A gene's first 'kiss' sets off that affair known as puberty
... chemical messages. Inside the hypothalamus, nerve cells release GnRH in a 'round-the-clock,' pulsatile fashion. With each secretion, the pituitary gland is stimulated to secrete its own messengers, lutenizing hormone (LH) and follicle-stimulating hormone (FSH), directly into the circulation. In turn, thes...DNA Molecules Used To Assemble Nanoparticles
...e complexes can be specifically targeted to cancer cells and are small enough to enter a diseased cell, eit...ndrimers hit their targets, were admitted into the cells and gave off their signaling light. The self-assembled dendrimer clusters were shown to be well form...Bioartificial kidney under study at MCG
...ificial kidney containing billions of donor kidney cells will help intensive care patients with kidney fail... device for kidney failure adds billions of kidney cells that can perform many of these important kidney functions. Human proximal tubule cells are collected...Viral DNA sequence a possible trigger for breast cancer
...ast tumor virus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et...l Medicine. The ability of this motif to transform cells single-handedly suggests that viral infection may be an important and previously unrecognized trigge...Wisconsin scientists grow critical nerve cells
...error, scientists have coaxed human embryonic stem cells to become spinal motor neurons, critical nervous s..., also known as Lou Gehrig's disease. With healthy cells grown in the lab, scientists could, in theory, replace dying motor neurons to restore function and a...Man and mouse share genome structures
... learn how the genome is translated to make living cells and organisms, and how we can use that information...ital and Harvard Medical School. "Every one of our cells has the same genome, yet is completely different. Muscle cells are different from neurons. They are ...Jump-starting T Cells In Skin Cancer
...e vaccines work by increasing the number of immune cells called killer T cells that can attack the tumor. In an unexpected finding, however, they discovered that that these cells ...Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...by a biochemical switch, or co-activator, in liver cells called PGC-1beta. Until now, scientists lacked a ... Spiegelman, who carries out basic research on fat cells and metabolic pathways in diabetes and cancer at Dana-Farber. "It offers the opportunity to try to u...A new mechanism of regulating RNA degradation
...ans who want to take control of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for players in this game is to recogniz...FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
...ans who want to take control of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for players in this game is to recogniz...Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. DNA repair is the system of defenses designed to protect the integrity ...Spleen may be source of versatile stem cells
...ed that the spleen might be a source of adult stem cells that could regenerate the insulin-producing islets...me team now report that these potential adult stem cells produce aprotein previously believed to be present only during the embryonicdevelopment of mammals.T...Researchers discover way to make cells in the eye sensitive to light
...chers have discovered a way to makelight sensitive cells in the eye by switching on a single gene.According...rs believethat by activating the melanopsin, these cells may gain the ability tosense and respond to light.Professor Mark Hankins, from Imperial College Lond...Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
...ntial use of Quantum Dots in live imaging of plant cells andprovides valuable understanding of the mechanism of interaction betweenthe pollen tube and female tissue during reproduction.“Integrating materials science, chemistry and plant biology tounderstand how and where specific proteins act on a pollen t...Source of molecular triggers in cutaneous T cell lymphoma identified
...rs that stimulate Cutaneous T Cell Lymphoma (CTCL) cells to clonally expand into large populations of malig...adult malignancy of T lymphocytes, the white blood cells of the immune system. Finding CTCL triggering factors has been a major goal of Richard L. Edelson, M...University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
...ild a fragment which will fit exactly. Wecan place cells in any designed position in order to grow tissue o...ssible.The reason for this is the way in which the cells are inserted into thestructures.Before being fed into the printer, the cells are suspended in anutri...Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
...lar potential to cause lasting damage to mammalian cells becausephotolyases ?a class of enzymes capable of efficiently repairing theselesions ?have apparently been lost from placental mammals over thecourse of evolution.Thus, most mammals, including humans, can only repair these lesionsthrough a much less ...It's not all genetic: Common epigenetic problem doubles cancer risk in mice
...tein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling t...h factor 2 (IGF2) develop more so-called precursor cells within the lining of the colon than normal mice. When these mice also carried a colon-cancer-causing...Columbia research lifts major hurdle to gene therapy for cancer
...ne therapy for cancer: its tendency to kill normal cells in theprocess of eradicating cancer cells.In a new...esignedvirus. The virus eradicated prostate cancer cells in the lab and inanimals while leaving normal cells unscathed. Genetherapy based on the new techniq......stem. They found that shigella was able to infect cells by using a secretion system to inject proteins int... inject proteins into human cells. This causes the cells to become inflamed, resulting in symptoms of dysentery, such as bloody diarrhoea. At the same time, ...