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Tag: "carry" at biology news

Nano-particles effective in killing cancer with one-two punch of chemotherapeutics

... but there hasn't been any carrier system that can carry both drugs as efficiently to a tumor," said Fariyal Ahmed, the lead author, former doctoral student in bioengineering,and now a fellow at Harvard Medical School. "Polymersomes get around those limitations". Discher developed polymersomes with Pen...

A large step forward in the fight against African sleeping sickness

...rings the ApoL-1 variant to the place where it can carry out its neutralizing action. All the tests performed on mice have been very promising: Trypanosome-infected mice survive after 1 treatment. The parasite is removed from the blood and all effects associated with the disease disappear. There is every...

Biologists develop genome-wide map of miRNA-mRNA interactions

...arrying target 3' UTRs with controls, that did not carry the target 3'UTRs. The laboratory results confirmed the role of specific 3' UTRs in suppressing gene expression even more widely than predicted by the computational analysis, suggesting that 3' UTRs contain a largely unexplored universe for gene regu...

Berkeley researchers lay groundwork for cell version of DNA chip

...hem to assemble into different types of tissue, or carry out functions critical to an organism's health and well-being. Cell adhesion is now being used to incorporate biological cells into simple devices, but is expected to be important for the future production of complex nanotechnology devices. To date...

New test to detect rare proteins in blood

...apse. The Greene lab developed mouse models that carry cancer cells overexpressing Her2/neu. When these cells are implanted into animals they form tumors exactly like breast tumors in humans. Using ELISA, the researchers could not detect Her2/neu from mouse blood until the tumors reached an inoperable si...

Oops! Researchers publish new findings on the brain's response to costly mistakes

...he same level of activity when the mistake doesn't carry a penalty, or even when a correct action carries a reward. The rACC is thought to be involved with emotional responses, and scientists had suspected it might also be involved in response to costly errors. But this is the first brain-imaging study to ...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...diseases. On average, it costs about $3 million to carry out one study. "We've translated early information from genetic research into valuable medicines for HIV/AIDS, heart disease and the prevention of organ rejection," said Martin Mackay, Ph.D., Senior Vice President Worldwide Research & Technology...

Polymer aids in blood clotting, pointing way to new treatment

...he Center for Hemostasis Research at Illinois will carry the new discovery further. Morrissey and Illinois colleagues Stephen Sligar, a professor of biochemistry, and Lawrence B. Schook, a professor of animal sciences, will lead a variety of experiments. Among them, they will test the use of polyphosphate ...

Deep-rooted plants have much greater impact on climate than experts thought

...ribution during the dry season allows the plant to carry on photosynthesis at a higher rate, leading to greater carbon uptake. This also leads to greater evaporation from the leaves of water, which takes heat with it. Thus, the summer dry-season temperatures are cooler than would be expected. "When Jung-E...

Scientists reveal how deadly toxin hijacks cells

... acquired mice that were genetically engineered to carry reduced amounts of SV2. Without that protein around, the researchers found that botox was unable to wreak havoc. Co-author Felix Yeh, a UW-Madison graduate student who works with Chapman, says that researchers have so far found three of the seven pr...

U-M scientists identify major psoriasis susceptibility gene

... the immune system fights off infection. MHC genes carry DNA-coded instructions for proteins whose job it is to distinguish between what belongs in the body and what doesn't. "There is a great deal of genetic variation in the MHC, because it's on the front lines of dealing with pathogens and cancer," Elde...

Common enzyme is a key player in DNA repair

... make up the genes that code for the proteins that carry out the routine and complex tasks necessary for life. Now, researchers in Walker's lab have discovered that the enzyme DinB is exceptionally skilled at copying over a particular kind of damage to the G nucleotide. When the main DNA replication mach...

Alternatives to the use of nitrate as a fertiliser

...gated. The high concentration of ammonium does not carry oxidative stress with it (i.e. the molecules are oxidised due to alteration produced in the enzymes), unlike that which occurs in the majority of these states. The activation of some antioxidant enzymes is reflection of stress that ammonium produces ...

Study in Science holds promise for a new approach to drug therapy

...es, passing on messages that make vision possible, carry nerve messages, enable white blood cells to attack infection and set the timing of the heartbeat. Faulty GPCR signaling, on the other hand, plays a key role in several major diseases. As a result, GCPRs are targeted by 12 of the top 20 selling drugs,...

Researchers develop portable 'vein finder' for faster, more accurate injections

...ction of blood flow to distinguish arteries (which carry blood away from the heart) from veins (which carry blood to the heart). Once the device detects a vein, an alarm is triggered, and medics insert the ne...

Cheaper and simpler keyhole surgery

...ther hand, it is very difficult for the surgeon to carry out keyhole surgery. This is due to the disruption of hand-eye coordination, as the surgeon has to operate via a 2D image on a monitor. Moreover, the video camera has to be operated by an assistant and the work must be done using long and rigid instr...

Nanotechnology may find disease before it starts

...iscule size, nanoparticles are still big enough to carry a payload of medicine, Rosol said. "That the particles made it into the liver suggests that they could be used to deliver toxic chemotherapeutic drugs that would act locally on a tissue, at the site of a tumor, and not have such a pronounced affect ...

The closest look ever at the cell's machines

...ears in this week's online edition of Nature. "To carry out their tasks, most proteins work in dynamic complexes that may contain dozens of molecules," says Giulio Superti-Furga, who launched the large-scale project at Cellzome four years ago. "If you think of the cell as a factory floor, up to now, we've...

MIT: Oceans are a major gene swap-meet for plankton

...robes such as Prochlorococcus. Such viruses, which carry genes of their own and sometimes transport odd genes picked up from an earlier host, are the most likely means of exchange - a natural way to get genes out of old cells and into new ones. In essence, what all this means is that "our image of ocean m...

Infections could contribute to adult brain tumours

...e expected by chance. This is the first study to carry out this sophisticated form of statistical analysis known as 'clustering' in brain tumours in adults. The results of this work are consistent with earlier research led by Dr McNally into childhood cancer in North West England. This discovered pat...

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