Tag: "cell" at biology news

Scientists learn the origin of rogue B cells

..."What happens is that, if the body ever produces a cell with a self-reactive antibody molecule, that cell will get arrested in development at the point where it is actually combining and creating an antibod...

Bacterial walls come tumbling down

...rning up bona fide drug targets has been slow. The cell wall enzymes in particular have tantalized scientists, Strynadka said. "The cell wall has all the hallmarks of a great drug target," she explained. "It is essential to the survival ...

Hybrid molecule causes cancer cells to self-destruct

...c bacteria that feed on fiber, can restore healthy cell functioning. Efforts to use butyrate as a gene...molecules more easily penetrate the surface of the cell than the individual chemicals. Once the components are inside, the researchers believe the partners ...

Soft-cell approach cuts animal tests

...r as little as one hour's exposure, they can study cell growth and metabolism, and a range of routine toxi...h as the amount of a contaminant needed to inhibit cell growth, mirror well-established lethal values obtained from animal studies - a long-established meth...

Columbia scientists determine 3-dimensional structure of cell's 'fuel gauge'

... of energy in the cell. When the energy level of a cell is high, meaning that the cell contains high amounts of an energy-carrying molecule known as ATP, AMPK directs cells toward "anabol...

3 proteins may play important role in nerve-cell repair

...urvival, and the regeneration of long parts of the cell called axons that carry the nerve impulses. Levels of cAMP drop in mammalian nerve cells as they mature, and this is thought to explain, in part, why mature nerve cells cannot regenerate damaged axons. "Our findings provide additional evidenc...

McBride shows DNA detective work with paper-eating bacteria that 'glide'

...tion of cellulose and chitin may also be linked to cell movement, or motility. "Loss of motility results...all directions around the cell's perimeter. "The cell wall appears to have a series of moving conveyer belts," he says. He also has learned that some of...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...site on March 11, 2007. To determine whether stem cell biology might play a role in benefiting degenerati...some conditions, eclipsed by a range of other stem cell actions that nevertheless exert a number of critical stabilizing forces," said Dr. Snyder, director ...

Synthetic peptide targets latent papilloma virus infections

...rom hitching a ride on a cell's chromosomes as the cell divides. If such a peptide - or more likely, a dru..." said Michael Botchan, professor of molecular and cell biology and a faculty affiliate of the UC Berkeley branch of the California Institute for Quantitati...

Bisexual fruit flies show new role for neurochemical

... receptors on nerve cells. The more receptors each cell has at its communication points, or synapses, the better that messages are carried through the brain. A UIC research team led by David Featherstone, assistant professor of biological sciences, has discovered that receptor numbers are controlled by ...

Anti-wrinkle compound causes pathological reaction in skin cells

...E induces a quick and spectacular swelling of skin cell vacuoles called fibroblasts, which act as reservoi... researchers observed an important slowing down of cell division—sometimes coming to a complete stop, the inhibition of certain metabolic reactions, and the...

Researchers find gene mutation that causes infertility in male mice

... combine during conception and create an embryonic cell with two chromosome sets, one from each parent. The mutation leads to a change in an amino acid in Dmc1 that blocks meiosis in its tracks, preventing sperm production. The mutant allele (one version of the pair of genes we inherit from each parent)...

A new study of living cells could revolutionize the way we test drugs

...p closer to both seeing the ‘heartbeat?of a living cell and a new way to test drugs. To stay alive, indi...ically charged particles, called ions across their cell membranes. This flow produces an electrical current that could, in principle, be detected with sensi...

Cold sore virus might play role in Alzheimer's disease

...ally flaring up in a "lytic" phase where it causes cell damage, then retreating and seeking safe harbor wi... study the team looking at the role of Nectin-1, a cell adhesion molecule that herpes uses as one route to infect a cell. Nectin-1 plays a crucial role in f...

Cancer-killing invention also harvests stem cells

...ion works. Finally, he learned that when a cancer cell breaks free of a primary tumor and enters circulat...form secondary, cancerous growths. As a cancer cell flows along the implanted surface, King's device captures it and delivers an apoptosis signal, a bio...

Chemo combination improves survival in asbestos-related cancer

...g-related death. Other side effects included blood cell abnormalities, nausea and diarrhea, which decreased in both incidence and severity after the vitamins were added to the treatment. People who work trades such as shipbuilding, railway engineering, construction work and asbestos manufacture have highe...

Bacteria control how infectious they become, study finds

...ocess of transferring genetic information inside a cell and one of the first steps of gene expression. “Making RfaH work only at specific sites is, in a sense, a genius way to prevent it from interfering with NusG,?Artsimovitch said. “It seems that the only genes that RfaH can't regulate are those cont...

Antifungal drug kills TB bug

...of its P450s that is essential for maintaining the cell structure," said Professor Munro. "We were able to show in laboratory experiments that various types of these azole drugs were also very good at killing the TB bacterium, and also that they bind very tightly to a number of the TB P450 enzymes that we...

Liver regeneration may be simpler than previously thought

...an increase in cells that multiply through regular cell divisions, a process called hyperplasia. The new results may also have important medical implications. Transcription factors are known to be more difficult to manipulate than the other identified proteins. Since the transcription factors were not...

New protein inhibitor impedes growth of cancerous cells

...f a protein that plays key roles in the control of cell division, and they show that the inhibitor can hal...n part by impeding multiple functions required for cell division and survival. One particular class of proteins, known as kinases, is known to play especial...

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