Mutant gene causes severe kidney disease in infants
..."Because PLCE1 is an enzyme, we have a much better chance of finding ways to modify its activity," Hildebrandt explains. "Using the zebrafish model, we can do high-throughput screening of many possible drug candidates for this form of nephrotic syndrome." Note for parents and physicians: Information o...Evolution of influenza A virus
...us diversity and evolution is strongly affected by chance events, such as reassortment between strains coinfecting a host or the introduction of a particular variant from elsewhere. These factors make predicting future patterns of influenza virus evolution more difficult, as vaccine strain selection then be...Vaccine-producing 'plant-factories'
... proteins with significant antigenic power. By chance The new route discovered by the CSIC team refu...ls that the starting point for this research was a chance discovery. The team had been investigating the metabolism of starch, a substance that is generated i...Diabetes slows nerve recovery after heart transplant
...pient is suffering from diabetes, there is still a chance for reinnervation--just at a slower speed," he added. "Unfortunately, there are no techniques developed yet that speed the nerve regeneration process," he said. Currently, nuclear medicine techniques (such as PET) are the only imaging techniques th...A silent pandemic: Industrial chemicals are impairing the brain development of children worldwide
...oal of public health protection. You have only one chance to develop a brain." ...Heavy smoking cuts women's chance of pregnancy -- even with donated oocytes
...r the uterus. But, heavy smokers have a much lower chance of achieving pregnancy. The fact that we see this ...d general pregnancy rate overall, but an increased chance of multiple pregnancy in those who do become pregnant." Dr Soares said, that as well as confirmi...Studies look at how genes affect antipsychotic drug response
..."Allowing patients with schizophrenia an increased chance at medication response literally could change their lives," Bishop said. "While we know a great deal about the pharmacology of antipsychotics like risperidone, there is still much to learn about their influence on cognition and brain function, as w...Novel vaccine shows promise against early-stage breast cancer
...ients will die. Even with improved therapies, the chance of a woman having breast cancer at some time in her life is still about one in eight. ...Scientists win grants to develop $1,000 genome sequencing technology
...ly challenging task, but I think we have as good a chance as any group to get there first." Huang's group was awarded $275,000 for one year with the possibility up to an additional $3 million over three more years if specified milestones are met in the initial experiments. Huang will be joined at the Jac...Seals protect brain, conserve oxygen by turning off shivering response on icy dives
...in requires less energy and oxygen and reduces the chance of damage caused by hypoxia, Folkow explained. Achieved while remaining active Seals have this physiological adaptation available just in case. This study found the seals can dive to more than 1,000 meters and for more than an hour. However, t...Poor athletic performance linked to vitamin deficiency
...t food groups like dairy or meat have an increased chance of deficiency. Such athletes are often concerned about maintaining a low body weight for sports like gymnastics and wrestling. "The most vulnerable people are often the individuals society expects to be the healthiest," said Manore. "There's a lot...Resistance and genetic sensitivity to sleeping sickness
...this human trypanosomiasis, or conversely a higher chance of a protector effect (2). The associations brought out between these mutations and the disease necessitate work to confirm this in different populations and environments. New investigations, particularly in genetic epidemiology, are currently bei...Abnormal overexpression of p53 is a predictive molecular biomarker
... progression." "Selecting those who have the best chance of responding to p53 tumor suppressor gene therapy also helps perfect clinical trial testing," Licato said. The researchers specifically found, in a subset of patients from phase II clinical trials, that 73 percent of patients with p53-positive tumo...'Tribbles' protein implicated in common and aggressive form of leukemia
...ren Keeshan, PhD; and colleagues found Tribbles by chance when looking for the molecular partners of another protein called Notch. Notch is a molecular switch of sorts, activating gene transcription in the nucleus of many types of cells, and depending on the biochemical context, turns certain pathways on an......the bad news is that they are not being given that chance in many parts of their range," said WCS’s noted big-cat researcher Dr. Alan Rabinowitz. Earlier this year, WCS launched a new program called "Tigers Forever" that pledges a 50 percent increase in tiger numbers in key areas over the next decade. ...Special chip provides better picture of salmon health
... for the conservation of wild salmon, offering the chance to reverse the decline in Britain's salmon population." ...Cardiologist's 'living chip' changes science of disease monitoring
...patient remains healthier, and greatly lessens the chance of a hospital stay. The initial application for this technology is expected to involve pharmaceutical companies, which could use the biological chips to test potential drugs in the lab more quickly and accurately. In later generations, the chip ult...Proteins anchor memories in our brain
...more insulin in the thymus, then there is a better chance that potentially destructive insulin-specific T cells will encounter insulin as self and be filtered out." In the thymus, immature T cells display on their surface many thousands of unique receptors, generated by random gene rearrangements. This ...Autoimmune disease triggered if T cells miss a single protein early on
...more insulin in the thymus, then there is a better chance that potentially destructive insulin-specific T cells will encounter insulin as self and be filtered out." In the thymus, immature T cells display on their surface many thousands of unique receptors, generated by random gene rearrangements. This ......ve their own health before pregnancy have a better chance of delivering a robust, healthy baby. Three important measures include: Managing conditions such as diabetes, hypothyroidism, inherited disorders, obesity, sexually transmitted diseases, and oral health; Protecting one's health through suppleme...