Researchers from the University of Navarra analyze new kinds of cancer-fighting antibodies
...egies currently being used to treat cancer, and is capable of interacting with the current treatments so as to make both forms of treatment more powerful. Currently this treatment is being tested in patients with melanoma, kidney and ovarian cancer because there are more ways of measuring the response of...Changes in amino acids in the 1918 influenza virus cut transmission
...hich was caused by a novel influenza subtype virus capable of causing severe respiratory disease and death," says Dr. García-Sastre. "So if we can understand the molecular mechanisms behind its transmission, perhaps we can do something to block transmission and prevent illness." To do this, Dr. García-Sas...Metacognition: Faced with a test, rats can check their knowledge first
Researchers have found evidence that rats are capable of metacognition—that is, they can possess knowledge of their own cognitive states. This ability, which can also be thought of as the capacity to assess or reflect on one's own mental processes, was previously only recognized in humans and other prim...Bypassing eggs, flu vaccine grown in insect cells shows promise
...u vaccine that relies on a different technology is capable of being produced in large amounts much more quickly, a key advantage if a bird flu pandemic were to occur. “Eggs can be very cumbersome to work with,?said John Treanor, M.D., the flu expert at the University of Rochester Medical Center who led th...Loss of a universal tRNA feature reported
...he presence of an RNase P enzyme that is no longer capable of catalyzing abnormal cleavage at the -1 position in the tRNAHis precursor. It will also be revealing to see how different aminoacyl-tRNA synthetases have adapted to discriminate between their cognate or related substrates and the now less distincti...Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex
...en working to develop mass spectrometry techniques capable of sequencing minute amounts of protein from human tumors. "I realized when I read the New York Times article and saw Mary Schweitzer’s story of having uncovered this dinosaur that this is exactly the sort of thing that would appeal to John and he...Liver regeneration may be simpler than previously thought
...processes may explain why the liver is so uniquely capable of renewal and repair after injury, the scientists thought. Karp's team considered two samples of mice. The first consisted of embryonic mice at various stages of development while the second was composed of adult mice to which two-thirds of their...Progress toward artificial photosynthesis?
...only a few special metal catalysts are known to be capable of breaking the C–O bonds in CO2. In contrast to most previous approaches, Antonietti’s team worked with metal-free catalysts, turning toward plants for inspiration. Photosynthesis in modern green plants involves an important intermediate step: th...Scientists discover new, readily available source of stem cells
...o began the work seven years ago. "These cells are capable of extensive self-renewal, a defining property of ...ble human embryonic stem cells, which are believed capable of generating every type of adult cell. "The full range of cells that AFS cells can give rise to ...New mechanism for nutrient uptake discovered
...surface of the cell's outer membrane. Each pore is capable of transporting nutrients individually, so we were really surprised to find that the pores simply can't act without stimulation from their neighbors." In earlier research the Carnegie scientists, with colleagues, identified the genes responsible f...ATR checkpoint-activating DNA structure
...The elucidation of the first defined DNA structure capable of eliciting the ATR checkpoint will aid researchers to further identify additional checkpoint proteins, as well as understand how checkpoint signals are generated and regulated inside the cell....Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine
... contain receptors on their cell surfaces that are capable of recognizing and binding to tumor-related antige...g approach may allow scientists to design vaccines capable of directly stimulating helper T cells, aiding the development of vaccines not only for cancer but a...Wheat can fatally starve insect predators
...3, one of a group of substances called lectins, is capable of binding with a carbohydrate complex in the Hess...Hessian fly larvae, which are called virulent, are capable of ridding their bodies of lectin and surviving. Avirulent larvae are unable to deactivate the lecti...New cell type identified in cancer development
...self-sustaining, self-renewing and multipotent, or capable of creating other types of cells and tissues. These cells are different from normal stem cells, however, in that injecting even as few as 100 of them into laboratory animals will cause cancer. Scientists have dubbed these cancer stem cells. Cancer...Scientists find potential 'off-switch' for HIV virus
...er enzyme within the affected cell called SirT1 is capable of pulling the chemical tail off the Tat protein, rendering it silent. The interplay between p300 and SirT1 comprises the resistor and can effectively keep the virus in its dormant phase. "SirT1 reduces the strength of the signal to replicate," W...Scripps research study reveals structural dynamics of single prion molecules
...Deniz noted: "No single native unfolded protein is capable of initiating the amyloid cascade because of this constant shape-shifting. To start the amyloid conversion process, it has to first convert to an intermediate species, consisting of multiple protein molecules. This insight may be important to finding...Researchers develop technique for bacteria crowd control
...r bacteria with different motility. The device, capable to change the thickness of a film from 1mm to 1 micron (with accuracy of 5 percent) and control the position of electrodes, is intended to separate and concentrate small quantities of live /dead microorganisms in confined spaces. It can be used for t...New study may show how to forestall a fatal, virus-caused immune-system meltdown
...wly developed protein-scanning chip and a uniquely capable computer database to examine the activation and deactivation of more than a thousand proteins in cells from guinea pigs infected with two different strains of Pichinde virus. Guinea pigs infected with one of the Pichinde strains experience no ill eff...Scientists unveil piece of HIV protein that may be key to AIDS vaccine development
...ng could help in the development of an HIV vaccine capable of eliciting a robust antibody response." For years, AIDS vaccine developers have been stymied by the seemingly unlimited ways HIV eludes natural and vaccine-induced immune defenses. Notes Dr. Kwong, "The more we learned about HIV, the more we re...RNA enzyme structure offers a glimpse into the origins of life
... Robertson said. "With that, you would have an RNA capable of making copies of itself; mutations or errors in some copies would result in variations that would be acted on by Darwinian natural selection, and the molecules would evolve into bigger and better ribozymes. That's what makes this structure so inte...