Researchers develop promising new gene network analysis method
...ene activity does it set off? The protein, c-Myc, causes cells to multiply. If the protein is produced unchecked, it can cause breast, colon and other types of cancer. C-Myc contributes to more than 70,000 deaths in the United States each year. Once the c-Myc switch is thrown, thousands of other genes sta...Diabetic nerve therapy shows 'striking' results
...n people worldwide could be affected by 2025. The causes of diabetic neuropathy are not fully understood but researchers investigating the effect of glucose on nerves believe it is likely to be a combination of factors. Sangamo's Chief Medical Officer, Dr Dale Ando, said: "We have been greatly encouraged ...Study Finds Moderate Hypothermia A Safe Treatment For Traumatic Brain Injury In Kids
...nal Institutes of Health. "Traumatic brain injury causes more children's deaths in this country than all other causes of death combined," said Dr. Adelson, who is the director of the Pediatric Neurotrauma Center at Chi...Specialized immune-system B cells play double-barreled role
... with Streptococcus pneumoniae, the bacterium that causes pneumonia. They found that the mice lacking B-1a cells were susceptible to infection, showing they lacked the natural antibodies of the innate immune system. Yet, these mice could be protected by immunization, which activated their adaptive long-term...One hit of crystal meth causes birth defects
... also try to determine whether the methamphetamine causes other lasting damage in mice, such as impacts on learning and memory. "Methamphetamine has very different toxic effects in the fetal brain than in adult mice, which surprised me," says Wells. "In adults, you can see actual structural degeneration of...Researchers discover mechanism for multiplying adult stem cells
...Still, the most provocative finding was that "Oct4 causes tumors by preventing adult stem cells in these tis...ue. In a mammal's body, this type of cell behavior causes tumors. But under the right laboratory conditions, it could be a powerful tool. "This may allow you...Scientists reveal how disease bacterium survives inside immune system cell
...lasma phagocytophilum, a tick-borne bacterium that causes granulocytic anaplasmosis in people, dogs, horses ... Minnesota and along the East Coast. HGA typically causes mild symptoms that include fever, muscle aches and nausea. Some 362 U.S. cases were reported to the ...Genetic links could unlock clues to leading cause of blindness
..., will allow researchers to delve deeper into what causes the disease and could be the first step toward rep... develop it within the next 15 years. The disease causes nodule-like specks to build up in the eye, chipping away central vision over time. But Dawson said m......s and signaling pathway of a Wnt-related gene that causes severe joint degenerative disease in humans. "More specific analyses such as gain-of-function and loss-of-function study of Wnt-7b will give us a clue which Wnt-7b would be an important pathobiological factor in rheumatoid arthritis," added Nakamura...Achilles heel of the herpes virus possibly found
...f the most common viruses in America, and one that causes the most guilt and shame. It can get inside almost any kind of human cell, reproduce in vast numbers, and linger for years in the body, causing everything from recurrent genital blisters to sores around the mouth. Its complications can kill, and it m...Scientists discover the body's marijuana-like compounds are crucial for stress-induced pain relief
...as the periaqueductal gray. In this region, stress causes the release of the naturally occurring marijuana-like compounds in the brain. A drug derived from the new research would likely be more effective and specific than smoked marijuana, said Hohmann. ...Scripps research scientists solve structure of a critical innate immune system protein
...ia like Neisseria meningitides--one of the leading causes of bacterial meningitis. TLR9 recognizes bacterial DNA that contains distinguishing CpG dinucleotides motifs . TLR3 in Detail Likewise, TLR3 recognizes double-stranded RNA, which is the form of genetic information carried by many viruses. The struc...International Team Determines Geographic Origin of Leprosy
...tic variations among strains of the bacterium that causes leprosy, included Patrick J. Brennan, Ph.D., of Co...terial of Mycobacterium leprae, the bacterium that causes leprosy, for tiny variations known as single nucleotide polymorphisms (SNPs). SNPs, pronounced "snip...New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
...thy tissues. Although it is not clear exactly what causes the immune system to go awry, there is increasing evidence that in some cases infections with viruses or bacteria may play a role. Now, a new study published in the June issue of Immunity provides evidence that bacterial infections induce a kind of s...Study: Harmless virus kills some cancers
...estigate the precise mechanisms through which AAV2 causes cancer cell death, and how the virus might be enhanced to more aggressively target and kill cancers. A provisional patent application for this work was recently submitted. ...A virus-like hitchhiker may trigger bacterial meningitis
...ely to have caused disease. How this bacteriophage causes N. meningitidis to become more dangerous is unknown. It may help the bacteria get into the bloodstream, suggests Tinsley, either by altering the bacteria or by disrupting the immune response that normally protects against it. ...Novel plague virulence factor identified
...e virulence of Yersinia pestis, the bacterium that causes plague. They also showed that the interaction between Y. pestis and the worm is quite similar to what occurs in mammals, including humans. The work indicates that the pathogen may use similar virulence mechanisms to infect evolutionary disperse organ...New Look at DNA Hints at Origin of UV Damage
...e virulence of Yersinia pestis, the bacterium that causes plague. They also showed that the interaction between Y. pestis and the worm is quite similar to what occurs in mammals, including humans. The work indicates that the pathogen may use similar virulence mechanisms to infect evolutionary disperse organ...Assessing the Amazon River's sensitivity to deforestation
...standing how the Amazon River varies in time, what causes those variations, and how sensitive it will be to ...land use change, researchers are investigating the causes of changes to stream hydrology and biogeochemistry. The Amazon, one of the most important watershed...Drug Offers Alternative to Surgical Treatment After Miscarriage
... women. Dr. Zhang noted that, because misoprostol causes uterine contractions, treatment with the drug could bring about abdominal pain and cramping. The researchers treated minor pain caused by the treatment with ibuprofen and treated more intense pain with codeine. He added that the misoprostol treatmen...