Chemists create 'Superbowl' molecule; May lead to better health
...and out. This is ideal if you're trying to capture certain molecules and hold them until they're ready for release, the researcher says. Superbowl molecules are similar in function to buckyballs, the experimental soccer-ball shaped molecules also known as fullerenes (C60), which also show promise for drug d...Wisconsin scientists grow critical nerve cells
...tor neuron development to another. But once past a certain point, Li found that the cells kept veering off toward different cellular destinies. After hundreds of unsuccessful variations of growth factors and morphogens, Li was struck by an idea: Why not apply a chemical known to be necessary for a later stag...Man and mouse share genome structures
...ith Affymetrix. They isolated the DNA regions with certain major methyl and acetyl tags, and used new microar...e implications for understanding mechanisms behind certain cancers, Bernstein believes. For example, proteins that place methyl groups on histones can, when mu...Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...ides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, report that the harmful effects of saturated and trans fats are set in motion by a biochemical switch, or co-activator, in liver cells called PGC-1beta. Until now, scie...UAB scientists discover the origin of a mysterious physical force
...ration force that acts when water is surrounded by certain types of electrostatically charged molecules, such as DNA and some biological compounds, and when thin films form in detergents. The discovery has been published in today's edition of Physical Review Letters. Water is the solvent in which most physi...Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
...finding that broadens our insight intothe cause of certain kinds of UV-induced skin cancer, researchers atErasmus University Medical Center (Rotterdam, The Netherlands) haveemployed an evolutionarily ancient enzyme-repair system to identify theprincipal type of DNA damage responsible for the onset of skin-tu...New binding target for oncogenic viral protein
... the cell. Fbw7 recognizes a destruction signal on certain proteins that need to be degraded and brings them in close proximity to the enzymes that attach ubiquitin. The proteins recognized by Fbw7 play key roles in cell division, cell growth, differentiation, and cell death. "These proteins are also some o...Fox Chase Cancer Center scientists identify immune-system mutation
...ss against various immune disorders, allergies and certain cancers, such as those of the blood and bone marrow, that involve a compromised immune system. "As one example, a decrease in the number of CD4 T cells is the primary mechanism by which HIV causes AIDS," Kappes said. The helper-deficient mice his t...Controversial drug shown to act on brain protein to cut alcohol use
...the 1960s drugculture, and evidence of toxicity to certain nerve cells in rodentstudies have discouraged careful studies of its clinical potentialagainst drug and alcohol addiction. The FDA has not approved use ofIbogaine in the U.S.Scientists at UCSF's Ernest Gallo Clinic and Research Center have nowshown d...Termites feed through good vibrations
...e known to prefer eating particular sizes of wood; certain drywood termites prefer small blocks, presumably to avoid competition. With Professor Joseph Lai and his students from the University of New South Wales at the Australian Defence Force Academy, Dr Evans investigated how the blind insects measured pie...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...arly, this amoeba has genes that allow it to sense certain facets of its environment and respond to those cue...damage human cells and cause disease, the level of certain bacteria in the colon can be an important determinant of the amoeba's virulence. Biomedical scienti...UW's Rosetta software to unlock secrets of many human proteins
...quences into thousands ofpossible shapes, based on certain protein folding "rules" known byscientists. These rules are summarized in the program and are termedthe "Rosetta score." The program tries a great many conformations andreturns those with the lowest Rosetta scores; these conformations comeclosest to ...Plants, animals share molecular growth mechanisms
...ell and allow it to grow, and they determine where certain structures in a cell are positioned and how plants...er, scientists don't know the specific function of certain actin filaments. The molecular tools Szymanski's research team developed will help scientists learn ...Researchers find how protein allows insects to detect and respond to pheromones
...quences into thousands ofpossible shapes, based on certain protein folding "rules" known byscientists. These rules are summarized in the program and are termedthe "Rosetta score." The program tries a great many conformations andreturns those with the lowest Rosetta scores; these conformations comeclosest to ...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
...,including identifying novel genes associated with certain cancers,classifying tumors, and predicting patient outcome. So far, though,microarray studies have been performed by individual institutions.Evaluation of the potential clinical use of microarrays may requirelarger studies carried out in multiple loc...Scientists detect probable genetic cause of some Parkinson's disease cases
...kinson's disease eachyear. The disease occurs when certain nerve cells die or becomeimpaired and can no longer produce dopamine, a brain signaling chemical(neurotransmitter). Without it, individuals can develop tremor ortrembling in hands, arms, legs, jaw, and face; rigidity or stiffness ofthe limbs and trun...New Technique for Tracking Gene Regulators
..., liver, or blood ?as well as what mightgo awry in certain conditions like cancer. TheBrookhaven scientists,...umans, and genes that may play an importantrole in certain cancers.“This technique can be applied to any protein that binds to specificsequences in the DNA and...Bacteria collection sheds light on urinary tract infections
...e multiple benefits such as aiding in digestion of certain nutrients. However, E.coli is also commonly associated with illnesses caused by eating undercooked beef or drinking contaminated water. Without access to the large collection of bacteria strains from the Gastroenteric Disease Center, it would have b...HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs
...lert for multiple drug therapy situations, because certain drug-drug combinations could trigger the adverse heart side effects. Background of the Discovery Dr. Badley's research group earlier discovered that protease inhibitors affect "pore function" of "channels" in a specific cell type they were studying......ibitory response and showed that it was similar to certain pro-inflammatory molecules produced in the body in response to injury or infection. The authors now plan to assess whether cells from allergy-prone people are more sensitive to the effects of the pollen-derived compound than those from non-allergic i...