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Tag: "causes" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...ost vexing questions about human development: What causes puberty to begin? How is it that the full repertoire of reproductive hormones can exist at birth, go into hiding at about four to six months of age, then reemerge in full force some 10 to 12 years later? "Puberty is critical to human development. An...

Association of herpesvirus with lung disorder questioned

...ientists with another perspective on the potential causes of primary pulmonary hypertension," Dr. Katano said. "Further studies are required to clarify the possible association of human herpesvirus 8 with this disease." ...

Jump-starting T Cells In Skin Cancer

...yet these cells are unable to kill the tumor. What causes the impotence of these T cells is a mystery. Equal...cination against tumor-specific proteins sometimes causes tumor regression without expanding large numbers of vaccine-specific killer T cells. Pierre Coulie'...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, report that the harmful effects of saturated and trans fats ...

Dysentery uses 'sword and shield' to cause infection

Scientists have found that the bacterium that causes dysentery uses a 'sword and shield' approach to ca...ur, Paris, found that shigella, the bacteria which causes dysentery, is able to invade cells, while stopping any response from the immune system. They found ...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...cles ofthe legs, especially during exercise, which causes pain, aching,cramping or fatigue in the muscles of their legs when they walk. Thiscondition also is called " intermittent claudication ".The Emory team, led by cardiologist Arshed A. Quyyumi, MD, andcardiology fellow Veerappan Subramaniyam, MD, is us...

Fox Chase Cancer Center scientists identify immune-system mutation

... CD4 T cells is the primary mechanism by which HIV causes AIDS," Kappes said. The helper-deficient mice his team discovered represent the second time that a naturally occurring mutant strain has been found and bred at Fox Chase. In 1981, the laboratory group of Melvin Bosma, Ph.D., discovered mice with sev...

Neuronal 'traffic jam' marks early Alzheimer's disease

...recipitated by a "traffic jam" within neurons that causes swelling and prevents proper transport of proteins and structures in the cells, according to new studies by Howard Hughes Medical Institute researchers. In mouse models of Alzheimer's disease and in human brain samples from people with the disease, ...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...utations. One, utilized byscientists at Eli Lilly, causes amyloid plaques to build up, creatingthe Alzheimer..., developed by scientists atWashington University, causes some of the mouse brain cells to producea dye that allowed Brendza to obtain detailed images of nerv...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...arasite infects an estimated 50 million people and causes as many as 100,000 deaths a year -- second only to... The disease can cause liver damage but more often causes dysentery, a severe diarrhea that is often associated with blood in the feces. Unchecked, the diarrh...

Key molecule in plant photo-protection identified

...utations. One, utilized byscientists at Eli Lilly, causes amyloid plaques to build up, creatingthe Alzheimer..., developed by scientists atWashington University, causes some of the mouse brain cells to producea dye that allowed Brendza to obtain detailed images of nerv...

Timing is everything: First step in protein building revealed

... expression, and gene expressionkeeps us alive and causes disease," says Lorsch. "If we can betterunderstand how the ribosome works, perhaps we can harness it to help usfix disease."Already, scientists knew that without eIF1, the ribosome can startreading the gene's RNA instructions at places other than a p...

Research advances quest for HIV-1 vaccine

...guide design of vaccines for HIV-1, the virus that causes AIDS. A new detailed structural analysis of the complex formed by an anti-HIV antibody called 4E10 and its specific target provides insight into why this particular antibody is so broadly effective, a rare characteristic for HIV discovered thus far. ...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...s of individual genemeasurements to help determine causes of variability, and they foundthat laboratory practices comprised the smallest source of variation inthese studies. Measurement errors common to all labs were the next mostcommon contributor, and biological differences in different sampleswere the la...

Scientists detect probable genetic cause of some Parkinson's disease cases

...ease that are genetic in origin,this gene mutation causes more cases of Parkinson's disease than anyother gene discovered to date," says Andrew Singleton, Ph.D., chief ofthe Molecular Genetics Unit in the NIA's Laboratory of Neurogenetics."Knowing that this mutation is not only important in familial forms o...

Research on Worms Yields Clues on Aging

...mans. "We didn'tstart with a hypothesis about what causes aging," says senior authorKerry Kornfeld, M.D., Ph.D., associate professor of molecular biologyand pharmacology. "We wanted to look in an unbiased way at availablecompounds to see if any of them happened to have anti-aging activity."The researchers g...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...xygen needed for energymetabolism. Iron deficiency causes wide-ranging symptoms from fatigue,weakness and cognitive deficits to serious heart complications anddevelopmental disorders. Iron deficiency also contributes to thepathology of hereditary blood disorders, Parkinson's disease andcertain cancers and d...

Learning to fight an adversary that won't stay down

...d Staphylococcus aureus (MRSA), the bacterium that causes methicillin-resistant tuberculosis, provide good examples of the challenges we face, says Dr. Davies. Ironically, he says, advances in molecular biology techniques have shown just how adept these pathogens are at adapting to anything we can throw at...

U of M researcher examines newly emerging deadly disease

...ases of purpura fulminans to better understand the causes and best treatment options." On the basis of experience, the University of Minnesota experts have identified three recommended treatments for purpura fulminans. Patients who present symptoms of purpura should receive antibiotic therapy not only agai...

Live Recombinant Adenovirus Vaccine Technique Explored

...V) that could be used in the developing world. HPV causes 500,000 cases of cervical cancer each year worldwide. Recombinant HPV vaccines currently in clinical trials may not be ideal in poorer countries because they are expensive and require multiple immunizations. The Hopkins researchers developed their v...

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