Gene therapy converts dead bone graft to new, living tissue
...en the bone wears over time. "Everyday activities cause microscopic fractures in our bones," explains Schwarz. "Those fractures are normal and healthy, and our bones re-knit them constantly. But when the bone is dead, there is no healing, and those tiny fractures begin to accumulate until finally, perhaps...Researchers reveal the infectious impact of salmon farms on wild salmon
...g strategy. The field study also discovered a new cause for alarm: once the young salmon pass the farm and pick up the sea lice, the migrating school becomes a moving cloud of contagions. Sea lice larvae mature and reproduce on the seaward salmon with each louse producing 300-800 eggs. This second round o...Molecular machine may lead to new drugs to combat human diseases
...sites at which they bind with various molecules to cause biochemical reactions. Scientists can use this kno...alth, Group I introns are interesting because they cause their own removal and also splice the ends of the surrounding RNA together, forming a functional gen...Color-blind method opens new doors in DNA sequencing
...een the dyes results in subtle variations that can cause nucleotides to be miscalled. The new method developed at BCM and Rice, called pulsed multiline excitation, uses four lasers, each matched to a particular dye. PME enables the researchers to take advantage of the entire visible spectrum, eliminating ...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...erations in neural development are thought to be a cause ofautism," says Jill Kreiling, first author of the paper and a member ofReinisch's lab. But Kreiling cautions, "We cannot say at this time ifthe alteration we see in clam embryos is the same alteration thatcauses autism. That will require future rese...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...erations in neural development are thought to be a cause ofautism," says Jill Kreiling, first author of the paper and a member ofReinisch's lab. But Kreiling cautions, "We cannot say at this time ifthe alteration we see in clam embryos is the same alteration thatcauses autism. That will require future rese...A bacterial genome reveals new targets to combat infectious disease
... infection with filarial nematodes, parasites that cause elephantiasis, African river blindness, and other debilitating diseases in more than 150 million people worldwide. The nematodes themselves play host to bacteria that live within their cells, but in this case, the relationship is classic mutualism, w...BRCA1 causes ovarian cancer through indirect, biochemical route
Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the Univer...Scientists decipher genome of fungus that can cause life-threatening infections
...mostcommon opportunistic infections, and a leading cause of meningitis andbloodstream infection," says Joseph Heitman, a senior communitycollaborator on the project who is James B. Duke Professor of MolecularGenetics and Microbiology at the Duke University Medical Center and aninvestigator at the Howard Hu...Needling Chromosomes Reveals Cell Division Secret
...an lead to cancer or chromosomal abnormalitiesthat cause birthdefects."According to Nicklas, it was known that the two sister chromatidsadhered to one another and released at the appropriate time during celldivision. However, that understanding was based on biochemicalexperiments that revealed when the "gl...Scientists discover the cellular roots of graying hair
... scientists have been unableto explain the precise cause of this usually unwelcome transformation.In a repo...’s HospitalBoston say they have found the cellular cause of graying hair whileinvestigating the origins of malignant melanoma, the potentially deadlyskin can...Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery
... scientists have been unableto explain the precise cause of this usually unwelcome transformation.In a repo...’s HospitalBoston say they have found the cellular cause of graying hair whileinvestigating the origins of malignant melanoma, the potentially deadlyskin can...... scientists have been unableto explain the precise cause of this usually unwelcome transformation.In a repo...’s HospitalBoston say they have found the cellular cause of graying hair whileinvestigating the origins of malignant melanoma, the potentially deadlyskin can...Experiments provide proof of how traveling in groups protects insects
... but in parts of Africa and elsewhere, locusts can cause widespread famine because they consume crops, and the people there sometimes have nothing else to eat." ...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
...r growth," Bernstein notes. "Some of the genes can cause cancer directly when altered by mutations." "The work we're doing now is very fundamental," he says. "But what we learn about the interactions between chromatin, its tags, and various proteins that interact with them may one day be useful for unders...U-M scientists find genes that control growth of common skin cancer
... spread or metastasize. However, untreatedBCCs can cause extensive local tissue damage, and surgical procedurescan produce significant scarring in cosmetically sensitive locations,such as the face.The Hedgehog signaling pathway plays a key role in normal development,and its dysfunction has been implicated ...Experiments provide proof of how traveling in groups protects insects
... but in parts of Africa and elsewhere, locusts can cause widespread famine because they consume crops, and the people there sometimes have nothing else to eat." ...Critical role in programmed cell death identified
... die. The researchers demonstrated that when they cause worm mitochondria to fragment without instructing cells to die, the cells still die and when they block fragmentation, the cells survive; in other words, blocking fragmentation prevents cell death, inducing fragmentation provokes cell death. "This p...Study: Soap And Water Work Best In Ridding Hands Of Disease Viruses
...at causes the common cold. Other removable viruses cause hepatitis A, acute gastroenteritis and a host of other illnesses. A separate key finding was that waterless handwipes only removed roughly 50 percent of bacteria from volunteer subjects?hands. "We studied the efficacy of 14 different hand hygiene a...