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Tag: "change" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...ding the development of breasts in girls and voice change in boys. As such, this research begins to answer one of the most vexing questions about human development: What causes puberty to begin? How is it that the full repertoire of reproductive hormones can exist at birth, go into hiding at about four to s...

Wisconsin scientists grow critical nerve cells

.... "You need to teach the [embryonic stem cells] to change step by step, where each step has different conditions and a strict window of time," says Zhang. "Otherwise, it just won't work." To differentiate into a functional spinal motor neuron, the stem cells advanced through a series of mini-stages, each r...

Jump-starting T Cells In Skin Cancer

...that the few T cells stimulated by the vaccine may change the local, suppressive environment of the tumor such that other T cells can snap out of their stupor and attack the tumor. ...

A new mechanism of regulating RNA degradation

...altering the amount of Staufen1 in the cell didn't change NMD function. Those observations, said Maquat, sent Kim on a hunt for what Staufen1 and Upf1 were doing. Looking at gene expression data available through the lab of Luc DesGroseillers, Ph.D. at the University of Montreal, they found that Staufen1 p...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...altering the amount of Staufen1 in the cell didn't change NMD function. Those observations, said Maquat, sent Kim on a hunt for what Staufen1 and Upf1 were doing. Looking at gene expression data available through the lab of Luc DesGroseillers, Ph.D. at the University of Montreal, they found that Staufen1 p...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...ving a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there. Roughly 10 percent of people have this double protein dose as well. In the Feb. 24 online versio...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...mponents of the growth medium have the capacity to change theimmunological characteristics of the human ES cells. More research isneeded to understand the optimal conditions for preparing human cellsfor therapeutic application.""We considered that one partial solution to the problem was to usehuman serum in...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...recognized by a person's antibodies. gp120's shape change is an important "escape mechanism" for HIV, allowing the virus to bind to and enter a cell before the immune system can "see" it, notes Harrison. "We can now compare the bound and unbound forms and try to understand whether there are any immunologic...

Timing is everything: First step in protein building revealed

...tion's starting point is found: first a structural change inthe ribosome complex, and then release of eIF1.L...arts, which likely affect ribosome function -- and change itstiming....

Ecological destruction fuels emerging diseases

...st, when there have been episodes of major climate change or mass extinction, and species have moved out of their areas of origin into other areas, there have been emerging diseases. Parasites have moved into new areas and they've jumped ship into new hosts." He will present his latest findings on February...

Bound for destruction: Ubiquitination protects against improper Notch signaling

... Notch signalingshows the ability to sense a small change in cell fate and amplify it,acting as a sort of contrast enhancement mechanism in cell fatedetermination. Notch is activated bya protease that is present ubiquitously in the cell membrane. What haslong remained a mystery, however, is the question of...

The secret lives of whales

...e ?which is us,?says Palumbi. “Ice ages, sea level change and even loss of local food sources did not interrupt their lives. Living in a fluid environment they could move to new areas of productivity and find food even as the climate around them changed.?/p> Palumbi compares the ability to read genes to...

Molecular machine may lead to new drugs to combat human diseases

... As introns proceed through their work cycle, they change shape by folding and bending. By crystallizing the complex at various stages, the scientists can determine and study its three-dimensional structure and learn how it is able to carry out its biochemical work. The Group I intron at its work cycle's m...

Sea skate experiment sheds light on human cell transport

...sh water. For humans, such a drastic environmental change would prompt an equally drastic physiological change: Our cells would take in too much water, diluting blood and other body fluids and rapidly causing death. So how do skates do it? Goldstein and Musch learned how cellular channels, or gates, spring...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...gnant brain tumors, the researchers found that any change in the functional diffusion map predicted 10 weeks...ying; and in some participants, researchers saw no change in diffusion. "In the end, we found if the diffusion changes in any way, up or down, it correlates ...

Scientists collaborate to assess health of global environment

... places, such as sub-Saharan Africa, environmental change is the principal factor causing poverty, according to the assessment. Implications The assessment represents more than a catalog of environmental problems, Mooney noted. By evaluating the trade-offs that accompany decisions about ecosystem services...

Experiments provide proof of how traveling in groups protects insects

... learn whether scientists can predict and possibly change the path of massive insect bands, he said. "In the United States nowadays, Mormon crickets just cost farmers and others a lot of money, but in parts of Africa and elsewhere, locusts can cause widespread famine because they consume crops, and the peo...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...ll known in obesity, for example, that even a tiny change in metabolic rate results in someone becoming obes...h as, 'OK, if I tweak this molecule, how does that change clathrin's role in all of this?'Ó "It's really quite exciting," Dr. Ryan said. "This new methodolog...

Experiments provide proof of how traveling in groups protects insects

... learn whether scientists can predict and possibly change the path of massive insect bands, he said. "In the United States nowadays, Mormon crickets just cost farmers and others a lot of money, but in parts of Africa and elsewhere, locusts can cause widespread famine because they consume crops, and the peo...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

...ne their shape. It also can show how thatshape can change when the protein interacts with another molecule.“This work required that we develop new NMR methods in order todetermine the shape of this protein, which undergoes changes as itinteracts with pIgR,?said Rensheng Luo, Ph.D., a post-doctoral fellowin ...

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