Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
...ke global views of (chromosome packaging) in human cells holds tremendous promise for unraveling the myster...hat contains "on" tags. DNA is the same in all the cells in our body. What makes the cells do different jobs is that different genes are turned on. For examp...New research questions basic tenet of neuron function
...hallenge one of the established views of how nerve cells communicate with one another. Every time we move, feel emotions, think or remember, the nerve cells, or neurons, in our body transmit messages to one another via chemical signals called neurotransmitters. Within neurons are tiny organelles called sy...Vital step in cellular migration described by UCSD medical researchers
... molecular step in cell migration, the movement of cells within the body during growth, tissue repair and the body's immune response to invading pathogens, has been demonstrated by researchers in the University of California, San Diego (UCSD) School of Medicine. Published in the March 27 online edition of ...U-M scientists find genes that control growth of common skin cancer
...mon form of cancer ?anduncovered a subset of tumor cells that were resistant to inhibition ofthe Hedgehog p...ugosz and colleaguesturned Gli2 off, the BCC tumor cells stopped growing and wereeliminated by a programmed cell death process. These results areconsistent w...Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
As you read this, cells in your eye are transmitting information to your brain, while cells in your heart and arteries work just as hard to keep that brain alive. Every one of these cells -- a...Two compounds that zero in on cancer cells spreading throughout the body, while ignoring prim...ented 91 to 99 percent of metastatic breast cancer cells in mice, and are the first to target only metastatic cells. "They're unbelievably effective, and in...Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
...treptococcus pneumoniae bacteria use to latch onto cells lining thethroat and lungs. The protein, called CbpA, binds to a molecule on thecell called pIgR, which takes antibodies from the bloodstream on oneside of the cell and transports them to the other side. There itreleases the antibody at the lining of...Critical role in programmed cell death identified
...ndria, the cellular power plant, in prompting worm cells to self destruct. These results unify cell death m...w it seems that there is really one way of killing cells and it involves these mitochondria. Using genetics, we could rigorously show that mitochondria are p...New comparative toxicogenomics database
...treptococcus pneumoniae bacteria use to latch onto cells lining thethroat and lungs. The protein, called CbpA, binds to a molecule on thecell called pIgR, which takes antibodies from the bloodstream on oneside of the cell and transports them to the other side. There itreleases the antibody at the lining of...Taking Aim With Nanoparticle PEBBLEs
...es, and others to deliver a deadly cargo to cancer cells when triggered by exposure to light. Unlike chemo...herapy drugs that attack tumors by invading cancer cells and disrupting their DNA, PEBBLEs never enter the cells they target. Instead, they attach to the out...ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors
...ts to quench free radicals and potentially protect cells and tissues in the body from oxidative damage. Now, McGraw says, he's interested in learning more about the connection between the red colors and anti-oxidants within and among parrot species, as well as "to specifically explore the balance of natur...Genetically modified natural killer immune cells attack, kill leukemia cells
Natural killer (NK) immune system cells can be genetically modified to brandish a powerful...uthor of the Blood report. Progress in adapting NK cells to the treatment of ALL had been significantly hampered because researchers were not able to grow la...UCSD researchers maintain stem cells without contaminated animal feeder layers
The growth and maintenance of human embryonic stem cells in the absence of contaminated animal products has... A are capable of maintaining human embryonic stem cells in a continuous undifferentiated state, ready for research. Undifferentiation means the stem cells h...Transport System Smuggles Medicines Into Brain
...ts to quench free radicals and potentially protect cells and tissues in the body from oxidative damage. Now, McGraw says, he's interested in learning more about the connection between the red colors and anti-oxidants within and among parrot species, as well as "to specifically explore the balance of natur...Placenta Is A Rich Source Of Blood Stem Cells
... development, are able to generate more blood stem cells and can give rise to a complete blood system when ...into an adult. Unlike other sites where blood stem cells are found during embryonic development, such as the liver, the stem cells in the placenta can increa...Probing The Promise And Perils Of Nanoparticles
...they can completely destroy the membranes, killing cells in the process. But the damage can be prevented by...Holl. But early results of experiments with living cells suggest that the same types of nanoparticles that punch holes in model membranes also damage membran...Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
...ul animal studies, a novelvaccine that uses immune cells as factories to produce Her2/neu proteinmay offer ...n asa delivery system for proteins from the cancer cells that are to betargeted by the animal’s immune system.The basis for this new vaccine is an RNA virus ...Highly adaptable genome in gut bacterium key to intestinal health
...25, 2005 issue of the journal Science. "Bacterial cells in the human gut number close to 100 trillion," says Jeffrey Gordon, M.D., director of the Center for Genome Sciences at Washington University and professor of molecular biology and pharmacology. "Together, these microbes can be viewed as a 'microbia...A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...ul animal studies, a novelvaccine that uses immune cells as factories to produce Her2/neu proteinmay offer ...n asa delivery system for proteins from the cancer cells that are to betargeted by the animal’s immune system.The basis for this new vaccine is an RNA virus ...Gene Therapy For Parkinson's Disease Moves Forward In Animals
...ene therapy in two separate studies to renew brain cells and restore normal movements in monkeys and rats w...neurotrophic factor, is believed to preserve brain cells and could provide protection against Parkinson's disease. But its use has been debated since trials ...