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Tag: "cardiac" at biology news

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

...e. In addition, long-term toxic effects, including cardiac deaths, were acceptable for both groups of patients. "Our results, and those from other groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the add...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

...e. In addition, long-term toxic effects, including cardiac deaths, were acceptable for both groups of patients. "Our results, and those from other groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the add...

Timing is everything: First step in protein building revealed

..." And excessiveamounts of eIF1 are associated with cardiac hypertrophy, or an enlargedheart.While eIF1's role in cardiac hypertrophy remains a mystery, the newdiscovery reveals exactly how eIF1 regulates the ribosome's ac...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

..., including those closely tied to brain disorders, cardiac illness, and other major conditions. He pointed out that clathrin is also important to cellular mechanisms other than endocytosis, including those occurring deep inside the cell. "Now that we have a better handle on this relationship, we're going t...

Nanogen Issued Patent for Electronic Microarray With Memory

...care diagnostic tests and is building expertise in cardiac related health conditions. Nanogen's ten years of pioneering research involving nanotechnology may also have future applications in medical diagnostics, biowarfare and other industries. For additional information please visit Nanogen's website at www...

X-Ray Beams And Fruit Fly 'Flight Simulator' Aid Scientists' View Of Muscle Power

...artment of Energy’s Argonne National Laboratory, a cardiac molecular motors expert from the University of Ver...cle and other oscillatory muscles, including human cardiac muscle, mean that the research may be adaptable for other uses. “Both insect flight and human heart...

UCSD team discovers specialized, rare heart stem cells in newborns

The first evidence of cardiac progenitor cells ?rare, specialized stem cells loc...ly mature heart tissue. Called isl1+ cells, these cardiac progenitor cells are stem cells that have been programmed to form heart muscle during fetal growth. ...

Implanted Devices Detect High-Risk Heart Failure Patients

Implanted devices intended to optimize the cardiac function of patients with heart failure have provided new insights into which patients might be at higher risk of dying suddenly from their disease, according to researchers at Duke University Medical Center. Besides maintaining optimal electrical s...

Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments

...weeks following the procedure which is done in the cardiac catheterization lab at Rush," said Dr. Gary L. Sch...ssigned to receive the gene administered through a cardiac catheter threaded into the heart from a leg artery or a placebo delivered using the same method. As ...

Special Imaging Study Shows Failing Hearts Are 'Energy Starved'

... performed MRS on 14 healthy volunteers to measure cardiac CK flux at rest and with pharmaceutically induced stress to determine whether increased energy demand during stress increases the rate of ATP synthesis through CK. Then, 17 patients with histories of heart failure were similarly tested to measure t...

Supercomputer Dedicated To Bioengineering, Computational Biology Installed

... subcellular structures such as nerve synapses and cardiac muscle cells, to multicellular tissue and the whole heart. Bioengineering professor David Gough (left), principal investigator of NBCR Peter Arzberger, Bioengineering vice chair Andrew McCulloch, director of SDSC's Advanced CyberInfrastructure Lab P...

Effective Cancer Treatments Follow The Clock

...est and activity, fluid balance, body temperature, cardiac output, oxygen consumption and endocrine gland secretion. In their experiments, the researchers measured the animals' body weight as an indicator of response to the anti-cancer drug. They discovered that Clock-mutant and Bmal1-knockout mice showed h...

Use of PET can reduce, may eliminate more strenuous drug development trials with animals

... cancer therapies on tumor function and performing cardiac studies that explore drugs that reverse the conditions of animals. The JNM articles on small animal imaging, with numerous SNM members as authors, are listed here. * Welch's co-author of "Preparation, Biodistribution and Small Animal PET of 45T...

Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks

...eutic application. Dr. Lough’s research focuses on cardiac myocytes, which are found in the myocardium tissue...t has a heart attack, significant numbers of these cardiac myocytes die, and the damaged heart muscle is replaced by scar tissue that isn’t able to contract an...

Single stem cells from bone heal a broken heart

... rat model of myocardial infarction. This improved cardiac function because the cells stimulated release of growth factors and anti-apoptotic agents that, in turn, increased the proliferative potential of cardiomyocytes and enhanced survival of host myocardium. This is the first report of endogenous cardiomy...

Heart repair gets new muscle

...s not so clear-cut. It has long been thought that cardiac cells (cardiomyocytes) lack the capacity for self-...grate to the damaged tissue and differentiate into cardiac muscle cells. Epstein and colleagues argue that Spoc cells are more likely to be precursors to card...

Buying Time Through Hibernation on Demand

...e blood-loss injury, hypothermia, malignant fever, cardiac arrest and stroke. The potential medical benefits also include improving cancer treatment by allowing patients to tolerate higher radiation doses without damaging healthy tissue. Cancer cells, Roth explained, aren't dependent on oxygen to grow. As a...

U-M team recovers ancient whale in Egyptian desert

...e blood-loss injury, hypothermia, malignant fever, cardiac arrest and stroke. The potential medical benefits also include improving cancer treatment by allowing patients to tolerate higher radiation doses without damaging healthy tissue. Cancer cells, Roth explained, aren't dependent on oxygen to grow. As a...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

...ortic aneurysm and carefully search for associated cardiac symptoms," said author Pierre Amarenco, M.D., of Bichat University Hospital in Paris. Beyond the immediate clinical implications, the study may offer more important clues for further research. It may be that dolichoectasia causes or contributes to s...

Duke engineers develop new 3-D cardiac imaging probe

...ng have created a new three-dimensional ultrasound cardiac imaging probe. Inserted inside the esophagus, the ...tional Science Foundation. One form of ultrasound cardiac imaging, called transesophageal echocardiography (TEE), is conducted on hundreds of people each day ...

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