Substance protects resilient staph bacteria
...pidermidis strain deficient of PGA was not able to cause infection while the other strains containing PGA did. ......ase CAPERá and CAPERâ. These coactivators not only cause the gene to begin the process that results in protein production, they also determine what kind of RNA (a kind of genetic template for the protein) is made as well as what kind of protein results. "This subgroup of coactivators, when brought to the ......s is harmless on human skin, but it is the leading cause of hospital-acquired infections and infections of indwelling medical devices. S. epidermidis is associated with an enormous number of infections in people with prosthetic joints, replacement heart valves, and intravenous catheters, and antibiotic res...Discovery Promises Simpler Therapy for Sickle Cell Disease
... red cells from those with severe disease symptoms cause blood vessels to constrict when oxygen levels drop, they found, a response which would further exacerbate the oxygen deficiency. Treatment of red blood cells with nitric oxide reversed that effect, they reported. "Our results suggest that abnormal b...Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries
...ophages produce pro-inflammatory substances, which cause a secondary effect, encouraging other cells to acc... to a number of cardiovascular diseases ?the No. 1 cause of death among people in the United States. It is also highly associated with other risk factors suc...Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks
...led “precardiac endoderm?sends strong signals that cause adjacent cells in the embryo to become cardiac myocytes. Based on this finding, Dr. Lough reasoned that precardiac endoderm might similarly induce ES cells to become a homogeneous population of cardiac myocytes. Working with Diane Rudy-Reil, Ph.D., ...Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection
...te into fibrous tangles called amyloid fibrils and cause fatal wasting of brain tissue. The abnormally folded protein itself appears to act as an infectious agent, transmitting disease without a DNA or RNA genome such as in a virus. Although disease prions seem to infect normal prions by binding to them an...WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas
...s to multiply to sufficient levels, to potentially cause severe public health problems. Most affected coun...ions without proper shelter. Different mosquitoes cause different vector-borne diseases. Dengue fever is carried by the Aedes aegypti mosquito (a day-time b...Single stem cells from bone heal a broken heart
...sults in irreversible damage to the heart that can cause congestive heart failure. The lasting damage results from the limited ability of the myocardium to regenerate and self-repair. Douglas Losordo and colleagues from Tufts University now document the existence of a previously unrecognized subset of huma...Light therapy may combat fungal infections, new evidence suggests
.... neoformans invades the central nervous system to cause disease, most commonly in patients who lack a functioning immune system, such as organ transplant recipients, those with HIV/AIDS, and patients treated with steroids or cancer chemotherapy. The fungus' global importance as a health threat has therefo...New lab technique identifies high levels of pathogens in therapy pool
...microbes included "Mycobacterium avium," which can cause "lifeguard lung" and which was present in nine ill lifeguards who worked at the facility. The technique used in the study is 1,000 times more sensitive than standard microbe-culturing techniques used at most indoor pool facilities today, the researc...Nanoparticles offer new hope for detection and treatment
...h of an inch) wide. Small, rapidly growing tumors cause growth of new blood vessels, which feed the tumors. To get the particles to bind to tumors, the researchers equipped them with tiny "hooks" that link only to complementary "loops" found on cells in newly forming blood vessels. When the nanoparticles ...Buying Time Through Hibernation on Demand
...l time it takes to diagnose the bacterial or viral cause and administer the proper antibiotic. "Here's a patient group, quite commonly found in emergency rooms around the country, who would do well if they could just have their core body temperature taken down in order to buy them time until the pathology...U-M team recovers ancient whale in Egyptian desert
...l time it takes to diagnose the bacterial or viral cause and administer the proper antibiotic. "Here's a patient group, quite commonly found in emergency rooms around the country, who would do well if they could just have their core body temperature taken down in order to buy them time until the pathology...Chemicals in tattoo inks need closer scrutiny
...ere have been a variety of claims that tattoo inks cause adverse effects in people, including allergic reactions to ink components, a burning sensation during the course of MRIs, and the migration of inks to different tissues in the body, such as the lungs. It is unclear, however, what the specific causes...Strongest proof yet found for prion hypothesis
...st evidence yet that infectious misformed proteins cause mad cow disease and other mysterious brain disorders Researchers at the University of Texas Medical Branch at Galveston (UTMB) have produced the strongest proof yet that the mysterious and devastating brain diseases known as "transmissible spongifor...Researchers uncover sequence of major rice pathogen
...ure. It is estimated that rice blast, the leading cause of rice loss, is responsible each year for killing...e light on the adaptations required by a fungus to cause disease. The researchers identify novel receptors that allow the fungus to recognize its environment...To control germs, scientists deploy tiny agents provocateurs
...n-inducing layers on implanted medical devices and cause deadly lung infections in cystic fibrosis patients. Biofilms have long baffled researchers because of their stupefying capacity to behave like a "super-organism" that vetoes the normal characteristics of a bacterial cell in favor of new group behavio...Disease diagnosis, biodefense among UH chemical research projects
... research is important because infectious diseases cause 26 percent of global mortality and are the third leading cause of death in the United States. Microbial identification also is important in food safety and biodefe......ndergoing chemotherapy and radiotherapy, which can cause infertility and premature menopause," says Dr. Lucy Gilbert, Director of Gynecological Oncology at the MUHC. Over the past two years, 16 cancer patients have had their eggs frozen at the MUHC. "Egg freezing also allows young women who wish to delay c...