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Tag: "cells" at biology news

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...mphoma is a cancer in which the antibody-producing cells (B lymphocytes) multiply uncontrollably and crowd ...ur in precancerous B lymphocytes, permitting these cells to become cancerous. This mutation inactivates the function of p53, a gene that orchestrates the abi...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...ould be designed to tweak the wiring plan of human cells to more effectively treat diseases while also gene... now able to open the hood of yeast, worm, and fly cells and look at the protein interactions inside," said Trey Ideker, a bioengineering professor at the Un...

Scientists discover that host cell lipids facilitate bacterial movement

...lled filopodia. These filopodia push into adjacent cells and are ingested by them. The bacteria then enter ...veries provide additional fundamental clues as how cells move." These findings may also open the door to using PI3-kinase inhibitors or other agents that lo...

UF Researchers Map Bacterial Proteins That Cause Tooth Loss

...s, shedding light on how it interacts with healthy cells in order to thrive, according to dental researchers from the University of Florida and the University of Washington. They describe their findings in the current issue of the journal Proteomics. “Determining which proteins are expressed in greater le...

UCSD team discovers specialized, rare heart stem cells in newborns

The first evidence of cardiac progenitor cells ?rare, specialized stem cells located in the newborn heart of rats, mice and humans ?has been shown by researchers at the Universi...

Scientists solve structure of key protein in innate immune response

...fer. Not only do these findings shed light on how cells recognize pathogens, they also may also lead to the development of drugs to help treat septic shock, an often fatal systemic bacterial infection that is triggered by LPS. "Pharmaceutical companies have tried to develop anti-septic shock agents for a...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

...ancerous cells. The radiation zaps these malignant cells with minimal exposure to normal tissues. With the Bexxar therapeutic regimen, a patient receives an injected test dose of radioactive Bexxar to determine how that patient's body processes the tagged antibody. Nuclear medicine scans are used to asses...

Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals

...gie Mellon University scientists have "programmed" cells to make their own contrast agents, enabling unprec...f molecular biology tools we can now enable living cells to change their MRI contrast via genetic instructions." "The new imaging method is a platform techn...

Gene therapy for Parkinson's disease moves forward in animals

...ene therapy in two separate studies to renew brain cells and restore normal movements in monkeys and rats w...neurotrophic factor, is believed to preserve brain cells and could provide protection against Parkinson's disease. But its use has been debated since trials ...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

...s a form of molecular insulation that allows nerve cells to send impulses to one another more effectively. Such pathways showed different responses to alcohol in one mouse strain versus the other. As a result, Miles and his colleagues were able to formulate new hypotheses about how the brains of the mouse ...

Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments

...sels by promoting the proliferation of endothelial cells in the heart. New blood vessels are required to provide oxygen-carrying blood to heart muscles to compensate for the blocked heart arteries. The subsequent, improved blood flow relieves the painful symptoms of angina. "The process of growing new bl...

How an AIDS-Related Cancer Unleashes Inflammation

...KS) indicated that the abnormal growth of infected cells required the overproduction of cytokines ?immune system proteins that trigger the cell's inflammatory response. A central question, he said, has been how does the Kaposi's sarcoma-associated herpesvirus that causes KS initiate cytokine production? "...

PCRM develops world's first cruelty-free insulin assay

...h insulin antibodies grown in vivo--literally from cells injected into the abdomens of live mice--or we could use kits containing antibodies produced from cells cultured with fetal calf serum. Neither was acceptable to us." The answer? Develop an in-vitro, or ...

Sequencing of marine bacterium will help study of cell communication

...ist advance her research on quorum sensing, or how cells communicate and function as a community. Research...bacteria use quorum sensing. Stevens explains that cells release autoinducer molecules. The numbers of these signal molecules increase with cell density, unt...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

...hip contains approximately 5,000 microscopic solar cells that convert light into electrical impulses. The p...eplace damaged photoreceptors, the "light-sensing" cells of the eye, which normally convert light into electrical signals within the retina. Loss of photorec...

Special Imaging Study Shows Failing Hearts Are 'Energy Starved'

...icals and their chemical reaction rates within the cells of various tissues. They first performed MRS on 14 healthy volunteers to measure cardiac CK flux at rest and with pharmaceutically induced stress to determine whether increased energy demand during stress increases the rate of ATP synthesis through C...

New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines

...s activate innate B cells, the body destroys the B cells to protect against autoantibodies that could cause... response to HIV outer coat proteins from innate B cells to adaptive B cells. Alternatively, we can develop ways to induce that first line of polyspecific an...

Antibiotic might fight HIV-induced neurological problems

...ve reported that this antibiotic can protect brain cells in animal models of other diseases -- multiple scl... in the same way and use the same tricks to infect cells and outwit treatments, but SIV infects only non-human primates, and HIV only infects people. Antiret...

Ophthalmologists implant five patients with artificial silicon retina microchip

...hip contains approximately 5,000 microscopic solar cells that convert light into electrical impulses. The p...eplace damaged photoreceptors, the "light-sensing" cells of the eye, which normally convert light into electrical signals within the retina. Loss of photorec...

Protein offers way to stop microscopic parasites in their tracks

...illion people per year through damage to red blood cells and clogging of the capillaries that feed the brain and other organs. Cryptosporidium, which causes diarrhea, vomiting and other symptoms, is one of the most common causes of water-borne disease in the world. "These other parasites are more devastat...

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