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Tag: "central" at biology news

Drug triggers body's mechanism to reverse aging effect on memory process

...airment and may be useful for treating a number of central nervous system disorders, such as Alzheimer's dise...rder to be effective. Most drugs used to deal with central nervous system disorders, such as Parkinson's disease, are only effective when they are in the body....

Researchers map out networks that determine cell fate

...ing the circuitry that controls these decisions is central to learning how different kinds of stem cells deve...tor called PU.1 that acts as the primary signal, a central genetic switch to initiate development of myeloid progenitor cells. Other researchers identified a r...

Widespread elephant slaughter discovered in Chad

...tern Chad makes up part of a Texas-sized region of central Africa that until the 1970s was one of the contine...now one of the last bastions of wildlife in all of central Africa, thanks to funding from the EU. Fay led a survey team also commissioned by the Chadian gover...

Scientist-astronaut sends T-cells into space

...pace." T-cells are white blood cells that play a central role in the body's immune response. They are a target of human immunodeficiency virus (HIV), which suppresses them. When an HIV patient's T-cell count falls below 200, he or she is susceptible to the dangerous infections that are the symptoms of acqu...

Genetically altered mice no longer like cocaine

... messenger vital to the regular functioning of the central nervous system. Under normal circumstances it flows into and out of neurons. But cocaine blocks dopamine transporters from taking up dopamine, leaving it outside the cells, which excites the nervous system to the point where a cocaine user feels a h...

Researches discover gene critical for protection against septic-shock-induced death

...ilure or death. Controlling inflammation is thus a central focus of treating sepsis. Researchers have been hunting for novel host genes that regulate inflammation as potential targets for the next generation of sepsis therapies. The incidence of sepsis in the United States ranges from 400,000 to 750,000 case...

Experimental drug reverses key cognitive deficits, pathology in Alzheimer's

...he amygdala. In experiments that demonstrated the central role of M1 receptors in AD-like pathology, the researchers also tested the effects on the mice of another drug, dicyclomine, that blocks M1 receptors. They found that both normal and knockout mice treated with the drug showed the characteristic learn...

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

...ells ?"immature" cells that can differentiate into central nervous system cells ?have the ability to target a...02, the scientists reported that they had produced central nervous system cells from stem cells derived from bone marrow. Because these stem cells originate in...

Anti-inflammatory drug's potentially deadly side effect found to be rare

... crossing membranes that protect the brain and the central nervous system. Prior to the studies that were hal...valuated patients and either sent the results to a central database if they suggested little chance of PML or, if indications of potential PML were detected, t...

Study finds 60 new genes controlled by DNA snippet

... comprise just about 2 percent of all human DNA. A central question in genetics has become: what does the remaining 98 percent of human genetic material do? Regulatory sequences are emerging as an important part of the non-gene majority of human genetic material, once thought of as "junk DNA." A new frontie...

Dying of excitement

...major excitatory neurotransmitter in the mammalian central nervous system (CNS) -- in the plasma and cerebral spinal fluid. One possible explanation for this glutamate build-up, reported online on March 6th in The Journal of Experimental Medicine, is a mutation in the gene encoding the glutamate transporter...

Evolution mystery: Spider venom and bacteria share same toxin

...rown recluse and their relatives. If this motif is central to protein function, treatments designed for the spider bites may also work for treating problems caused by the corynebacterial toxin," she added. ...

Big hips, big belly? It's in your genes, Joslin-led study shows

...MS), a chronic autoimmune disease that affects the central nervous system, according to background informatio...stein-Barr virus causes the body to attack its own central nervous system, as it does in MS. "The mounting evidence that relates Epstein-Barr virus infection ...

Epstein-Barr virus may be associated with multiple sclerosis

...MS), a chronic autoimmune disease that affects the central nervous system, according to background informatio...stein-Barr virus causes the body to attack its own central nervous system, as it does in MS. "The mounting evidence that relates Epstein-Barr virus infection ...

Hap1 protein links circulating insulin to brain circuits that regulate feeding behavior in mice

... 1 print edition. The hypothalamus serves as the central switching control for neural signals that regulate food intake and energy balance. Hormones such as insulin and leptin, which circulate in the blood plasma, are known to play an important role in regulating the brain's feeding signals, but scientists...

BioMed Central launches Biology Direct

...s long been interested in open access and has been central in the development of PubMed, GenBank and PubMed Central, the NLM's open access repository for literature in the life sciences. Lipman and Koonin, speaking on the eve of the journal's launch, explain the motivation for establishing Biology Direct: ...

Most human-chimp differences due to gene regulation ?not genes

...s have suspected that gene regulation has played a central role in human evolution," said Kevin White, Ph.D., associate professor of genetics and ecology and evolution at Yale and senior author of the study. "In addition to lending support to the idea that changes in gene regulation are a key part of our evo...

Blood flow in brain takes a twist, affecting views of Alzheimer's

...s. But it's turning out that astrocytes may play a central role in many human diseases," said neuroscientist Maiken Nedergaard, M.D., Ph.D., who has produced a string of publications fingering astrocytes in diseases like epilepsy and spinal cord injury. "In a disease like Alzheimer's, for instance, perhaps ...

Study reveals classic symbiotic relationship between ants, bacteria

...e relationships between certain species of ants in central and South America, the fungus they cultivate for food, the parasite that invades the fungus, and the bacteria that the ants harbor to fight the parasite. The phenomenon is a classic example of mutually beneficial symbiosis, and Currie views it as a ...

'Dead zone' summer killed billions of ocean state mussels

.... In a survey of nine mussel reefs located in the central bay, researchers found one reef completely wiped out. Of the remaining eight, seven were severely depleted. The ecologists estimate that the number of mussels that died was roughly 4.5 billion, or about 80 percent of the reefs' population. Just one ...

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