Leptin found to control appetite and limb development in frogs
... prey. For these tadpoles, the leptin signal isn't capable of turning the feeding behavior off, but it does apparently tell their bodies that they've had enough to eat now, and they can begin sprouting limbs. "Leptin gets a lot of attention for its role in food intake, but it's clear that it does lots of o...Scientists take 'snapshots' of enzyme action
...fers a hydride ion to it. That makes the FAD group capable of accepting molecular oxygen. Then, when the substrate arrives, the cofactor leaves so that the substrate can bind to the same site on the FAD group. At this moment an oxygen atom from molecular oxygen is attached to the substrate, and the hydride i...NYU researchers decorate virus particles, showing potential to enhance MRI capabilities
...onger to tumble in solution, it should become more capable of influencing the response of neighboring water molecules. Our study provides evidence that this effect works. Since the signal that radiologists observe in MRI scans is generated primarily from water molecules within the body, we potentially have t...Smell of success for nanobiosensors
...nto contact with different odorants, the system is capable of detecting odorants at concentrations that would...ense, new high accuracy electronic instrumentation capable of performing electrical measurements at the nanoscale level has been developed and adapted to an at...UCSD researchers develop 'smart petri dish'
.... This enabled them to produce a photonic crystal, capable of controlling light within the structure analogous to the way that semiconductors transmit electricity through computer chips. By attaching rat liver cells to the polystyrene within the crystals and measuring the scattering of light with a sensitive...Tumor wizardry wards off attacks from the immune system
...al wizard Harry Potter, some cancerous tumors seem capable of wrapping themselves in an invisibility cloak. Researchers at Washington University School of Medicine in St. Louis have found that pancreatic tumors hide from the body's immune surveillance by surrounding themselves with cells that make it hard fo...Ready, set, mutate?and may the best microbe win
...ations gave rise to just six populations that were capable of vying for dominance," said lead researcher Yous...ved to have occurred, only about 700 of those were capable of creating a new variant of the target gene. In all, the researchers identified 343 unique strains,...Life and death in the hippocampus: what young neurons need to survive
...jected a virus carrying a pair of molecular shears capable of deleting a gene encoding part of the NMDA receptor into the hippocampus, a brain region harboring neural stem cells that give rise to new neurons. Newly born neurons infected with virus were marked by a fluorescent dye enabling detection of neuron......is in the process of finding an industrial partner capable of commercializing these inventions. Quantum dots, one of the smallest nanoscience research tools, range from 2 to 10 nanometers in diameter; nearly 3 million quantum dots would be needed to fit within the width of a thumb. By virtue of their disti...Possible birthplace of malignant brain tumors identified
...of cells with demonstrated stem cell properties is capable of initiating tumor formation," wrote the researchers. Using tracers, the researchers discovered that PDGFRá is, indeed, found on the stem cells in both mouse and human brain tissue. They also found that the receptor is triggered by PDGF in the ste...A new tool against brain disease
...sprogrammed," he said. "And we found that they are capable of functioning; they've just been turned off." Similarly, the researchers also found that blocking PD-1 restored helper T cell function. "This was the most striking finding, because the majority of patients we have studied had no detectable lev...How HIV 'exhausts' killer T cells
...sprogrammed," he said. "And we found that they are capable of functioning; they've just been turned off." Similarly, the researchers also found that blocking PD-1 restored helper T cell function. "This was the most striking finding, because the majority of patients we have studied had no detectable lev...Neurons grown from embryonic stem cells restore function in paralyzed rats
...mbination of transplanted motor neurons, chemicals capable of overcoming signals that inhibit axon growth, and a nerve growth factor to attract axons to muscles. The report is published in the July 2006 issue of Annals of Neurology.* "This work is a remarkable advance that can help us understand how stem c...Wild bees and the flowers they pollinate are disappearing together
...ther surviving insect pollinators are similar, and capable of pollinating the same flower species. However, this is not the case. The research found for both bees and hoverflies, the "winners" and "losers" were consistently different; insects which pollinate a limited range of flower species or which have sp...DOE JGI finishes 100th microbial genome
...in even the world's most extreme environments, are capable of performing myriad biological functions, learned over the billions of years they have inhabited the planet. Those lessons, and how they can be captured to render clean renewable sources of energy and to repair damaged environments, are among the m...DOE JGI sequences, releases genome of symbiotic tree fungus
...mass that can be converted to fuels, and for trees capable of capturing more carbon from the atmosphere," said DOE JGI Director Eddy Rubin. "The woody tissues of trees act as one of the world's most important terrestrial sinks for CO2, making trees an important stabilizer of carbon in the earth's environme...Microbes hitchhike across Atlantic on desert dust
...osphere each year. The largest of these events is capable of dispersing large quantities of dust across ocea...analysis identified a number of bacteria and fungi capable of causing disease in animals and plants, including the cause of Florida Sycamore canker. "It is te...Radiation-killed bacteria vaccine induces broad immune response in mice
...rom live, weakened Listeria bacteria were believed capable of eliciting a T-cell response. "This advance is potentially of great importance in meeting the challenge of creating vaccines that are safe, effective and simple to manufacture and transport," says NIH Director Elias A. Zerhouni, M.D. Ideall...Researchers add crucial information on how the body's T cells react to parasitic diseases
...n a few peptides, despite having some 12,000 genes capable of generating hundreds of thousands of potential targets for T cells." The study was just published in the online journal PLOS Pathogens, a peer-reviewed, open-access journal published by the Public Library of Science. Other authors of the paper in...Survival of the selfless - scientists find cheats don't always prosper
...r MacLean adds: "While microbes are obviously not capable of rational thought, they can change their behaviour rapidly in response to simple environmental cues. The possibility that one type could become both a cheater and a cooperator depending on what's needed at the time is intriguing. We hope examining ...