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Tag: "centers" at biology news

Buckyballs boost antibody's chemotherapy payload

...ong, covalent bonds -- tend to block the targeting centers on the antibody's surface. If an antibody is modified with too many covalent bonds, the chemical changes will destroy its ability to recognize the cancer it was intended to attack. Wilson said the team from Rice and M. D. Anderson had planned to ove...

Smooth sailing: 'cruise ship virus' tackled by UH, Baylor College of Medicine

...This RCE is part of a national network of 10 other centers that support research focused on countering threats from bioterror agents and emerging infectious diseases. Each is comprised of a consortium of universities and complementary research institutions serving a specific geographical region. UH and the...

First-ever genomic test predicts which lung cancer patients need chemotherapy to live

..., will enroll more than 1,000 patients at multiple centers in the United States and Canada. "If we can use the test to increase patient survival by even 5 percent, we would save 10,000 lives a year," Harpole said. The Duke researchers developed the test by analyzing the activity of genes from early-stag...

Lost in thought: Brain research

...eir study suggests that the brain's self-awareness centers do not function as a critical element that allows perceptual awareness of the outside world. Rather, the self-related areas of the prefrontal cortex appear to be engaged specifically when we are aware both of the sensory experience and of ourselves a...

Making a face: A new and earlier marker of neural crest development

...cells that go on to form the face, skull and nerve centers of the head and neck in vertebrates is determined much earlier in development than previously thought, and is independent of interaction with other forming tissues, according to a recent study published in the journal Nature. The collaborators at Y...

Scientists solve sour taste proteins

... chemical and triggering signals sent to the taste centers of the brain. In their study, the researchers used fluorescent tags to label the subsets of cells that are known to be responsible for bitter, sweet, and umami taste, as well as the subsets of cells that express PKD1L3 and PKD2L1. By "reading" the ...

Meth promotes spread of virus in HIV-infected users

...edicine and Biomedical Sciences. His research centers on dendritic cells, which serve as the first line of defense again pathogens, and two receptors on these cells -- HIV binding/attachment receptors (DC-SIGN) and the meth-specific dopamine receptor. Dendritic cells overloaded with virus due to the act...

Major initiative proposed to address amphibian crisis

... initiative, which may include a global network of centers for amphibian recovery and protection. Support from individuals, government agencies, foundations, and the conservation community will be sought, the researchers said in their report. Amphibians have been around for more than 300 million years, th...

Higher levels of obesity associated with greater health risks

...ight status in 90,185 women recruited from 40 U.S. centers for the Women's Health Initiative-Observational Study who were followed-up for an average of 7.0 years (Oct. 1993 to Aug. 2004). The researchers found that extreme obesity prevalence differed with race/ethnicity, from 1 percent among Asian and Pacif...

New study reveals structure of E. coli multidrug transporter protein

...red to $84 for first-line drugs." In addition, the centers noted, second-line drugs need to be taken for longer periods of time-from 18 to 36 months-and may require substantial patient monitoring, making these treatments difficult if not impossible to "be available in many of the resource-poor nations where ...

New study calculates millions of years saved in lives of AIDS patients

...eagues at Massachusetts General Hospital and other centers appears at a time the world contemplates the 25-year anniversary of the first reported cases of AIDS and celebrates the 10-year anniversary of the use of multi-drug antiretroviral combinations for the treatment of HIV infections (also known as highly...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...titute of Harvard and MIT, and other collaborating centers have unveiled a new, systematic approach to drug discovery that matches diseases with potential treatments using a universal language based on cells' distinctive gene activity profiles, or "signatures." A set of three articles being published in t...

Scientist works to improve treatment for brain tumors

...II) involving 190 patients at 40 different medical centers worldwide. The results are expected later this year. Since the development of the original drug, Debinski has learned more about the structure of IL13, its receptors, how the cytotoxin binds to it and how the biological properties of tumors may affe...

Researchers find that bumblebees' flower choice matters

...the National Science Foundation, Karron's research centers on the reproductive biology of monkey flower, a wetland plant native to Wisconsin. Karron's lab uses several innovative methods of tracking monkey flower mating, and all hinge on where the pollen comes from. Pollen allows the flowers, which contai...

UWM brain research supports drug development from jellyfish protein

...or a new drug to be developed. Moyer's research centers on brain changes that occur as a result of aging. Specifically, he is interested in the part of the brain called the hippocampus, which is responsible for forming new memories. These capabilities not only deteriorate in neurodegenerative disorders su...

Scientists work to identify genes that contribute to early heart attack risk

...edical Center and colleagues at four other medical centers have launched a $10 million multi-year study to id...orest and lead investigator. Other participating centers are Cedars Sinai Medical Center, Louisiana State University (LSU) Health Sciences Center in New Orle...

High dopamine transporter levels not correlated with ADHD

...he ventral striatum that is one of the main reward centers in the brain. In a dorsal striatum region known as the putamen, which plays an important role in habits and is also involved with attention, dopamine transporter levels did not differ between the two groups. In both groups, levels of dopamine trans...

Second opinion yields treatment changes for half of patients

...hed one of the first multidisciplinary breast care centers in 1985 to provide comprehensive diagnosis and treatment for women with benign or malignant disease. U-M currently has multidisciplinary clinics in 11 tumor types. ...

Molecular 'on/off switch' controls immune defenses against viruses

...uenza and the common cold." Dr. Gale's research centers on studying the mechanisms viruses use to evade immune defenses. Of particular interest is the hepatitis C virus, a blood-borne infection transmitted by intravenous drug use, blood transfusions and sexual contact. It affects 4 million U.S. residents ...

St. Jude finds clues to hearing loss from chemotherapy

...at includes universities, several medical research centers and a national laboratory. The consortium used ENU, a chemical that causes random mutations in sperm of mice that were subsequently mated with females. Offspring of this mating carried mutations in one or more specific spots in their DNA, Zuo explai...

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