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Tag: "chain" at biology news

Hantavirus found in African wood mouse

... technique called reverse-transcriptase polymerase chain reaction (RT-PCR), the scientists searched each sample for a segment of RNA characteristic of hantaviruses. They found a match in one of the four African wood mice in the study. After finding the virus, the group cloned and sequenced it and compared...

Scientists force viruses to evolve as better delivery vehicles for gene therapy

...ons in the genes through an error-prone polymerase chain reaction (PCR) coupled with a test tube recombination technique. After reassembling the mutant viruses inside their capsids, they introduced them to blood serum pooled from rabbits immunized against AAV, and thus containing many types of antibodies t...

The diversity of marine life in the Gulf of Maine region is much greater than previously thought

...r, seaward of Georges Bank, scientists exploring a chain of extinct, undersea volcanoes known as the New En...e humpback whale are at the top of the marine food chain and depend on multiple species lower in the chain. For example, a humpback whale may need to eat a ...

For the first time: Longevity modulated without disrupting life-sustaining function

...tory functions in the body. In worms, however, the chain of signals is set in motion when a single receptor on the cell surface is matched to an insulin-like signal. "If you were to interfere with insulin signaling in humans in order to prolong life, you would induce diabetes right away," cautioned gradu...

Protein receptor cools passion of 'kiss and run' nerve cells

...its are released, they activate the next step in a chain of events that move signal information through the nerve cell. Alford's lab previously discovered that the beta-gamma subunit affects the molecular machinery that causes release of neurotransmitter -- the amino acid glutamate. "It's very fast," sai...

A step forward in the fight against bacterial infections

...inates the bacteria from our body. Of course, this chain of reactions is strictly controlled, because excessive inflammation can lead to lethal shock. Mice that are able to cope with acute inflammations Tina Mahieu and her colleagues from the research group led by Claude Libert are working with mice t...

First link of oral bacteria and preterm birth found in human

...tudied. Since new techniques like PCR (polymerase chain reaction) became available to track the DNA of the bacteria, it now allows for the study of those other bacteria. Now that a link was found, Han plans to more research to answer questions that have arisen from this finding. ...

Prenatal nicotine exposure reduces breathing response of newborns...

...tudied. Since new techniques like PCR (polymerase chain reaction) became available to track the DNA of the bacteria, it now allows for the study of those other bacteria. Now that a link was found, Han plans to more research to answer questions that have arisen from this finding. ...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...emase, or AMACR. This protein metabolizes branched chain fatty acids, cholesterol metabolites and enhances the activity of ibuprofen. The AMACR protein is overexpressed in some cancers such as prostate, colon and precancerous colorectal adenomas, or polyps, though it is expressed very little in normal ti...

Technique speeds up detecting, treating wound bacteria

...ods though a technique called real-time polymerase chain reaction, the physician-researcher from the West Los Angeles Veterans Administration Medical Center can drastically cut the time it takes for lab personnel to figure out just what bacteria they're dealing with. "The big advantage of real-time PCR i...

Chimpanzees can transmit cultural behavior to multiple 'generations'

Transferring knowledge through a chain of generations is a behavior not exclusive to huma...hows behavior and traditions can be passed along a chain of individual chimpanzees. These findings, based upon behavioral data gathered at the Yerkes Field ...

New genes implicated in rheumatoid arthritis

...sing immunohistochemistry and real-time polymerase chain reaction, they confirmed the expression of the most significantly over-expressed genes in synovial tissues. In addition, they compared gene expression in synovial tissue of the RA patients with gene expression in synovial tissue of patients with oste...

Many cleaners, air fresheners may pose health risks when used indoors

...eaners and air fresheners available at any of five chain retail outlets in Northern California, then examined the labels and advertising claims (e.g. "pine-scented") for these products and reviewed available product data sheets. Based on this information, they selected the 21 products most likely to contai...

Radiation-killed bacteria vaccine induces broad immune response in mice

...es with reliable electricity, maintaining the cold chain is rarely a problem. The same is not true in less ...se, explains Dr. Raz, thereby eliminating the cold chain requirement. It is also possible that a strategy based on irradiation-inactivated whole pathogen...

Insect predation sheds light on food web recovery after the dinosaur extinction

... open to opportunism, and in a few places the food chain became unbalanced and unstable. At Castle Rock, plants flourished in the warm wet climate and without insect predatory pressure -- possibly because their rainforest-type leaves were already thick, tough, and hard to eat -- plant species proliferated...

Cornell researchers find serious fish virus in Northeast for first time

... a rapid diagnostic test, called a PCR (polymerase chain reaction), which would amplify and detect small amounts of viral DNA or RNA in a blood or tissue sample. Although no management decisions have yet been made, the DEC could recommend that boaters clean their boats before traveling from one body of ...

New strategy rapidly identifies cancer targets

...n many cancers. In healthy cells, they help form a chain of signals that prompt normal cell growth and division. Sometimes, though, a tyrosine kinase gets stuck in an "on" position, driving out-of-control cell division and, ultimately, cancer. This potentially devastating kinase activation carries a callin...

Basic work on E. coli identifies two new keys to regulation of bacterial gene expression

...oter regions are specific sequences within the DNA chain that tell RNA polymerase when and where to begin transcription, and how much product to make from specific genes. Gourse's group found that there is a specific region within DNA promoters that makes contact with a highly conserved but previously un...

'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage

... off one of the pairs of bases that make up DNA, a chain of damage begins that causes "lesions" in the DNA. These lesions, when replicated in the copying mechanisms of DNA, can lead to serious disorders such as cancer. The research, just published in the Proceedings of the National Academy of Sciences (PN...

UCI scientists find chlorine may contribute to ozone formation

...power plant emissions, contributing to the complex chain of reactions that leads to ozone formation. The primary cause of urban ozone is the reaction of hydroxyl radical (OH) with hydrocarbons and nitrogen oxides. OH is a highly reactive molecule made of oxygen and hydrogen that forms photochemically in ai...

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