Novel antiviral technology inhibits RSV infection in mice
...sue ofthe journal Nature Medicine.RSV infects lung cells and can be life-threatening in very youngchildren,...degradable particles that stick tomucous-producing cells lining the lungs. The RNA produced isspecifically designed to suppress the protein NS1. Without NS1,...Scientists detect probable genetic cause of some Parkinson's disease cases
...sorder that is caused by the degeneration of nerve cells in theportion of the brain that controls movement....se eachyear. The disease occurs when certain nerve cells die or becomeimpaired and can no longer produce dopamine, a brain signaling chemical(neurotransmitte...Computers to be used to find blueprint for new influenza drug
...milar to part of the protective coating around the cells in our throats that the flu virus first attacks wh... virus which attack cells, and atoms of the throat cells that are attacked. By using advanced software to model the way these atoms behave in highly complex ...Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
...s (DA neurons) generated from monkey embryonicstem cells and transplanted into areas of the brain where the...t, were recently applied to primate embryonic stem cells andresulted in the generation of large numbers of DA neurons. In theircurrent JCI study, Jun Takahas...New Technique for Tracking Gene Regulators
...d off the genes that establish the very identityof cells ?be they brain cells, liver, or blood ?as well as ...rminewhich genes are at work in different types of cells under differentconditions,?he said.Previous, individual experiments have identified about 100 places...Bound for destruction: Ubiquitination protects against improper Notch signaling
...an) have identified the means by whichunstimulated cells protect the Notch receptor from activation.Recent ...presents a neat solution to theproblem confronting cells of how to prevent molecular loose cannonsfrom fouling their precisely ordered workplans....Combination therapy boosts effectiveness of telomere-directed cancer cell death
...ell can divide.In contrast to normal cells, cancer cells divide continuously anduncontrollably. Scientists know that cancer cells produce an enzyme,called telomerase, which prevents telomeres from getting too short socells can kee...Inflammatory molecules released by pollen trigger allergies
...leased from pollen. These molecules bind to immune cells and cause them to launch a typical allergy-promoti...lock the production of a soluble protein by immune cells that normally inhibits allergic reactions. They went on to identify the compound in the pollen extra...GATA: a graphic alignment tool for comparative sequence analysis
...ell can divide.In contrast to normal cells, cancer cells divide continuously anduncontrollably. Scientists know that cancer cells produce an enzyme,called telomerase, which prevents telomeres from getting too short socells can kee...“Nano-scissors?laser shows precise surgical capability
...nervecells that carry nerve impulses away from the cells to muscles or toother cells.“This tool opens up a ...stems. This laserallows researchers to study nerve cells at their most basicevolutionary form, opening the door to other experiments on genetic andmolecular ...U-M scientist to talk about tissue engineering at AAAS
...ts have a pretty good handle on how to teach human cells to do tricks in a laboratory---things like getting soft cells from the mouth's lining to form bone. But in the real world, accomplishing such feats is more compl...Genome-wide mouse study yields link to human leukemia
...a pre-leukemic stage marked by rapidly expanding T cells and natural killer cells, both major components of...cancer by identifying and getting rid of defective cells before they have a chance to mature and divide. When tumor suppressor genes lose that ability ?as th...Breakthrough Microarray-based Technology for the Study of Cancer
... to changes in the number of gene copiespresent in cells are important events in the genesis and progression ofcancer," said Michael Bittner of the Translational Genomics ResearchInstitute. "Agilent has now taken array-CGH experiments into a newrealm of resolution, sensitivity, and reproducibility that all...Iron Deficiency Sparks Dramatic Changes In Gene Expression
...spinach, seeds andother foods.Their study in yeast cells demonstrated that iron-starved cellspreserve the l...ized symptom is anemia, in which too few red blood cells areproduced, and the body is deprived of oxygen needed for energymetabolism. Iron deficiency causes ...Novel Enzyme Shows Potential As An Anti-HIV Target
...1’s catalytic center is removed. Experiments using cells taken from transgenic mice lacking SIRT1 demonstra...effects in a dose-dependent manner, while treating cells with the small molecule HR73, a derivative of a molecule that inhibits the yeast version of the SIRT...NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis
...cking the virus' release, which could infect other cells in the brain. "There is no magic bullet in fighting viral infections in neurons," said NYU Biology Professor Carol Shoshkes Reiss, the study's senior author. "However, these findings show the redundancy of the immune system--when one response fails ...Study finds more than one-third of human genome regulated by RNA
...searchers are shutting off genes by deliveringinto cells artificial microRNA-like molecules called siRNAs. ... Learning moreabout how microRNAs operate in human cells should help scientists tounderstand how best to exploit siRNAs for treating disease....Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
... affect the photoreceptor layer or "light sensing" cells of the retina. Night blindness develops, usually in childhood, followed by loss of peripheral visual field, progressing over many years to tunnel vision and finally blindness. At Emory Eye Center retina specialists Thomas M. Aaberg, Sr. and Jiong Ya...NYU researchers simulate molecular biological clock
...searchers are shutting off genes by deliveringinto cells artificial microRNA-like molecules called siRNAs. ... Learning moreabout how microRNAs operate in human cells should help scientists tounderstand how best to exploit siRNAs for treating disease....Mitochondrial DNA mutations play significant role in prostate cancer
...gene in 260 prostate cancer tissue samplesor blood cells from patients with confirmed cancer who had underg.... They theninjected these modified prostate cancer cells into mice to assess theirtumor-forming ability. The prostate cancer cells with the mutant mtDNAsgene...