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Tag: "cause" at biology news

Silence the gene, save the cell: RNA interference as promising therapy for ALS

...ad author Cedric Raoul and colleagues targeted the cause of the disease by using RNA interference to silence the defective gene, preventing it from expressing the SOD1 protein. RNA interference is part of a complex cellular housekeeping process that protects cells from invading viruses or other genetic th...

Researchers report new pro-inflammatory role for anti-inflammatory enzyme

...be a bad thing. Sustained overproduction of NO can cause septic shock (sepsis). "In sepsis, which is a systemic bacterial infection, the body expresses iNOS which generates relatively high concentrations of NO," says Dr. Hobbs. "This aids host defense by killing the invading organism, but in excessive quan...

Discovery may lead to better Candidiasis drug

...n. "In addition, many other pathogenic fungi that cause disease in elderly individuals or AIDS patients also should be able to be killed by histatins or drugs designed to target their potassium channels." ...

NASA study finds snow melt causes large ocean plant blooms

...mber. In the Western Arabian Sea, these winds also cause upwelling of cooler nutrient-rich water, creating ...cess. An increase in phytoplankton could therefore cause oxygen deficiencies in the Arabian Sea to spread, leading to fish mortality. Oxygen-depleted waters...

Small species back-up giant marsupial climate change extinction claim

...Science who led the study, says: "Unravelling the cause of the late Ice Age extinction has occupied scientists for centuries. It is essential to know if the risks faced by species and ecosystems today are the same as those in the past. "If we can document past environmental change and its influence on th...

New Estimates For The Causes Of Child Deaths Worldwide

...0 to 2003 to obtain new estimates for mortality by cause in children younger than age 5 years. They found t...29% of all deaths. Undernutrition is an underlying cause of 53% of all deaths in children aged younger than 5 years. The investigators also calculated the to...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

... disorder with small vessel disease, a significant cause of lacunar or "mini" strokes that can damage small...or coordination. Multiple lacunar strokes can also cause cognitive and memory deficits that resemble Alzheimer's disease. According to the authors, physicia...

Emergence of cancer as major cause of childhood death in developing countries is not being adequately addressed

The emergence of cancer as a major cause of death among children in developing regions of the world is not being adequately addressed by national or international health organizations and charities, according to investigators at St. Jude Children’s Research Hospital. This growing rate of pe...

Same-Sex Mating Discovered in a Toxic Fungus

.... neoformans invades the central nervous system to cause disease, most commonly in immune-compromised patie...itman said, "the more we know about the biological cause of any disease, the better positioned we are to develop cost-effective diagnostic or therapeutic int...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

...ls are large. When the egg is thawed, ice crystals cause damage that prevents the egg from being fertilized...nts such as chemotherapy and radiation therapy can cause damage to a woman's reproductive system and leave her unable to have children afterward. Some women ...

Youth With HIV Take More Risks After New Meds Introduced

...es not prove that the introduction of HAART is the cause of increased risky behavior, "these findings indicate the need for continued attention to the issue of sexual risk and the impact of HAART," Lightfoot says. The new study also suggests the lives of some HIV-positive teens have not improved with HAAR...

Nano-bumps could help repair clogged blood vessels

...we've been trying to do is find new materials that cause the endothelial cells to attach better to these stents without creating as much dangerous scar tissue." The researchers tested discs of titanium containing surface bumps about as wide as 100 nanometers ?or billionths of a meter. The metals used to m...

UNC launches study of liver injury caused by drugs

...ers. Drug-induced liver injury is the most common cause of sudden liver failure nationwide and the most co... at UNC. "This is the case even though drugs that cause liver injury are usually entirely safe for the majority of patients taking them," he added. The main...

Leprosy microbes lead scientists to immune discovery

...an spread along nerves throughout the body and may cause blindness. The scientists found DC-SIGN+ macrophages in both types of leprosy infections. The CD1b+ cells were present only in the milder form, indicating a successful battle against the leprosy bacterium. They were missing, however, in the more sev...

Bioelectronic ‘signatures?hold key to DNA mutations

...human genome. Not every SNP found will necessarily cause a mutation or determine our eye or hair color ?but...ing a single nanocrystal ?bind to a DNA sample and cause minute electrical current changes in the nanocrystal that can be measured with an electrode. The ind...

New understanding of DNA repair may pave way to cancer treatments

...owing ionizing irradiation or other exposures that cause breaks in DNA. A likely way in which ATF2 works is to halt the cell's cycle to allow repair of damaged DNA before such damage becomes permanent." Ronai and his colleagues are now determining how molecules like ATF2 can balance their dual roles. "Hig...

Live vaccines more effective against horse herpes virus

...e and fatigue for a day or two. The virus can also cause pregnant mares to abort, and in its severest form it can lead to neurological disorders, loss of coordination and even death. The virus is spread mainly by intimate contact between horses. Once infected, a horse carries the virus for the rest of its ...

Duke engineers develop new 3-D cardiac imaging probe

...s ablation probes that burn off damaged cells that cause an irregular heart beat. Clinicians must repeatedly and painstakingly reposition the 2-D probe during treatments so, instead, they use fluoroscopy (X-ray movies) to guide the placement of the treatment devices. However, the use of X-ray imaging resul...

New tumor-suppressor gene discovered

...cate that the disabling of this one gene alone can cause the growth of tumors. The researchers then did a number of experiments to study this line of flies with the clearly defective mats gene. "With transgenic techniques, we were able to introduce a normal mats gene into the chromosomes of flies whose ma...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...ed, aberrant expression of genes is the underlying cause of many different diseases. For example, the expr...must be finely tuned so that these proteins do not cause more damage to the body than the bacterial infection they were produced to defeat. Excessive inflamm...

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