavior
... normal rats, they were significantly less able to change strategies when they were required to ignore the cue and always make a left or right turn to receive the reward. "Thus, although abnormally induced LTP by psychostimulants at limbic inputs might not interfere with learning a response strategy, it ma...Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure
... known as prenylation, produces a relatively large change in the chemical’s biological properties. “The mole...o the kinds of targets that it might interact with change completely.?/p> “We actually have in our hands now the ability to do things that a chemist might...... known as prenylation, produces a relatively large change in the chemical’s biological properties. “The mole...o the kinds of targets that it might interact with change completely.?/p> “We actually have in our hands now the ability to do things that a chemist might...