Gene silencing technique offers new strategy for treating, curing disease
...tated genes lead to malfunctioning proteins, which cause disease. The information in a gene is not directly converted into proteins, but first is copied by special enzymes into many copies of messenger RNA, which then move out of the nucleus and into the body of the cell, where they go on to create a prot...U of T researchers map role of Epstein-Barr virus in cancer
..." Frappier says. "All viruses known to be able to cause cancer, like the human papillomavirus that causes ...tter methods of combating viruses like these which cause disease, says Frappier. ...UCLA cancer researchers shake loose hidden biomarker
...n accessible area in the basolateral surface." To cause this disturbance and the resulting relocation of P...cted to die. Prostate cancer is the second leading cause of cancer death in men. ...Study of energy and health in Africa focuses spotlight on charcoal and forest management
... 2030, smoke from wood fires used for cooking will cause about 10 million premature deaths among women and children in Africa. By 2050, according to the report, smoke from cooking fires will release about 7 billion tons of carbon in the form of greenhouse gases to the environment. That's about 6 percent of...FDA Approves New Treatment for Chronic Hepatitis B
... virus (HBV) that attacks the liver. The virus can cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure, and death. According to the Centers for Disease Control and Prevention, approximately 1.25 million Americans are chronically infected with the HBV virus. Baraclude s...High-powered gene profiles provide clues to genes involved in common form of lung cancer
...r the basic biology of lung cancer, the number one cause of cancer-related deaths in the United States. Non-small cell lung cancer (NSCLC) accounts for about 75 percent of all lung cancers and is responsible for nearly 120,000 deaths in this country annually. It is one of the most difficult cancers to trea...Genome study of beneficial microbe may help boost plant health
... and seeds from infection by harmful microbes that cause plant diseases. The genome paper will be published in Nature Biotechnology and was scheduled to be posted online on June 26. "The genome sequence has helped us identify new chemical pathways that the microbe apparently uses to create what are known ...Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
...e University of Chicago show how the bacteria that cause the plague manage to outsmart the immune system and how, by slightly altering one of the microbe's tools, the researchers produced what may be the first safe and effective vaccine. Both papers -- one published online July 28 in Science Express and o...Immune system's distress signal tells bacteria when to strike back
... causing gut-derived sepsis. It is also a frequent cause of infections after major surgery. Physicians have theorized, said Alverdy, that germs such as Pseudomonas are always "probing for a weakness in the host and are ready and willing to strike whenever they find one." He and his colleagues, however, ar...Scientists discover global pattern of big fish diversity in open oceans
...e, it has been difficult to discern the underlying cause of decreases or increases of catch. This study is ...towards a reduction in biodiversity. There is real cause for alarm here." Scientists say losing the variety of fish does not bode well for the future health...Excess liver gene protects against high-fat diet
...otic cardiovascular disease, making it the leading cause of death in industrialized nations," said study senior author Mitchell Lazar, of the University of Pennsylvania School of Medicine. "Yet we know that some people are more susceptible than others to obesity and other problems of excess, suggesting tha...Two studies document rise of superbugs in the environment
...e drug-resistant "superbugs" can infect people and cause health problems that are difficult to address with...eported recently in the medical literature. It can cause problems ranging from skin infections to severe bloodstream infections and even death. Researchers ...Researchers make headway in mystery of migraines
...iences (PNAS), reveals how gene mutations known to cause a form of inherited migraine--the kind that cause debilitating headaches and light flashes known as auras--target a cellular process involved in brain...Combination therapy leads to partial recovery from spinal cord injury in rats
... anatomy -- to point clearly at myelination as the cause for improved function," says Naomi Kleitman, Ph.D., the NINDS program director for the grants that funded this work. "The study also is a good example of strong collaboration between two spinal cord injury research centers, one at the University of L...Scientists inhibit cancer gene
...called DGK iota, we thought that its absence would cause more tumors to develop, as has happened with other DGKs we have tested. This time, though, when we tested mice with an activated Ras gene, but an absent DGK iota gene, the number of tumors was significantly reduced," Topham says. "This result is inte...Mosaic mouse technique offers a powerful new tool to study diseases and genetics
...mutation) of a gene, the recombination event could cause an offspring to inherit two bad copies of the gene, which would result in a mutant cell. This process simultaneously activates the green fluorescent protein, which turns the mutant cell green. "If there is no recombination, there are neither green n...UNC plant researchers discover proteins interact to form hair-trigger protection against invaders
...k is important because every year, these organisms cause us to lose some 30 percent of our grain, fruit and vegetable crops after all the human, water and soil energy has already gone into producing them," Dangl said. "The hope is that we might be able to manipulate plants' immune systems to make them more...Researchers develop promising new gene network analysis method
...iply. If the protein is produced unchecked, it can cause breast, colon and other types of cancer. C-Myc contributes to more than 70,000 deaths in the United States each year. Once the c-Myc switch is thrown, thousands of other genes start pumping out proteins or switching on other genes, which activates s...FDA approves more generic AIDS drugs
...k is important because every year, these organisms cause us to lose some 30 percent of our grain, fruit and vegetable crops after all the human, water and soil energy has already gone into producing them," Dangl said. "The hope is that we might be able to manipulate plants' immune systems to make them more...... long-term. Nerve disease in diabetes is the major cause of non-traumatic lower limb amputations in Europe ... diabetes develop some form of neuropathy that can cause numbness and sometimes pain and weakness in the hands, arms, feet and legs. Currently, patients are...